In Vitro Adme Scientist

Vor 5 Tagen

Basel, Schweiz Novartis Vollzeit

As an ADME Scientist with NIBR's Pharmacokinetic Sciences (PKS) organization, you will facilitate the ADME optimization of small molecules across discovery phases. The characterization of the absorption, distribution, metabolism, and excretion (ADME) properties using in vitro assays such as metabolic stability and cellular permeability provides critical support to discovery project teams in selecting the optimal compounds for clinical development.
The in vitro ADME group within the PKS department is seeking a highly qualified, multi-disciplinary, and team-oriented Scientist having cell biology experience with emphasis on in vitro ADME assays. In addition, a strong background in bioanalytical methods including LC/MS, radio-chromatography and PCR is desirable. In this role you will provide support for a diverse portfolio that includes small molecules as well as the beyond rule-of-5 property space. You will also be responsible for the troubleshooting and development of new ADME cell-based assays and/or running existing in vitro ADME assays to support pre-clinical project teams.

**Commitment to Diversity & Inclusion**:

- We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve._

**Minimum requirements**

**Requirements**:

- Apprenticeship, BS or MS in biology, biochemistry, analytical chemistry or related disciplines.
- A good understanding of laboratory equipment (particularly LC/MS) and associated software.
- Proficiency in cell culture work and cell-based permeability assays.
- Experience with lab automation and handing of radioactive material is desirable.
- Demonstration of strong experimental and problem-solving skills, excellent collaboration and communication skills (both written and oral), eagerness to learn, and excellent time management skills is favored.
- The ability to work in a team-based drug discovery/development environment is essential.

Why consider Novartis?
766 million. That’s how many lives our products touched in 2021 and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.
We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.
We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying Imagine what you could do here at Novartis
Imagine what you could do at Novartis

We are Novartis. Join us and help us reimagine medicine.

**Division**

Novartis Institutes for BioMedical Research

**Business Unit**

Translational Medicine

**Country**

Switzerland

**Work Location**

Basel

**Company/Legal Entity**

Novartis Pharma AG

**Functional Area**

Research & Development

**Job Type**

Full Time

**Employment Type**

Regular

**Shift Work**

No

**Early Talent**

No

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