Scientist in Biopharmaceuticals

vor 2 Monaten

Basel, Basel-Stadt, Schweiz Roche Vollzeit

About the Role

We are seeking a highly motivated Scientist in Biopharmaceutics to join our team at Roche. As a member of our Biopharmaceutics Team, you will be part of a collaborative group of research associates and scientists, working together to develop advanced biopharmaceutics approaches to address formulation challenges of the future.

Key Responsibilities

  • Develop and apply state-of-the-art biopharmaceutics in vitro methods to generate mechanistic understanding of in vivo performance of standard and advanced drug delivery systems.
  • Apply in silico physiologically-based biopharmaceutics models to predict in vivo performance of oral formulations and other routes of administration.
  • Work collaboratively and cross-functionally with experts at the interface between clinical and technical development (formulation development, DS and DP analytics, DMPK, clinical pharmacology, M&S, regulatory, SM research etc.).
  • Author and review technical reports, patent applications, and parts of regulatory documents to support filings.
  • Collaborate with distinguished scientists in academia to strive for excellence in biopharmaceutics and develop new advanced technologies for absorption prediction.

Requirements

  • You hold an advanced degree in biopharmaceutics, pharmaceutical technology, or related field or with > 5 years of relevant experience in biopharmaceutics.
  • Additional experience in drug product development of oral dosage forms is an advantage.
  • You have significant experience with state-of-the-art biopharmaceutics in vitro methods for oral DP performance testing.
  • You have relevant hands-on experience with physiologically-based biopharmaceutics modeling software Gastroplus/DDDPlus, Simcyp/SIVA.
  • You have the capability to strive for excellent results and implement innovative solutions with a high level of motivation.
  • You are able to interact effectively with people, strong commitment to teamwork.
  • You have the willingness to work in a highly dynamic environment where you can bring in your creativity and continuously develop your scientific knowledge.
  • You have good communication skills with proficiency in German or English.

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