Postdoc Position in Quantitative Biology
vor 2 Monaten
The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need. With more than 70 research groups and 800 employees, the Department of Biomedicine is the largest department at the University. We are located in the heart of Basel at 6 different locations. Be part of our future
The mission of the group is to understand fundamental mechanisms regulating short
- and long-term metabolic adaptation to genetic and chemical perturbations to find new and unconventional therapeutic strategies, ranging from antibacterial to anticancer drugs. To this end, we develop new ways to combine state-of-the-art technologies in metabolomics with mathematical modeling.
**Your position**
- Adapting existing and possibly developing improved experimental protocols for the high-throughput metabolomics analysis of drug-perturbed cells.
- Unravel the hidden potential of apparently inactive molecules in interfering with cellular metabolism.
- Support and preparation of scientific reports and journal articles
**Your profile**
Essential:
- PhD in (Bio)Physics, (Bio)engineering, Systems Biology, Bioinformatics/Computational Biology, or related fields.
- Solid experience in data analysis
- Experience with programming language (e.g. Matlab, R or Python) Motivation to work in an international research environment
Highly desirable:
- Experience in kinetic modeling and/or hands-on laboratory experience
- Good communication skills
- Interest in mathematical modeling of metabolic and regulatory/signaling network
**We offer you**
- You will have access to state-of-the-art research equipment in metabolomics and computational biology.
- You will work in a dynamic and highly interdisciplinary team including computer scientists, experimentalists.
- You will be involved in cross-disciplinary collaborations and have training opportunities to further develop and grow your scientific interests.
- Opportunity to work in close contact with other basic
- and clinical-research groups at the Department of Biomedicine and the Biozentrum in Basel
- Support from highly competent, experienced team members and potential to lead projects with a high degree of academic freedom
**Application / Contact**
Key References:
Ortmayr, K., de la Cruz Moreno, R. & Zampieri, M. Expanding the search for small-molecule antibacterials by multidimensional profiling. Nat Chem Biol 18, 584-595 (2022)
Anglada-Girotto, M., Handschin, G., Ortmayr, K. et al. Combining CRISPRi and metabolomics for functional annotation of compound libraries. Nat Chem Biol 18, 482-491 (2022)
Zampieri, M., Hörl, M., Hotz, F. et al. Regulatory mechanisms underlying coordination of amino acid and glucose catabolism in Escherichia coli. Nat Commun 10, 3354 (2019)
Øyås O., Borrell S., Trauner A., et al. Model-based integration of genomics and metabolomics reveals SNP functionality in Mycobacterium tuberculosis. PNAS 117 (2020)
Campos A. and Zampieri M. Metabolomics-Driven Exploration of the Chemical Drug Space to Predict Combination Antimicrobial Therapies. Molecular Cell 74, 1291-1303 (2020)
Apply
-
Postdoc Position: Quantitative Biology of
vor 3 Monaten
Basel, Schweiz Universität Basel Vollzeit**Postdoc position: quantitative biology of non-growing bacteria** **Your position** **Your profile** **We offer you
-
Postdoc Position in Quantitative Biology
vor 2 Monaten
Basel, Schweiz Universität Basel Vollzeit**Postdoc position in quantitative biology (Zampieri Lab)** **Your position** - Adapting existing and possibly developing improved experimental protocols for the high-throughput metabolomics analysis of drug-perturbed cells. - Unravel the hidden potential of apparently inactive molecules in interfering with cellular metabolism. - Support and preparation of...
-
Quantitative Biology Researcher
vor 1 Monat
Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitAbout the PositionThe Biozentrum, University of Basel, is seeking a highly motivated Postdoctoral Researcher to join our team in the field of quantitative biology. As a Postdoc, you will be working closely with our research group to develop and apply model-based and statistical approaches to analyze and interpret large-scale dynamic profiles of small...
-
Postdoc Position: Quantitative Biology of
vor 5 Monaten
Basel, Schweiz Universität Basel VollzeitHow does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world's leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and...
-
Postdoc Position: Quantitative Biology of
vor 5 Monaten
Basel, Schweiz Universität Basel VollzeitHow does life emerge from molecules and cells? This is the central question that motivates us. With curiosity and passion, we investigate the entire spectrum ranging from the atom to the organism. The Biozentrum of the University of Basel is one of the world's leading life sciences institutes. With 32 groups and 500 employees, we are a dynamic and...
-
Postdoc position in quantitative biology
vor 2 Monaten
Basel, Schweiz The Biozentrum, University of Basel VollzeitYour position Apply and develop model-based and statistical approaches to analyze and interpret large scale dynamic profiles of small molecules effects on cancer cell metabolism. Adapting existing and possibly developing improved experimental protocols for the high-throughput metabolomics analysis of drug-perturbed cells. Unravel the hidden...
-
Quantitative Biology Researcher
vor 2 Wochen
Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitYour RoleWe are seeking a highly motivated Postdoctoral Researcher to join our team at The Biozentrum, University of Basel. As a Quantitative Biology Researcher, you will be responsible for developing and applying model-based and statistical approaches to analyze and interpret large-scale dynamic profiles of small molecules effects on cancer cell...
-
Postdoc position in in vitro kidney model development
vor 5 Monaten
Basel, Schweiz Bio Engineering Laboratory & Novartis VollzeitJob description The postdoc will develop new cell-culture platforms and tisssue models intended to mimic the kidney microenvironment. He will use these platforms to culture stem-cell-derived renal cells to realize a renal tubular unit. The postdoc will then focus on the functional characterization of the tubular unit to confirm that the developed...
-
Quantitative Biology Researcher
vor 2 Wochen
Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitYour RoleWe are seeking a highly motivated Postdoctoral Researcher to join our team at The Biozentrum, University of Basel. As a Quantitative Biology Researcher, you will be responsible for developing and applying model-based and statistical approaches to analyze and interpret large-scale dynamic profiles of small molecules effects on cancer cell...
-
Basel, Basel-Stadt, Schweiz Department of Biosystems Science and Engineering VollzeitJob DescriptionWe are seeking a highly motivated and collaborative researcher to join our team at the Department of Biosystems Science and Engineering (D-BSSE) of ETH Zurich in Basel, Switzerland.The ideal candidate will have a PhD degree in Biological Engineering, Molecular Biotechnology, Molecular Medicine, (Quantitative) Biology or a related field and...
-
Quantitative Biology Researcher
vor 1 Monat
Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitAbout the PositionWe are seeking a highly motivated Postdoctoral Researcher to join our team at The Biozentrum, University of Basel. The successful candidate will work on developing and applying model-based and statistical approaches to analyze and interpret large-scale dynamic profiles of small molecules effects on cancer cell metabolism.Key...
-
Quantitative Biology Researcher
vor 2 Monaten
Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitAbout the PositionWe are seeking a highly motivated Postdoctoral Researcher to join our team at The Biozentrum, University of Basel. The successful candidate will work on developing and applying model-based and statistical approaches to analyze and interpret large-scale dynamic profiles of small molecules effects on cancer cell metabolism.Key...
-
Quantitative Biologist Postdoctoral Position
Vor 7 Tagen
Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitYour Role We are seeking a highly motivated Postdoctoral Researcher to join our team at The Biozentrum, University of Basel. As a Postdoctoral Researcher in Quantitative Biology, you will be responsible for developing and applying model-based and statistical approaches to analyze and interpret large-scale dynamic profiles of small molecules effects on...
-
Postdoc in Discovery Sciences
vor 5 Monaten
Basel, Schweiz Novartis Vollzeit393276BR **Postdoc in Discovery Sciences**: Switzerland **About the role** We are seeking an independent and highly motivated researcher to join as a Postdoc Fellow in our dynamic and diverse research team at Novartis. This role presents an exceptional opportunity to engage in the development of translational cellular models and investigate the...
-
Discovery Postdoc
vor 5 Monaten
Basel, Schweiz Novartis Vollzeit392048BR **Discovery Postdoc - Data Science**: Switzerland **About the role** We are seeking to hire a highly motivated discovery postdoc with a background in data science, to lead a research project investigating spatial and single cell expression in liver disease patient samples. You will have the opportunity to work in a matrix team consisting of data...
-
Postdoc Fellowship in Population/conservation
vor 5 Monaten
Basel, Schweiz Universität Basel Vollzeit**Your position** Our new research projects generally focus on (a) genomic signatures of climate adaptation, (b) signatures of genetic drift, including mutational load, and (c) conservation genomics. Our group has recently (long-read-) sequenced the genomes of individuals of many populations of North American Arabidopsis, and of a handful of Brassicaceae...
-
Postdoc Position in Ai-based Drug Discovery
vor 5 Monaten
Basel, Schweiz Universität Basel Vollzeit**Your assignments** The PostDoc position is available to extend ongoing research on the development of novel algorithms for drug design combining physics-based modeling with deep neural network concepts. You will be responsible for the development and implementation of novel deep neural network models based on recent developments in diffusion models and...
-
Two Phd
vor 5 Monaten
Basel, Schweiz Universität Basel Vollzeit**Your position** - You will have the opportunity to carry out academic research in an English-speaking environment. The focus of our group is on central banking, financial market and bank regulation, and the economics of banking. Teaching duties may be carried out in German or English. - PhD position: The position will entail a performance review after one...
-
Basel, Schweiz Bio Engineering Laboratory & Novartis VollzeitJob description In this project, we aim at exploring how in vitro models can be leveraged to improve preclinical drug selection, in particular for gene therapy development. Building on the group expertise in blood-brain-barrier platforms, the postdoc will develop new in vitro models of the human and mouse blood-brain-barrier and benchmark the in vitro...
-
Phd Student Position
vor 3 Monaten
Basel, Schweiz Universität Basel VollzeitThe Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need. With more than 70 research groups and 800 employees, the...