Senior Research Project Leader in Amyloid Biochemistry and Neurodegeneration

vor 1 Monat

Basel, Basel-Stadt, Schweiz Roche Vollzeit

About the Role

This is a unique opportunity to lead a research lab in Roche's Pharmaceutical Research and Early Development organization (pRED), focusing on neurodegenerative diseases such as Alzheimer's and Parkinson's.

As a Senior Research Project Leader, you will be responsible for building and leading a team of scientists to explore and understand neurodegenerative disease processes in vitro biochemically and in cells, in animal models, next generation human model systems, and human post-mortem tissues and biofluids.

With your expertise in amyloid biochemistry and Alzheimer's disease pathomechanism, you will operate at the interface of neuropathology, biochemistry, biophysics, structural biology, and cutting-edge multi-omics.

You will be part of a collaborative and dynamic team, working closely with other research sections within the Neuroscience and Rare Disease (NRD) therapeutic area, and laboratories in our global functions.

About You

  • You have a PhD or MD/PhD in neuroscience, biochemistry, structural biology, biophysics, molecular, or cellular biology with a strong motivation and passion for translating preclinical research to clinical applications.
  • You have at least 5 years of experience leading laboratory or drug discovery projects in Biotech/Pharma R&D or in a similar environment in academia.
  • You are working in a matrix environment, with a proven scientific track record through impactful publications in relevant fields, exemplifying your expertise in biochemical and cellular mechanisms related to protein metabolism, and in-depth hands-on disease expertise in Alzheimer's disease.
  • You bring scientific expertise and technical know-how to utilize and integrate a broad range of techniques, including biochemistry, chromatography, immunoassays, proteomics, spatial-omics, or MALDI approaches to study proteins ex vivo or in situ.
  • You are a rigorous scientist with a deep understanding and practical experience in amyloid biochemistry, as well as a solid grasp of the literature in neurodegeneration.

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