Postdoctoral Position in Tumor Immunology

vor 2 Monaten


Bern, Bern, Schweiz Kanton Bern Vollzeit
Institution: University of Bern, Institute of Tissue Medicine and Pathology Department: Experimental Pathology, Group Schenk (IP5) Location: Murtenstrasse 31, 3008 Bern, Switzerland Principal Investigator: Prof. Dr. Mirjam Schenk Duration: 24 months, with potential extension to 48 months Start Date: open now, latest start January 2025 Application Deadline: Contact Information: - Email: - Phone: The Institute of Tissue Medicine and Pathology at the University of Bern is seeking a highly motivated and self-disciplined postdoctoral researcher to join the team of Prof. M. Schenk. The successful can-didate will work on a cutting-edge project focused on the comprehensive analysis of the tumor micro-environment in pancreatic ductal adenocarcinoma (PDAC). This research aims to discover novel bi-omarkers and identify therapeutic targets to improve the diagnosis and treatment of PDAC. PDAC is an aggressive cancer with a poor prognosis and limited treatment options. This project aims to unravel the complexities of the tumor immune microenvironment using advanced imaging mass cytometry (IMC) and transcriptomic techniques (scRNA-seq and spatial transcriptomics). The integra-tion of these data with clinical parameters will facilitate the identification of key immune markers and therapeutic targets.

Postdoctoral Position in Tumor Immunology

Key Responsibilities

Conduct high-dimensional immunophenotyping of PDAC tissues using IMC.
Perform transcriptomic analyses including scRNA-seq and spatial transcriptomics.
Analyze the relationships between the immune microenvironment, tumor mutational burden, and clinical outcomes.
Design and perform in vivo experiments using murine models to assess the efficacy and mechanisms of novel treatments.
Supervise and mentor graduate and undergraduate students in the lab.
Assist in writing grant proposals and securing research funding.
Collaborate with a multidisciplinary team of researchers, clinicians, and bioinformaticians.
Prepare and present research findings at scientific conferences and in peer-reviewed journals.
Qualifications
PhD in a relevant field (e.g., Cancer Biology, Immunology).
Strong background in tumor immunology and/or cancer research.
Experience with high-dimensional data analysis, including transcriptomics and/or imaging mass cytometry.
Proficiency in bioinformatics and statistical analysis tools (e.g., R, Python).
Highly motivated and self-disciplined with excellent written and verbal communication skills in English.
Ability to work independently and as part of a collaborative team.
Preferred Qualifications:
Experience with immunology and cancer research.
Knowledge of immunotherapy and its application in cancer treatment.
Familiarity with clinical data integration and high-dimensional data analysis.
Benefits
Competitive salary and benefits package.
Access to state-of-the-art research facilities and resources.
Opportunity to work in a dynamic and collaborative research environment.
Professional development opportunities and support for career advancement.
Application Instructions
Interested candidates should submit the following documents:
A cover letter detailing research interests and relevant experience.
Curriculum vitae (CV) including a list of publications.
Contact information for three professional references.
A brief statement of research goals (1-2 pages).
Please send the application materials as a single PDF file to Prof. Dr. Mirjam Schenk at by August 31, 2024.

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