Scientist in Biopharmaceutics Specialist

vor 3 Wochen


Basel, Basel-Stadt, Schweiz Roche Vollzeit
The Position

Scientist in Biopharmaceutics (temporary contract for 3 years)

At Roche, we are committed to delivering medical solutions that make a meaningful difference in patients' lives. We believe in the importance of scientific rigor, unassailable ethics, and access to medical innovations for all. As a member of our Biopharmaceutics Team, you will be part of a collaborative group of research associates and scientists who are passionate about transforming patients' lives.

The position is part of the Biopharmaceutics Team in the Synthetic Molecules Drug Product Development organization. As a member of this team, you will be responsible for providing fundamental understanding of in vivo drug product performance and defining adequate biopharmaceutics strategies at all stages of clinical development.

Key Responsibilities
  1. Develop and apply state-of-the-art biopharmaceutics in vitro methods to generate mechanistic understanding of in vivo performance of standard and advanced drug delivery systems.
  2. Apply in silico physiologically-based biopharmaceutics models to predict in vivo performance of oral formulations and other routes of administration.
  3. Work collaboratively and cross-functionally with experts at the interface between clinical and technical development.
  4. Author and review technical reports, patent applications, and parts of regulatory documents to support filings.
  5. Collaborate with distinguished scientists in academia to strive for excellence in biopharmaceutics and develop new advanced technologies for absorption prediction.
Requirements

You must have an advanced degree in biopharmaceutics, pharmaceutical technology, or a related field, or more than 5 years of relevant experience in biopharmaceutics. Additional experience in drug product development of oral dosage forms is an advantage. You must also have significant experience with state-of-the-art biopharmaceutics in vitro methods for oral DP performance testing and relevant hands-on experience with physiologically-based biopharmaceutics modeling software Gastroplus/DDDPlus, Simcyp/SIVA.

You must be able to interact effectively with people, have a strong commitment to teamwork, and be willing to work in a highly dynamic environment where you can bring in your creativity and continuously develop your scientific knowledge. Good communication skills with proficiency in German or English are also required.



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