Research Associate AAV Early Supply Specialist

Vor 6 Tagen


Basel, Basel-Stadt, Schweiz Roche Vollzeit
About the Role

We are seeking a highly motivated and experienced Research Associate to join our team in the Nucleic Acid-based Medicine (NABM)-Genomic Medicine matrix organization. The successful candidate will be a member of the Applied Viral and Non-Viral Technologies (AVANT) team, responsible for producing new rAAV to supply internal research projects.

Key Responsibilities
  • Support rAAV production platform at shake-flask scale, including cell maintenance and expansion, transient transfection, and development to improve upstream processes.
  • Develop, optimize, and qualify analytical methods to assess rAAV product characterization for safety, efficacy, purity, quality, and strength.
  • Write protocols and SOPs, perform preliminary analyses, and prepare internal reports to support scientific conclusions.
  • Independently conduct analysis for in-process and final product samples to determine viral vector quality and production quality according to established SOPs.
  • Participate in trouble shooting and solving issues involved in process optimization as well as identifying critical process parameters to monitor or control to ensure the product of desired quality.
  • Development of rAAV CQAs for characterization to guide product and process development.
  • Participate in laboratory management: lab organization, ordering, equipment maintenance and qualification, etc.
Requirements
  • Scientific studies (Master (FH), alternatively Master (Univ.) or Engineer / Bachelor) with professional experience or scientific vocational training with further training as a technician and at least one year of specific work experience.
  • IT-Skills (MS Office, lab software applications), good English skills.
About Roche

At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity, and diversity.

We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.

We are committed to recognizing talent and aptitude, and prioritize encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions, and grow in their career.



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