Lab Scientist in Functional Proteomics
Vor 7 Tagen
We are seeking a highly motivated and experienced Lab Scientist to join our team in Functional Proteomics at Roche. As a key member of our team, you will be responsible for designing, executing, and analyzing experiments to interrogate the proteome for functional characterization of disease biology, model system characterization, and identification of target and drug mechanisms.
Key Responsibilities- Plan, design, execute, and analyze hands-on experiments to interrogate the proteome for functional characterization of disease biology, model system characterization, and identification of target and drug mechanisms.
- Develop, optimize, and implement standard or customized LC-MS proteomics workflows, including sample preparation, nano LC-MS/MS measurement using high-end mass spectrometry, and data QC and processing.
- Apply scientific rigor to optimize newly implemented and/or developed proteomics workflows to ensure high-quality FAIR data generation, collaborate with other laboratory and bioinformatics teams to analyze and interpret LC-MS-based proteomics data, be accountable for the timely generation of comprehensive project reports, and engage with stakeholders to present and discuss findings in a dynamic and flexible manner.
- Embrace a continuous learning mindset by actively engaging with the scientific literature to stay abreast of emergent technologies/approaches in the proteomics field.
- You have a PhD degree in Biology, Biochemistry, Chemistry, or a related field, with 3-5 years of proteomics research experience, preferably within either the biotechnology or pharmaceutical industry.
- You are a skilled experimentalist with the aptitude to design complex studies including quantitative and affinity enrichment-based proteomics workflows to study protein abundance, activation state, localization, and interactions.
- You have exceptional competency in the processing, analysis, and interpretation of advanced proteomics datastreams, with the ability to integrate with other OMICS technologies being considered a plus.
At Roche, we are committed to recognizing talent and aptitude. We prioritize encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions, and grow in their career. We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.
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