Senior Research Scientist in Immuno-oncology
Vor 2 Tagen
About the Role
We are seeking a highly motivated Postdoctoral Researcher to join our team at the CHUV - Centre Hospitalier Universitaire Vaudois Lausanne. As a key member of our research group, you will be working on developing novel chimeric antigen receptor (CAR) T cell therapies for the treatment of acute myeloid leukemia (AML). The successful candidate will have a strong background in immune engineering, immunology, or a related field and experience with animal models.
Key Responsibilities
- Contribute to the development of innovative strategies implementing a new generation of CAR
- Characterize in vitro the function of these novel CAR-T cells including immunological assays, imaging, and transcriptomics, and assess their crosstalk with AML cells
- Validate in vivo in mouse models the anti-leukemic activity of the novel CAR-T cells and address the impact on the tumor microenvironment
- Prepare scientific abstracts and reports for presentations
- Participate actively in the common activities of the laboratory and our research community
Requirements
- PhD in immune-engineering, immunology, cancer, or bioengineering
- Solid experience and independently working with animal models (LTK1 certificate or equivalent)
- Proficient in cell culture and gene engineering technologies
- An independent user of multicolor flow cytometry (FACS)
- Experience with immune synapse imaging or analysis of transcriptomics data is a plus
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