Senior Research Scientist in Immuno-oncology

Vor 2 Tagen


Lausanne, Waadt, Schweiz CHUV - Centre Hospitalier Universitaire Vaudois Lausanne Vollzeit

About the Role

We are seeking a highly motivated Postdoctoral Researcher to join our team at the CHUV - Centre Hospitalier Universitaire Vaudois Lausanne. As a key member of our research group, you will be working on developing novel chimeric antigen receptor (CAR) T cell therapies for the treatment of acute myeloid leukemia (AML). The successful candidate will have a strong background in immune engineering, immunology, or a related field and experience with animal models.

Key Responsibilities

  • Contribute to the development of innovative strategies implementing a new generation of CAR
  • Characterize in vitro the function of these novel CAR-T cells including immunological assays, imaging, and transcriptomics, and assess their crosstalk with AML cells
  • Validate in vivo in mouse models the anti-leukemic activity of the novel CAR-T cells and address the impact on the tumor microenvironment
  • Prepare scientific abstracts and reports for presentations
  • Participate actively in the common activities of the laboratory and our research community

Requirements

  • PhD in immune-engineering, immunology, cancer, or bioengineering
  • Solid experience and independently working with animal models (LTK1 certificate or equivalent)
  • Proficient in cell culture and gene engineering technologies
  • An independent user of multicolor flow cytometry (FACS)
  • Experience with immune synapse imaging or analysis of transcriptomics data is a plus


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