Internship in Crystallization and Solid-State Characterization

Vor 7 Tagen


Basel, Basel-Stadt, Schweiz Roche Vollzeit

About the Position

As a member of the global technical development organization, the Particle Design group is the center of excellence for the design of drug substance particles with tailor-made solid-state properties to facilitate downstream processing to the drug product. This includes the development and optimization of the processes on laboratory scale, as well as scale-up of the corresponding manufacturing processes in close collaboration with the production sites. Our responsibilities also include the evaluation and implementation of new strategies to obtain particles with the desired properties.

Project Overview

The Particle Design group is seeking an intern to work on the project area of Ab-initio solubility prediction enhanced by machine learning. The intern will be responsible for improving the already established workflow for the solubility computation by a machine-learning module. This includes an experimental part (70% laboratory work including sample preparation, solubility measurements and solid residue analysis) as well as a computational part: The remaining 30% will be dedicated to data preparation, model training and evaluation of different machine learning models.

Responsibilities

  • Conduct laboratory experiments to measure solubility and solid residue analysis
  • Prepare and analyze data for machine learning model training
  • Develop and implement machine learning models to improve solubility prediction
  • Collaborate with the production sites to scale-up manufacturing processes

Requirements

  • Enrolled student in chemistry, chemical or process engineering, pharmacy, pharmaceutical sciences, pharmaceutical technology, physics or a related field
  • Good knowledge of MS-Office and Google equivalents
  • Proficient in English, German is a plus
  • Experience working in a lab-environment
  • Good knowledge of python programming and machine learning libraries

What We Offer

  • A dynamic and collaborative work environment
  • Opportunities for professional growth and development
  • A competitive internship stipend

How to Apply

Please submit your application, including a current CV and a motivation letter, to [insert contact information]. We look forward to hearing from you



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