Laboratory Head in Neuropathology
vor 3 Wochen
The Position
In Roche’s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.
This position is located in Neurogenomics, a research section within the Neuroscience and Rare Disease (NRD) therapeutic area, where the primary focus is using genetics and genomics to suggest therapeutic targets, develop a better understanding of disease biology, identify potential biomarkers, and develop therapeutics for some of the most challenging neurological disorders. Our section works closely with other sections and groups within NRD as well as laboratories within our Therapeutic Modalities and Pharmaceutical Sciences groups and Data & Analytics to convert hypotheses into innovative therapeutics for brain disorders across the lifespan.
Job mission
We are offering an outstanding opportunity to recruit and lead a lab whose primary focus will be to understand and quantify neurodegenerative disease pathology in animal models and human post-mortem tissues and biofluids.
With a deep knowledge and experience in Neuropathology, you will operate at the exciting interface of histopathology and cutting-edge multi-omics. You will have tremendous resources and capabilities, and you will be surrounded by world-class scientists and drug hunters in a state-of-the-art new building located at the pRED center in Basel.
Your key responsibilities
You are recruiting and leading an effective team to understand pathology of neurodegenerative diseases at the cellular level by performing quantitative histopathology, spatial omics, and related experiments.
You are bringing deep scientific expertise about the pathology-relevant microenvironment how different cell types influence each other) during the neurodegenerative process as a key contributor to multiple projects.
You are generating ideas for back translation from clinical trial samples and data to target and/or biomarker identification
You are interfacing with omics and in vivo and in vitro models colleagues to design and interpret experiments
You are leading drug discovery projects related to neurodegenerative disorders.
Who you are:
PhD or MD/PhD in neuroscience or cellular biology with minimum 5 years of experience in Neuropathology
You are a rigorous scientist with a deep understanding and practical experience in cellular neuroscience, including major neural cell type histology in preclinical disease rodent/larger mammal models and post-mortem patient samples
You have expertise in neurodegenerative diseases such as Alzheimer’s, Parkinson’s, ALS, and/or Multiple Sclerosis, including a solid grasp of the literature in neurodegeneration
You have experience using multi-omics approaches such as proteomics, transcriptomics, and/or single cell genomics to quantify differences in disease state, with experience integrating two or more of these omics approaches a plus
You bring a proven scientific-track record through impactful publications in relevant fields, patents, or substantial contributions to drug development programs
You are someone who is driven by the desire to find therapeutics for some of the most complicated and devastating disorders
You enjoy teamwork, diligence and efficiency. You are a kind and influential team leader and a trusted and knowledgeable colleague
Working in a multicultural environment motivates you
Our commitment
Roche commits to recognising talent and aptitude. We prioritize encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions and grow in their career.
We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.
-
Laboratory Head in Neuromuscular Disease
vor 1 Monat
Basel, Schweiz Roche VollzeitThe Position In Roche’sPharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility...
-
Laboratory Head in Neuromuscular Disease
vor 3 Wochen
Basel, Schweiz Roche VollzeitThe Position In Roche’sPharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility...
-
Basel, Schweiz Roche VollzeitThe Position The Position In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by...
-
Basel, Schweiz Roche VollzeitThe Position The Position In Roche’s Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by...
-
Basel, Basel-Stadt, Schweiz Roche VollzeitThe Position The Position In Roche's Pharmaceutical Research and Early Development organization (pRED), we make transformative medicines for patients in order to tackle some of the world's toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity,...
-
Veterinarian for Animal Facilities 1
Vor 7 Tagen
Basel, Schweiz Universität Basel VollzeitThe University of Basel has an international reputation of outstanding achievements in research and teaching. Founded in 1460, it is the oldest university in Switzerland and has a history of success going back more than 550 years. In Life Sciences animal experiments still are an essential part of success - even though there has been great progress in the...
-
Veterinarian for Animal Facilities 1
Vor 7 Tagen
Basel, Basel-Stadt, Schweiz Universität Basel VollzeitThe University of Basel has an international reputation of outstanding achievements in research and teaching. Founded in 1460, it is the oldest university in Switzerland and has a history of success going back more than 550 years.In Life Sciences animal experiments still are an essential part of success - even though there has been great progress in the...
-
QC Sector Head Bioassays
vor 1 Monat
Basel, Schweiz Lonza VollzeitLocated in our successful CDMO Business Unit currently offers exciting opportunities. Become part of a group that enables its customers to meet some of the greatest challenges in patient treatment and join us by applying for the position as QC Sector Head Bioassays for a new sterile Drug product facility to support quality control and manufacturing...
-
QC Sector Head Bioassays
vor 3 Wochen
Basel, Schweiz Lonza VollzeitLocated in our successful CDMO Business Unit currently offers exciting opportunities. Become part of a group that enables its customers to meet some of the greatest challenges in patient treatment and join us by applying for the position as QC Sector Head Bioassays for a new sterile Drug product facility to support quality control and manufacturing...
-
Facility Management Team Leader 80-100%
vor 4 Wochen
Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel VollzeitIOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its related diseases and to develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded. **Responsibilities**: - Being in charge of building...
-
Facility Management Team Leader 80-100%
vor 21 Stunden
Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel VollzeitIOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its related diseases and to develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded. **Responsibilities**: - Being in charge of building...
-
Head of Quality Control Operations
vor 2 Monaten
Basel, Schweiz Takeda Pharmaceutical Vollzeit**Job Title**:Head of Quality Control Operations **Location**: Neuchâtel **About** the **role**: Directs the Quality Control Laboratories (Microbiology, Biochemistry, Lab Support and Quality Sterility Assurance) in a large size plant and directs a large department to support Facility, Division and Corporate wide initiatives. Responsible for performances...
-
Scientific Associate
vor 2 Monaten
Basel, Schweiz Coopers Group AG VollzeitScientific Associate - Oncology For our international client in the pharmceutical industry in Basel we are looking for a hands-on professional. (temporary until end of 2023) **Tasks & Responsibilities** - Independently perform in vitro experiments under the leadership of the assigned lab head(s); interpret and report data of the respective experiments -...
-
Scientific Associate
vor 3 Wochen
Basel, Schweiz Coopers Group AG VollzeitScientific Associate - Oncology For our international client in the pharmceutical industry in Basel we are looking for a hands-on professional. (temporary until end of 2023) **Tasks & Responsibilities** - Independently perform in vitro experiments under the leadership of the assigned lab head(s); interpret and report data of the respective experiments -...
-
Head of Quality Control Operations
Vor 7 Tagen
Basel, Basel-Stadt, Schweiz Takeda Pharmaceutical VollzeitJob Title:Head of Quality Control OperationsLocation: NeuchâtelAbout the role:Directs the Quality Control Laboratories (Microbiology, Biochemistry, Lab Support and Quality Sterility Assurance) in a large size plant and directs a large department to support Facility, Division and Corporate wide initiatives.Responsible for performances of lab processes,...
-
Scientific Associate
Vor 7 Tagen
Basel, Basel-Stadt, Schweiz Coopers Group AG VollzeitScientific Associate - OncologyFor our international client in the pharmceutical industry in Basel we are looking for a hands-on professional.(temporary until end of 2023)Tasks & Responsibilities Independently perform in vitro experiments under the leadership of the assigned lab head(s); interpret and report data of the respective experiments Closely work...
-
Scientific Associate
vor 2 Monaten
Basel, Schweiz CTC Resourcing Solutions Vollzeit**The Life Science Career Network** Our client is a leading global player in the Pharmaceutical industry with global headquarters in Basel, Switzerland. The organisation focusses on novel therapies in Oncology and Ophthalmology and is also currently developing a world-leading pipeline in Neuroscience and Dermatology with one of the strongest pipelines of...
-
Administrative Assistant
vor 2 Wochen
Basel, Schweiz CTC Resourcing Solutions Vollzeit**_The Life Science Career Network_** **Administrative Assistant** Our client is a pioneer in Drug Discovery and Development and one of the frontrunners in Personalised Healthcare. As the world's largest R&D spender in the pharmaceutical and diagnostics domain, they work in a vast number of drug discovery & therapeutic areas and are highly recognized...
-
Head of Quality Compliance and Systems
vor 1 Woche
Basel, Schweiz Takeda Pharmaceutical Vollzeit**About the role**: **A unique opportunity is now available for the Head of Quality Compliance & Systems position located at our biological production site in Neuchâtel.**: **You will have the overall responsibility to oversee that the processes are effectively established and maintained. Additionally, you'll play a pivotal role in enhancing the overall...
-
Lab Manager Assistant
vor 3 Wochen
Basel, Schweiz ITech Consult VollzeitFor our customer a big pharmaceutical company in Basel we are looking for a highly qualified Lab Manager Assistant Tasks & Responsibilities**:Device Management: together with researchers, the Lab Manager assistant supports in the proper acquisition, maintenance, repair and disposal of equipment.** - Assisting in the ordering of material in collaboration...
