Scientist& Chemical Biology and Screening
vor 2 Wochen
We are looking for a highly motivated Scientist to support one of Ridgeline Discovery’s portfolio companies.
The successful candidate will have experience in biological and biochemical methods, chemical biology approaches as well as compound screening technologies. A proven track record in the field of induced proximity technologies and/or transcriptional networks is an important plus. She/he will be a highly motivated and enthusiastic team player with proven organizational skills and first mentorship and people leadership experience. The candidate has a strong scientific background to impact and lead key areas of our early target discovery pipeline as well as later stage compound characterization and profiling together with exceptional potential and willingness to grow within the company as an initial leader from the bench towards project leader and beyond.
This Basel-based position offers a tremendous opportunity for an early-stage talent and future leader to support one of our latest portfolio companies in an experienced, vibrant, and dynamic biotech team.
RESPONSIBILITIES
- Lead and execute chemical biology approaches to support early-stage drug discovery
- Design, implement, and optimize induced proximity assays for compound screening, profiling, and characterization
- Conduct high-throughput profiling and flowchart assays
- Perform tissue culture and engineer mammalian cell lines to support screening projects
- Transition assays to semi-automation/automation modes to enhance throughput
- Work with diverse chemical libraries, including non-covalent and covalent compounds, molecular glues, and PROTACs
- Analyze data, troubleshoot experiments, and implement innovative solutions
- Collaborate with bioinformaticians to develop and use scripts for data analysis and hit identification
- Document experimental results thoroughly and present findings in internal meetings
QUALIFICATIONS
You are a highly motivated and independent individual with a strong scientific track record in the field of induced proximity. You are an excellent team player and mentor of junior lab personnel with excellent communication and interpersonal skills who is effective at working in a collaborative and diverse environment.
- Educational Background: PhD with relevant postdoctoral experience, or MS / BS with significant industry experience and a proven growth trajectory and project leadership experience in early drug discovery
- Technical Expertise:
- Broad experience in cellular and biochemical technologies
- Proficiency in molecular biology techniques and cell culture across various models
- Hands-on experience with high-capacity, assays and data analysis
- Leadership: Demonstrated ability to lead and mentor in the lab, with a history of scientific contributions and achievements
- Analytical Skills: Skilled in experimental design, data interpretation, and troubleshooting
- Software Proficiency: Experienced with Microsoft Office Suite (Word, PowerPoint, Excel) and GraphPad Prism; basic programming skills are a plus
- Communication: Excellent interpersonal and communication skills in a collaborative environment
- Language: Proficiency in English (spoken and written)
WHAT WE CURRENTLY OFFER
- People: We are an international and diverse team with talented and passionate people.
- Creativity: We offer an innovative and creative environment.
- Development: We support the individual development of our employees.
- Fun: From time-to-time we organise cool off-site summer and winter team events.
- Offices: Our well-equipped laboratories and offices are located at the Tech Park, a premier address for early-stage start-ups in Basel.
- Commuter Benefits: We support our employees tailored to their personal needs in commuting to work and offer parking facilities or a commuter contribution.
- Flexible Working: We support flexible working as appropriate.
- Christmas Closure: In addition to the 24 holidays per year, our offices/labs are closed between Christmas and New Year.
- Birthday Retreat: On top of that, your birthday is your personal holiday - our employees enjoy their birthday with a day off.
- Food: We like get-togethers during lunch time. Enjoy tasty, subsidised meals from our FELFEL food fridge.
- Coffee: Meet up with your colleagues and grab free coffee.
To apply, please submit your completed application form along with your CV, cover letter, and reference letters.
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