Postdoctoral Fellow, Gene and Cell Therapy

vor 2 Wochen

Schlieren, Zürich, Schweiz Universität Zürich Vollzeit CHF 60'000 - CHF 80'000 pro Jahr

Institute for Regenerative Medicine

Postdoctoral Fellow, Gene and Cell Therapy %

Start of employment , temporary

We are seeking an experienced postdoctoral researcher for developing and preclinical testing of innovative cell and gene therapy. Our laboratory is established at the Institute for Regenerative Medicine (IREM, ), a leading research institute of the University of Zurich (UZH) at the life-science research campus in Schlieren (ZH). We have a long-standing track record of gene therapy bench-to-bedside development for inherited diseases.

Based on bio-inspired principles and novel biomimetic technologies, IREM research focuses on the replacement and/or regeneration of dysfunctional human cells, tissues or organs to restore or establish physiological functions. Thematic priorities are translational regenerative technologies, cell-based regeneration and biomimetic tissue replacement, gene and cell therapy, stem cell biology and cancer, and translational neuroregeneration.

Your responsibilities

Our laboratory is developing and translating viral and genome editing gene therapy systems for treating patients with severe, often fatal diseases of the blood, immune and central nervous system. Our research is based on interdisciplinary and dynamic collaborations within a team of young international scientists and clinicians. You will profit from personal development possibilities and our strong vocational training culture. The salary is in the range recommended by the Swiss National Science Foundation.

  • You will extend our portfolio of gene therapy tools to address phagocyte-related diseases by developing novel in vivo gene therapy approaches targeting hematopoietic stem cells.
  • You will generate data on efficacy and safety of gene therapy vectors in multiple target cells and carry on preclinical development to animal models towards clinical application in patients.
  • Your skills and research experience will allow you to successfully publish your results and obtain competitive external funding.
  • As a senior member of the team, you will coordinate tasks across multiple projects and contribute to the supervision of master and doctoral students.
  • Habilitation and later creation of your own research group are encouraged.
Your profile
  • You are an enthusiastic and creative scientist, interested to work in a collaborative, multidisciplinary team, striving to further scientific discovery towards clinical applications.
  • You hold a doctoral degree (PhD, or MD/PhD) in molecular biology, biomedicine, immunology, or other relevant fields with excellent qualifications, documented by at least 3 years of research experience and publications in international journals.
  • You have hands-on experience with lentiviral vectors and gene editing tools, as well as extensive knowledge in hematopoietic stem cell and phagocyte biology and DNA repair mechanism.
  • Furthermore, experience in primary human cell cultures, multicolor flow cytometry, qPCR/ddPCR, transgenic mouse models and next generation sequencing technologies would be of advantage.
  • FELASA/LTK-1 accreditation is required.
Information on your application

Please submit your application online as a single PDF file (including statement on scientific background and interests, CV/publication list, copies of academic certificates, and contact information of at least two references).

What we offer

Work-Life Balance

  • Flexible working models (such as part-time positions, mobile working, job-sharing)
  • Childcare at the kihz foundation of UZH and ETH

Learning and Development

  • Wide range of continuing education courses of UZH and the Canton of Zurich
  • Language Center run jointly with ETH Zurich

Food

  • Food and drinks at reduced prices in the UZH cafeterias
  • Lunch-Check-card with UZH contribution

Healthcare

  • Special conditions on the Academic Sports Association ASVZ
  • Free seasonal flu vaccinations
  • Rest and relaxation at the quiet room in the university tower

Discounts

  • Private traffic: Carsharing, rent a vehicle, parking space
  • Digitalization: Hardware, software, mobile phone subscriptions
  • Special conditions on hotel reservations

Conditions of Employment

  • Policies of the UZH
  • Most UZH staff are employed according to public law

International Services

  • Support for people from outside Switzerland

Campuses

  • Campuses Zurich City, Zurich Irchel, Oerlikon and Schlieren
  • Sites Zurich West, Old Botanical Garden, Botanical Garden and Lengg
Location
Institute for Regenerative Medicine

Wagistrasse 12, 8952 Schlieren, Switzerland

Further information
Questions about the job

Ute Modlich, PhD

Scientific Head Gene- and Cell Therapy

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The University of Zurich, Switzerland's largest university, offers a range of attractive positions in various subject areas and professional fields. With around 10,000 employees and currently 12 professional apprenticeship streams the University offers an inspiring working environment on cutting-edge research and top-class education. Put your talent and skills to work with us. Find out more about UZH as an employer

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