Scientist, Chemical Biology and Screening

vor 2 Monaten


Basel, Schweiz Ridgeline Discovery GmbH Vollzeit

Ridgeline Discovery, a Versant Ventures Discovery Engine, creates and operates Versant-financed innovative biotech companies in partnership with entrepreneurs, industry, and leading academics. In recent years, Ridgeline has assembled an international team of >50 highly experienced drug discovery and industry professionals and built and operated multiple new successful companies; these companies have raised significant funds through Series A, B, IPO and an exit through a trade sale.

We are looking for a highly motivated **Scientist **to support one of Ridgeline Discovery’s portfolio companies.

This Basel-based position offers a tremendous opportunity for an early-stage talent and future leader to support one of our latest portfolio companies in an experienced, vibrant, and dynamic biotech team.

**RESPONSIBILITIES**
- Lead and execute chemical biology approaches to support early-stage drug discovery
- Design, implement, and optimize induced proximity assays for compound screening, profiling, and characterization
- Conduct high-throughput profiling and flowchart assays
- Perform tissue culture and engineer mammalian cell lines to support screening projects
- Transition assays to semi-automation/automation modes to enhance throughput
- Work with diverse chemical libraries, including non-covalent and covalent compounds, molecular glues, and PROTACs
- Analyze data, troubleshoot experiments, and implement innovative solutions
- Collaborate with bioinformaticians to develop and use scripts for data analysis and hit identification
- Document experimental results thoroughly and present findings in internal meetings

**QUALIFICATIONS**

You are a highly motivated and independent individual with a strong scientific track record in the field of induced proximity. You are an excellent team player and mentor of junior lab personnel with excellent communication and interpersonal skills who is effective at working in a collaborative and diverse environment.
- ** Educational Background**: PhD with relevant postdoctoral experience, or MS / BS with significant industry experience and a proven growth trajectory and project leadership experience in early drug discovery
- ** Technical Expertise**:

- Broad experience in cellular and biochemical technologies
- Proficiency in molecular biology techniques and cell culture across various models
- Hands-on experience with high-capacity, assays and data analysis
- ** Leadership**: Demonstrated ability to lead and mentor in the lab, with a history of scientific contributions and achievements
- ** Analytical Skills**: Skilled in experimental design, data interpretation, and troubleshooting
- ** Software Proficiency**: Experienced with Microsoft Office Suite (Word, PowerPoint, Excel) and GraphPad Prism; basic programming skills are a plus
- ** Communication**:Excellent interpersonal and communication skills in a collaborative environment
- ** Language**:Proficiency in English (spoken and written)

**WHAT WE CURRENTLY OFFER**
- ** People**: We are an international and diverse team with talented and passionate people.
- ** Creativity**: We offer an innovative and creative environment.
- ** Development**: We support the individual development of our employees.
- ** Fun**: From time-to-time we organise cool off-site summer and winter team events.
- ** Offices**: Our well-equipped laboratories and offices are located at the Tech Park, a premier address for early-stage start-ups in Basel.
- ** Commuter Benefits**: We support our employees tailored to their personal needs in commuting to work and offer parking facilities or a commuter contribution.
- ** Flexible Working**: We support flexible working as appropriate.
- ** Christmas Closure**: In addition to the 24 holidays per year, our offices/labs are closed between Christmas and New Year.
- ** Birthday Retreat**: On top of that, your birthday is your personal holiday - our employees enjoy their birthday with a day off.
- ** Food**: We like get-togethers during lunch time. Enjoy tasty, subsidised meals from our FELFEL food fridge.
- ** Coffee**: Meet up with your colleagues and grab free coffee.

**Job-ID**:
RLD-088

**Function**:
Scientist



  • Basel, Schweiz GITR Vollzeit

    **EINFÜHRUNG**: As a preferred supplier for Roche Basel, we are looking for an individual as **DNA-Encoded Library Screening Scientist**: with contract for 9 months, with possible extension. The earliest start date is within 3 months. Remote/Home Office possible (but mostly lab based work on-site). **AUFGABENBESCHREIBUNG**: - Conduct DNA-encoded library...


  • Basel, Schweiz CTC Resourcing Solutions Vollzeit

    **The Life Science Career Network** Our client is a pioneer in Drug Discovery and Development and one of the frontrunners in Personalised Healthcare. As the world's largest R&D spender in the pharmaceutical and diagnostics domain, they work in a vast number of drug discovery & therapeutic areas and are highly recognized internationally. We are currently...


  • Basel, Schweiz Ridgeline Discovery GmbH Vollzeit

    **Ridgeline Discovery is looking for a Scientist, Cancer Biology**. Ridgeline Discovery, a Versant Ventures Discovery Engine, creates and operates Versant-financed innovative biotech companies in partnership with entrepreneurs, industry, and leading academics across Europe. In recent years, Ridgeline has assembled an international team of \ >45 highly...


  • Basel, Schweiz Institute of Human Biology Vollzeit

    Postdoctoral fellow in Endodermal Organ BiologyRoche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share...


  • Basel, Basel-Stadt, Schweiz Gi Group SA Vollzeit

    Transformative medicines are made for patients to tackle some of the world's toughest unmet healthcare needs in Roche's Pharmaceutical Research and Early Development organization (pRED).We are seeking a creative and talented team-member to support our understanding of disease mechanisms in the Cardiometabolic, Immunology, Infectious Diseases, and...


  • Basel, Schweiz Friedrich Miescher Institute Vollzeit

    The Friedrich Miescher Institute for Biomedical Research (FMI) is a world-class research institute that investigates the molecular mechanisms of health and disease in the fields of neurobiology, genome regulation and multicellular systems. FMI research is supported by state-of-the-art core facilities, employing various cutting-edge technologies for imaging,...


  • Basel, Schweiz Institute of Human Biology Vollzeit

    Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche,...


  • Basel, Schweiz Universität Basel Vollzeit

    The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need. With more than 70 research groups and 800 employees, the...


  • Basel, Schweiz Universität Basel Vollzeit

    The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need. With more than 70 research groups and 900 employees, the...


  • Basel, Schweiz Universität Basel Vollzeit

    The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need. With more than 70 research groups and 900 employees, the...


  • Basel, Basel-Stadt, Schweiz Doris Fink Recruiting & Consulting GmbH Vollzeit

    We are seeking a motivated Senior Research Associate to join our client start-up team.About Doris Fink Recruiting & Consulting GmbHOur client is a privately held company in pharmaceutical research, focused on targeting key molecular factors involved in DNA replication stress and repair. This innovative approach offers promising opportunities for developing...

  • Scientist, Molecular

    Vor 5 Tagen


    Basel, Schweiz Ridgeline Discovery GmbH Vollzeit

    **Matterhorn Bioscience**s is looking for **a **Scientist, Molecular / Cellular Biology or Immunology**.** Matterhorn Biosciences is a preclinical stage biotechnology company pioneering the discovery and development of novel T cell therapy for cancer treatment. We are an exciting motivated group of scientists who are determined to make a difference for...

  • Scientist

    vor 19 Stunden


    Basel, Schweiz Modis Vollzeit

    We are supporting our client in finding a Scientist for their team. **Responsibilities**: - Performs Batch and Continuous Fermentation and Harvest processes according to Batch Sheet or superior’s demand in pilot scale - Performs in-process analytics independently according to guidelines - Performs calibration and maintenance of equipment **Profile**: -...


  • Basel, Schweiz Universität Basel Vollzeit

    **Postdoc position in quantitative biology (Zampieri Lab)** **Your position** - Adapting existing and possibly developing improved experimental protocols for the high-throughput metabolomics analysis of drug-perturbed cells. - Unravel the hidden potential of apparently inactive molecules in interfering with cellular metabolism. - Support and preparation of...


  • Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel Vollzeit

    IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded. We are seeking a dynamic and driven individual to join our team as...

  • Ai Research Scientist

    vor 7 Monaten


    Basel, Schweiz Panda International Vollzeit

    **AI Research Scientist**: **Location** - Basel, Switzerland **Business Sector** - AI **Job ref** - 22573 **Published** - about 14 hours ago **Key Responsibilities**: - Develop cutting-edge AI algorithms to analyze biological datasets and predict drug efficacy, safety, and pharmacokinetics. - Collaborate with a multidisciplinary team of scientists to...


  • Basel, Schweiz ITech Consult Vollzeit

    **Scientist Immunology and Cardiovascular/Metabolic Disease (M/F/d) - Pharmaceutical Research / in vitro / in vivo / data management / record-keeping / stakeholder management/ English** **Project**: For our customer a big pharmaceutical company in Basel we are looking for Scientist Immunology and Cardiovascular/Metabolic Disease (M/F/d). **Background**: At...


  • Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel Vollzeit

    The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated **Research Assistant** to join the Human Retinal Circuits Group at IOB, led by Botond Roska. The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is a research institute combining basic and clinical research. Its mission is to drive innovations in...


  • Basel, Schweiz 3Brain Vollzeit

    3Brain AG Huobstrasse 16 8808 Pfäffikon SZ Schwyz, Switzerland Field Application Scientist Job offer The Company 3Brain AG is a Swiss deep tech company working on cell-electronic interfaces that link biological networks to computers via custom-made semiconductor microchips. Our mission is to empower life scientists to probe intelligent networks,...

  • Junior Scientist

    Vor 3 Tagen


    Basel, Schweiz Batterman Consulting Basel AG Vollzeit

    **Our Client** **Junior Scientist (m/w)****: **Your responsibilites** - In close collaboration with biology/chemistry group leaders and scientists design, develop, execute and analyze a variety of experiments, including but not limited to: - RNA/DNA isolation, RT-PCR, electrophoresis, RT-qPCR for analysis of gene expression and detection of splice...