Neuropathology Research Director
vor 4 Wochen
About the Role
We are seeking a highly skilled and experienced Neuropathology expert to lead our research team in the Neuroscience and Rare Disease therapeutic area. As a key member of our team, you will be responsible for understanding and quantifying neurodegenerative disease pathology in animal models and human post-mortem tissues and biofluids.
Key Responsibilities
- Recruit and lead an effective team to understand pathology of neurodegenerative diseases at the cellular level by performing quantitative histopathology, spatial omics, and related experiments.
- Contribute to multiple projects by bringing deep scientific expertise about the pathology-relevant microenvironment and how different cell types influence each other during the neurodegenerative process.
- Generate ideas for back translation from clinical trial samples and data to target and/or biomarker identification.
- Interface with omics and in vivo and in vitro models colleagues to design and interpret experiments.
- Lead drug discovery projects related to neurodegenerative disorders.
Requirements
- PhD or MD/PhD in neuroscience or cellular biology with minimum 5 years of experience in Neuropathology.
- Rigorous scientist with a deep understanding and practical experience in cellular neuroscience, including major neural cell type histology in preclinical disease rodent/larger mammal models and post-mortem patient samples.
- Expertise in neurodegenerative diseases such as Alzheimer's, Parkinson's, ALS, and/or Multiple Sclerosis, including a solid grasp of the literature in neurodegeneration.
- Experience using multi-omics approaches such as proteomics, transcriptomics, and/or single cell genomics to quantify differences in disease state, with experience integrating two or more of these omics approaches a plus.
- Proven scientific-track record through impactful publications in relevant fields, patents, or substantial contributions to drug development programs.
- Driven by the desire to find therapeutics for some of the most complicated and devastating disorders.
- Enjoy teamwork, diligence, and efficiency. Kind and influential team leader and trusted and knowledgeable colleague.
- Working in a multicultural environment motivates you.
About Roche
Roche commits to recognizing talent and aptitude. We prioritize encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions, and grow in their career.
We are confident that we find the most innovative solutions by gaining different perspectives, asking and answering hard questions, and challenging the status quo. Roche embraces diversity and equal opportunity in a serious yet enthusiastic way; we are devoted to building a team that represents a range of backgrounds, perspectives, and skills. The more inclusive we are, the better our work will be.
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