Research Associate in vitro and cellular compound profiling in Targeted Protein Degradation

SERAC Biosciences AG is looking for a Research Associate in vitro and cellular compound profiling in Targeted Protein Degradation.Ridgeline Discovery, a Versant Ventures Discovery Engine, creates and operates Versant-financed innovative biotech companies in partnership with entrepreneurs, industry, and leading academics across Europe. In recent years, Ridgeline has assembled an international team of >50 highly experienced drug discovery and industry professionals and built and operated multiple new successful companies; these companies have raised significant funds through Series B, IPO and an exit through a trade sale.Join our Basel-based portfolio company Serac Biosciences AG as a motivated Research Associate and become an enthusiastic team player in a fast-paced start-up environment, where you can make a real impact in a vibrant and agile biotech setting.   Key RESPONSIBILITIESSupport both routine research activities and more in-depth profiling studies by performing cell-based and biochemical/biophysical studies to assist with the identification, validation, prioritization and benchmarking of small molecule protein degraders.Perform a wide variety of medium- to high-throughput profiling workflows with cell-based and biochemical formats.Streamline operation and processes using semi- or full automation to meet timelines and team objectives.Independently design, conduct, and summarize data for key experiments to progress projects. Troubleshoot and implement solutions when required.Maintain thorough documentation and written records of experimental and data in lab notebooks and communicate results in a clear/concise manner in internal meetings.Contribute to laboratory general organization and maintenance, manage laboratory stocks and ordering.Ensure compliance with good laboratory practices including safety regulations, data management, data recording in electronic notebooks and archiving.Keen interest in understanding the current literature surrounding TPD and specific targets of interest.QUALIFICATIONSBachelor's/master's degree in biology/cell-biology (focus on small molecule profiling), biochemistry/biophysics/biotechnology (with cell-biology experience), or related field. This position is not suitable for PhD level or above.Or laboratory apprenticeship with 2+ years relevant drug discovery experience in biotech or pharma.Experience with basic techniques related to biochemistry, biophysics and small molecule handling required, e.g. FP, TSA, SPR.Experience with basic techniques related to mammalian cell-culture and assays required, e.g. BRET, Western Blot, ELISA, IP.Experience with FACS considered a plus.Working experience in targeted protein degradation (molecular glue, PROTACs and related) considered a plus.Must be able to work well in a highly collaborative team-oriented environment. Capable of thriving and multi-tasking in a fast-paced "start-up" environment.Self-motivated, willingness to learn, strong work ethic, attention to detail, organizational skills, and excellent communication skills are required for this position.Proficiency in utilizing general and specialized software such as Microsoft office, Prism, ELN etc., for data analysis and figure generation.Fluency in English required. WHAT WE CURRENTLY OFFEROffices: Our well-equipped laboratories and offices are located at the Tech Park, a premier address for early-stage start-ups in Basel.Commuter Benefits: We support our employees tailored to their personal needs in commuting to work and offer parking facilities or a commuter contribution.Flexible Working: We support flexible working as appropriate.Christmas Closure: In addition to the 24 holidays per year, our offices/labs are closed between Christmas and New Year.Birthday Retreat: On top of that, your birthday is your personal holiday - our employees enjoy their birthday with a day off.Food: We like get-togethers during lunch time. Enjoy tasty, subsidised meals from our FELFEL food fridge.Coffee: Meet up with your colleagues and grab free coffee.Development: We support the individual development of our employees.Creativity: We offer an innovative and creative environment.People: We are an international and diverse team with talented and passionate people.Fun: From time-to-time we organise cool off-site summer and winter team events.Please send us your CV and Cover letter until December 18th, 2025. Job-ID: SRB-004   Function: Associate