Lab Head and Research Project Leader in Amyloid Biochemistry and Neurodegeneration

vor 4 Wochen


Basel, Basel-Stadt, Schweiz Roche Vollzeit

About the Role

We are seeking a highly skilled and experienced Research Project Leader to join our team at Roche's Pharmaceutical Research and Early Development organization (pRED). As a key member of our Neural Signaling research section, you will be responsible for leading a lab focused on exploring and understanding neurodegenerative disease processes in vitro biochemically and in cells, in animal models, next generation human model systems and human post-mortem tissues and biofluids.

Key Responsibilities

  • Lead a cross-functional project team of scientists from within NRD and other specialized departments to deliver on portfolio and contribute to the overall research strategy of NRD.
  • Operate at the exciting interface of neuropathology, biochemistry, biophysics, structural biology, and cutting-edge multi-omics.
  • Develop and implement innovative research strategies to advance our understanding of neurodegenerative diseases.
  • Collaborate with world-class scientists and drug hunters to identify and develop novel therapeutic approaches.

Requirements

  • PhD or MD/PhD in neuroscience, biochemistry, structural biology, biophysics, molecular or cellular biology with a strong motivation and passion for translating preclinical research to clinical applications.
  • At least 5 years of experience leading laboratory or drug discovery projects in Biotech / Pharma R&D or in a similar environment in academia.
  • Proven scientific-track record through impactful publications in relevant fields exemplifying expertise in biochemical and cellular mechanisms related to protein metabolism and in-depth hands-on disease expertise in Alzheimer's disease.

About Roche

Roche is committed to recognizing talent and aptitude, and we prioritize encouraging and supporting our employees on their personal journeys. We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way, and we are devoted to building a team that represents a range of backgrounds, perspectives, and skills.



  • Basel, Basel-Stadt, Schweiz Roche Vollzeit

    About the RoleThis is a unique opportunity to lead a research lab in Roche's Pharmaceutical Research and Early Development organization (pRED), focusing on neurodegenerative diseases such as Alzheimer's and Parkinson's.As a Senior Research Project Leader, you will be responsible for building and leading a team of scientists to explore and understand...


  • Basel, Basel-Stadt, Schweiz Roche Vollzeit

    The PositionWe are seeking an exceptional Scientific Leader in Neurodegenerative Diseases to join our research team at Roche. In this role, you will lead a laboratory focused on understanding the biochemical mechanisms of neurodegenerative diseases.As a Research Leader, you will be responsible for developing and executing research projects aimed at...


  • Basel, Basel-Stadt, Schweiz Roche Vollzeit

    Transformative Medicine for PatientsIn Roche's Pharmaceutical Research and Early Development organization (pRED), we tackle some of the world's toughest unmet healthcare needs. Our mission is to transform science into medicines, creating a culture of curiosity, responsibility, and humility where talented people are empowered to bring forward life-changing...


  • Basel, Basel-Stadt, Schweiz skills matter sp. z o. o. Vollzeit

    Senior Project Manager Job OpportunityAt skills matter, we're on the hunt for a seasoned Senior Project Manager to spearhead our large-scale digitalisation project within the Science and Research domain. This is an exceptional chance to drive innovation and lead a team of approximately 10 professionals in delivering cutting-edge solutions.Key...


  • Basel, Basel-Stadt, Schweiz Roche Vollzeit

    The OpportunityRoche's Pharmaceutical Research and Early Development organization (pRED) is seeking a highly skilled Research Leader to join our Neuroscience and Rare Disease (NRD) therapeutic area. As a Laboratory Head, you will lead a Neuromuscular Research Group focused on developing innovative therapeutics for neuromuscular disorders.Key...


  • Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel Vollzeit

    Your PositionThe Biozentrum, University of Basel, seeks a highly motivated researcher to join our team in the development of innovative cartilage and osteochondral bioprinting technologies for joint restoration. As a PhD candidate, you will work closely with our experienced team to advance the field of tissue engineering and regenerative medicine. Your...

  • Proteomics Researcher

    vor 3 Wochen


    Basel, Basel-Stadt, Schweiz Friedrich Miescher Institute for Biomedical Research Vollzeit

    About the PositionWe are seeking a skilled and proactive Proteomics Specialist to collaborate on proteomics projects from conception to publication.In this role, you will apply and develop state-of-the-art proteomics technologies, operate and maintain advanced LC-MS instrumentation, analyze proteomics mass spectrometry data using the latest software, and...


  • Basel, Basel-Stadt, Schweiz Roche Vollzeit

    The PositionWe are seeking a highly skilled Laboratory Head to lead a Neuromuscular Research Group in the Neurotechnologies section within the Neuroscience and Rare Disease (NRD) therapeutic area at Roche.The primary focus of the section is on implementing and using novel delivery and RNA/DNA modifying techniques, as well as establishing suitable muscle...


  • Basel, Basel-Stadt, Schweiz Roche Vollzeit

    About the RoleWe are seeking a highly skilled and experienced Research Scientist to lead our Neuromuscular Research Group at Roche. As a key member of our team, you will be responsible for developing and implementing research strategies to advance our understanding of neuromuscular diseases.Key ResponsibilitiesLead a team of scientists to design and execute...

  • Proteomics Researcher

    vor 2 Wochen


    Basel, Basel-Stadt, Schweiz Friedrich Miescher Institute for Biomedical Research Vollzeit

        Role OverviewWe are seeking an experienced Proteomics Specialist to join our dynamic team at the Friedrich Miescher Institute for Biomedical Research. The ideal candidate will be passionate about applying cutting-edge proteomics technologies in multi-disciplinary research projects.Key ResponsibilitiesCollaborate on proteomics projects from conception...


  • Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel Vollzeit

    Your PositionThe Biozentrum, University of Basel, is seeking a highly motivated researcher to join our team in the field of cartilage and osteochondral bioprinting for joint restoration. The project aims to develop novel bioprinting techniques using nasal chondrocytes and Melt Electrowriting (MEW) to create functional cartilage and osteochondral grafts for...


  • Basel, Basel-Stadt, Schweiz Universität Basel Vollzeit

    About the PositionWe are seeking a highly motivated and experienced researcher to join our research group at the Universität Basel. The position is available for a PhD in Biopharmacy, focusing on understanding the processes governing drug absorption, distribution, metabolism, and elimination (ADME).Key ResponsibilitiesDesign and conduct molecular biological...


  • Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel Vollzeit

    Your RoleAs a Research and Teaching Assistant at The Biozentrum, University of Basel, you will play a crucial role in supporting our research projects in the FX market and the interbank money market. Your responsibilities will include assisting with data analysis, preparing teaching materials, and contributing to the development of academic content.Your...

  • Scientific Team Lead

    vor 4 Wochen


    Basel, Basel-Stadt, Schweiz Novartis Vollzeit

    Job Title: Scientific Team LeadJob Summary:We are seeking a highly motivated and experienced Scientific Team Lead to join our team at Novartis. As a key member of our Oncology Research team, you will be responsible for managing and coordinating complex activities in our RLT and oncology in vivo labs.Responsibilities:* Manage and coordinate the activities of...

  • Research Scientist

    vor 2 Wochen


    Basel, Basel-Stadt, Schweiz Universitätspital Basel Vollzeit

    Job DescriptionSupport Research ProjectsAs a research scientist at the Universitätspital Basel, you will support several research projects in the implementation and development of parametric causal inference methods. This involves working closely with our team to design and implement study protocols, manage cohort data, and perform statistical analyses...

  • Senior Project Manager

    vor 4 Wochen


    Basel, Basel-Stadt, Schweiz skills matter sp. z o. o. Vollzeit

    Senior Project ManagerWe are seeking a highly skilled Senior Project Manager to lead our digitisation project in the Science and Research business domain. The successful candidate will be responsible for scaling existing solutions for the new centre, leading a team of approximately 10 people, and managing project scope, budget, and timelines effectively.Key...


  • Basel, Basel-Stadt, Schweiz unisite ag Vollzeit

    About the RoleWe are seeking a highly skilled Global IT Consultant for Research and Development to join our team at unisite ag. As a key member of our IT RDM Biological Sample Production and Management team, you will be responsible for developing, supporting, and managing IT solutions for biological research and development globally.Your primary focus will...


  • Basel, Basel-Stadt, Schweiz Roche Vollzeit

    About the RoleWe are seeking a highly skilled and experienced Neuropathology expert to lead our research team in the Neuroscience and Rare Disease therapeutic area. As a key member of our team, you will be responsible for understanding and quantifying neurodegenerative disease pathology in animal models and human post-mortem tissues and biofluids.Key...


  • Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel Vollzeit

    Your RoleThe Biozentrum, University of Basel, is seeking a highly motivated PhD candidate to join our team in the field of cartilage and osteochondral bioprinting for joint restoration. The successful candidate will be part of a dynamic and interdisciplinary research environment, working closely with our team to develop innovative solutions for cartilage and...


  • Basel, Basel-Stadt, Schweiz skills matter sp. z o. o. Vollzeit

    {"header":{"title":"Senior Project Manager Position","subTitle":"Lead a Digitization Project in Science and Research"},"content":"We are looking for a Senior Project Manager to lead a digitization project in the Science and Research business domain. The project aims to scale existing solutions for the new centre.You will work together with another project...