Research Associate

vor 1 Woche


Basel, Basel-Stadt, Schweiz Roche Vollzeit

About the Role

We are seeking a highly motivated Research Associate to join our Brain Delivery group in the Neurotechnology section at the Roche Innovation Center Basel. As a key member of our team, you will be responsible for advancing cutting-edge technologies to improve the delivery of antibodies to the brain in order to develop novel therapies for neurodegenerative disorders.

Key Responsibilities

  • Maintenance of human iPSC-derived cell types of the neurovascular unit, including generation and characterization of CRISPR gene-edited lines
  • Development of cell-based assays with a broad range of microscopy and biochemical readouts
  • Design and execute experiments independently and in collaboration with other groups to advance exploratory and preclinical projects
  • Analyze, interpret and thoroughly document data. Communicate results in team and departmental meetings
  • Contribute to lab management and organization

Requirements

  • BSc/MSc in Life sciences (biology, biotechnology) or other relevant area with at least 2 years of wet lab experience
  • Strong experience with human cell culture, preferably using stem cells
  • Expertise with molecular cell biology methods including WesternBlot, ELISA, confocal microscopy, cloning and transfections
  • Hands-on experience with fluorescent or luminescent reporters and/or sensors would be beneficial
  • Basic experience with image FIJI) and data PRISM) analysis software
  • Ability to independently design, execute, and analyze experiments
  • Strong critical thinking, communication, organization, and presentation skills

Additional Requirements

  • Excellent computer-based data management and record-keeping skills; a background in basic biostatistical data analysis is a plus
  • Excellent communication skills to report your results to the team; good command of the English language is a must (speaking and writing)
  • You are a team player with a strong sense of accountability and willingness to learn
  • You must like an independent working style and troubleshooting in a multi-departmental and international pharma research environment with the motivation to build your Matrix-leadership skills

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