Laboratory Head in Neuropathology

vor 3 Wochen


Basel, Basel-Stadt, Schweiz Roche Vollzeit

About the Role

We are seeking an exceptional Laboratory Head in Neuropathology to join our team at Roche. As a key member of our Pharmaceutical Research and Early Development organization, you will play a critical role in advancing our understanding of neurodegenerative diseases and developing innovative therapeutics.

Key Responsibilities

  • Lead a team of scientists to understand and quantify neurodegenerative disease pathology in animal models and human post-mortem tissues and biofluids.
  • Bring deep scientific expertise to multiple projects, focusing on the pathology-relevant microenvironment and its impact on neurodegenerative diseases.
  • Generate ideas for back translation from clinical trial samples and data to target and/or biomarker identification.
  • Interface with omics and in vivo and in vitro models colleagues to design and interpret experiments.
  • Lead drug discovery projects related to neurodegenerative disorders.

Requirements

  • PhD or MD/PhD in neuroscience or cellular biology with a minimum of 5 years of experience in Neuropathology.
  • Deep understanding and practical experience in cellular neuroscience, including major neural cell type histology in preclinical disease rodent/larger mammal models and post-mortem patient samples.
  • Expertise in neurodegenerative diseases such as Alzheimer's, Parkinson's, ALS, and/or Multiple Sclerosis, including a solid grasp of the literature in neurodegeneration.
  • Experience using multi-omics approaches such as proteomics, transcriptomics, and/or single cell genomics to quantify differences in disease state, with experience integrating two or more of these omics approaches a plus.
  • Proven scientific-track record through impactful publications in relevant fields, patents, or substantial contributions to drug development programs.
  • Driven by the desire to find therapeutics for some of the most complicated and devastating disorders.
  • Enjoy teamwork, diligence, and efficiency, with a kind and influential team leadership style.

About Roche

Roche is committed to recognizing talent and aptitude, and we prioritize encouraging and supporting our employees on their personal journeys. We believe that diverse perspectives and experiences are essential to finding innovative solutions and challenging the status quo. We are dedicated to building a team that represents a range of backgrounds, perspectives, and skills, and we are confident that this diversity will drive our success.



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