Scientific Associate: Lcms Proteomics and
Vor 5 Tagen
**About Idorsia Pharmaceuticals Ltd**
Idorsia Ltd is reaching out for more - We have more ideas, we see more opportunities and we want to help more patients.
In order to achieve this, we want to develop Idorsia into one of Europe’s leading biopharmaceutical companies, with a strong scientific core.
Headquartered in Switzerland - a European biotech hub - Idorsia is specialized in the discovery and development of small molecules, to transform the horizon of therapeutic options. Idorsia has a broad portfolio of innovative drugs in the pipeline, an experienced team, a fully-functional research center, and a strong balance sheet - the ideal constellation to bringing R&D efforts to business success.
Idorsia was listed on the SIX Swiss Exchange (ticker symbol: IDIA) in June 2017 and has over 1,000 highly qualified specialists dedicated to realizing our ambitious targets.
We are looking for a talented and passionate Scientific Associate with extensive experience in targeted analysis of metabolites and/or proteins for the Proteomics and Metabolomics Laboratory within Idorsia’s Translational Biomarker Group (TBG).
The TBG supports Idorsia’s drug discovery and development projects across the pipeline by developing and measuring biomarkers as well as providing molecular data on drug and disease mechanisms that support clinical translation. The studies performed will include cellular and animal models, as well as clinical samples. The Proteomics and Metabolomics Laboratory is equipped with three state-of-the-art mass spectrometers and provides high-quality data to project teams on both endogenous metabolites and proteins. The lab works in close collaboration with other labs in the TBG, drug discovery, and clinical development department to obtain an integrated view of drug and disease mechanisms.
**Responsibilities**:
In this laboratory-focused role, the Scientific Associate will be responsible for the following tasks:
- Development and implementation of new protein and metabolite analysis workflows, including both sample preparation, targeted, and untargeted MS methodology
- Preparation of samples (pre-clinical and clinical) from a variety of different biological matrices (cells, solid tissues, and biofluids) for quantitative LCMS proteomic and metabolite quantification
- Analysis of targeted and untargeted quantitative LCMS datasets using commercial analysis software and R scripts
- Bioanalytical study design, in collaboration with Scientists
- Operation and maintenance of triple quadrupole and Orbitrap LC-MS/MS systems
- Actively contribute to the smooth running of the laboratory
- Proactive troubleshooting of experiments and instruments
- Keep a detailed and meticulous electronic lab journal
- Present data in Translational Biomarker team meetings
- Bachelor or Master degree (University or University of Applied Sciences) in biochemistry, chemistry, biotechnology, or appropriate related discipline
- At least 3 years relevant experience in targeted LCMS analysis of endogenous metabolites and proteins
- Knowledge and experience of protein or metabolite chemistry including some of the following: different lysis and extraction procedures (solid-phase, liquid-liquid), subcellular fractionation, metabolic labeling experiments, and tryptic digest
- Experience in development, characterization, and validation of exploratory biomarker assays for clinical studies
- Experience in working in a regulated environment would be an asset
- Well organized and proficient at running complex multi-step experiments
- Experience with the operation, maintenance, and troubleshooting of triple quadrupole mass spectrometers as well as UHPLC and nano-flow liquid chromatography
- Understanding of experimental design and basic statistical knowledge
- A strong passion for bioanalytics, mass spectrometry, translational science and drug discovery and a willingness to explore new areas
- Team player, at ease interacting in a multicultural environment
- Proficient in the English language, German and/or French would be an advantage
**What Idorsia offers**
- Exciting opportunities for development and professional growth within our dynamic organization
- A collaborative and solution-oriented environment where you can make a difference
- An innovative and open culture in a truly multicultural environment
- A competitive salary and generous social benefits
**Work Location**: Allschwil - Basel Area
**Country**:Switzerland
**Business Area**:Drug Discovery Biology - Translational Biomarkers
**Schedule**: Fulltime
**Job Type**: Permanent
**Job ID**:3248
**Job Types**: Full-time, Permanent
-
Associate Director Global Scientific Affairs
Vor 3 Tagen
Basel, Schweiz Sobi Vollzeit**Sobi offers the opportunity to work at an international pharmaceutical company focused on specialty pharmaceuticals meeting the high medical needs of rare disease patients and providing treatment and services to them. Our employees come from a variety of backgrounds within research, healthcare, industry and the academic sphere.** **Associate Director...
-
Temporary Assistant Scientific Associate
Vor 5 Tagen
Basel, Schweiz Idorsia Pharmaceuticals Ltd. Vollzeit**About Idorsia Pharmaceuticals Ltd** Idorsia Ltd is reaching out for more - We have more ideas, we see more opportunities and we want to help more patients. In order to achieve this, we want to develop Idorsia into one of Europe’s leading biopharmaceutical companies, with a strong scientific core. Headquartered in Switzerland - a European biotech hub -...
-
Compound and Process Manager, Automation and
Vor 5 Tagen
Basel, Schweiz Monte Rosa Therapeutics, Inc VollzeitOverview: Monte Rosa Therapeutics is seeking a highly skilled Expert in Automation and Compound Management in our Basel office. The position will implement automation projects for our sample management workflows and support basic compound management functions. **Responsibilities**: - Establish and maintain new automated workflows for management of...
-
Associate Director of Global Scientific Affairs
vor 9 Stunden
Basel, Schweiz Hobson Prior VollzeitHobson Prior are seeking an Associate Director of Global Scientific Affairs for a fantastic pharmaceutical establishment on a permanent basis. Our client is focused on manufacturing novel remedies for people with unique illnesses. Please note that to be considered for this role you must have the right to work in this location. **Key Responsibilities**: -...
-
Project Support Associate
vor 1 Woche
Basel, Schweiz Thermo Fisher Scientific VollzeitThermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue of approximately $40 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving complex analytical challenges, increasing productivity in their laboratories,...
-
Scientific Associate
vor 1 Woche
Basel, Schweiz CTC Resourcing Solutions Vollzeit**The Life Science Career Network** Our client is a leading global player in the Pharmaceutical industry with global headquarters in Basel, Switzerland. The organisation focusses on novel therapies in Oncology and Ophthalmology and is also currently developing a world-leading pipeline in Neuroscience and Dermatology with one of the strongest pipelines of...
-
Scientific Associate
Vor 7 Tagen
Basel, Schweiz CTC Resourcing Solutions Vollzeit**The Life Science Career Network** Our client is a leading global player in the Pharmaceutical industry with global headquarters in Basel, Switzerland. The organisation focusses on novel therapies in Oncology and Ophthalmology and is also currently developing a world-leading pipeline in Neuroscience and Dermatology with one of the strongest pipelines of...
-
Project Support Associate Distribution
Vor 4 Tagen
Basel, Schweiz Thermo Fisher Scientific VollzeitOur team of colleagues in clinical research services are at the forefront of getting cures to market. We bring a high caliber of scientific and clinical expertise to the development of drugs that address the world’s most challenging health concerns. Our Clinical Research team, who powers our PPD® clinical research portfolio, are part of our leading global...
-
Project Support Associate Distribution
Vor 5 Tagen
Basel, Schweiz Thermo Fisher Scientific VollzeitThermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue of approximately $50 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving sophisticated analytical challenges, growing efficiency in their laboratories,...
-
Project Support Associate
Vor 5 Tagen
Basel, Schweiz Thermo Fisher Scientific Vollzeit**Project Support Associate** Division: Clinical Trial Division (CTD) **Position summary**: The Project Support Associate provides administrative support to Project Managers for successful completion and supply maintenance over the life cycle of each project. Project support activities include task completion and issue resolution with internal customer...
-
Scientific Associate Adqc
Vor 6 Tagen
Basel, Schweiz CTC Resourcing Solutions VollzeitThe Life Science Career Network Our client, an innovative Swiss bio-pharmaceutical company, is seeking an **Scientific Associate in Analytical Development** for a 12-month contract in the Basel area. **Main Responsibilities**: - content-and potentially genotoxic impurity determinations. - Write-up of analytical methods for implementation. - Conduct of...
-
Administrative Support
Vor 3 Tagen
Basel, Schweiz Thermo Fisher Scientific VollzeitWhen you’re part of the team at Thermo Fisher Scientific, you’ll do important work, like helping customers in finding cures for cancer, protecting the environment or making sure our food is safe. Your work will have real-world impact, and you’ll be supported in achieving your career goals. **Administrative support - Project Support...
-
Research Technician
Vor 5 Tagen
Basel, Schweiz Idorsia Pharmaceuticals Ltd. Vollzeit**About Idorsia Pharmaceuticals Ltd** Idorsia Ltd is reaching out for more - We have more ideas, we see more opportunities and we want to help more patients. In order to achieve this, we want to develop Idorsia into one of Europe’s leading biopharmaceutical companies, with a strong scientific core. Headquartered in Switzerland - a European biotech hub -...
-
Associate Project Manager
Vor 3 Tagen
Basel, Schweiz Thermo Fisher Scientific VollzeitOur team of colleagues in clinical research services are at the forefront of getting cures to market. We bring a high caliber of scientific and clinical expertise to the development of drugs that address the world’s most challenging health concerns. Our Clinical Research team, who powers our PPD® clinical research portfolio, are part of our leading global...
-
Basel, Schweiz Thermo Fisher Scientific VollzeitOur team of colleagues in clinical research services are at the forefront of getting cures to market. We bring a high caliber of scientific and clinical expertise to the development of drugs that address the world’s most challenging health concerns. Our Clinical Research team, who powers our PPD® clinical research portfolio, are part of our leading global...
-
Associate Project Manager
Vor 5 Tagen
Basel, Schweiz Thermo Fisher Scientific VollzeitThermo Fisher Scientific Inc. is the world leader in serving science, with annual revenue of approximately $50 billion. Our Mission is to enable our customers to make the world healthier, cleaner and safer. Whether our customers are accelerating life sciences research, solving sophisticated analytical challenges, growing efficiency in their laboratories,...
-
Clinical Research Associate Ii/ Cra Ii
vor 1 Woche
Basel, Schweiz Thermo Fisher Scientific VollzeitAt Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through...
-
Clinical Research Associate Ii/ Cra Ii
Vor 7 Tagen
Basel, Schweiz Thermo Fisher Scientific VollzeitAt Thermo Fisher Scientific, you’ll discover meaningful work that makes a positive impact on a global scale. Join our colleagues in bringing our Mission to life - enabling our customers to make the world healthier, cleaner and safer. We provide our teams with the resources needed to achieve individual career goals while taking science a step beyond through...
-
Project Support Associate Distribution
vor 9 Stunden
Basel, Schweiz Thermo Fisher Scientific VollzeitWhen you’re part of Thermo Fisher Scientific, you’ll do challenging work, and be part of a team that values performance, quality and innovation. As part of a successful, growing global organization you will be encouraged to perform at your best. With revenues of $40 billion and the largest investment in R&D in the industry, we give our people the...
-
Scientific Associate
vor 1 Tag
Basel, Schweiz Idorsia Pharmaceuticals Ltd. Vollzeit**About Idorsia Pharmaceuticals Ltd** Idorsia Ltd is reaching out for more - We have more ideas, we see more opportunities and we want to help more patients. In order to achieve this, we want to develop Idorsia into one of Europe’s leading biopharmaceutical companies, with a strong scientific core. Headquartered in Switzerland - a European biotech hub -...
