Biomarker Experimental Medicine Lead

Vor 6 Tagen


Basel, Basel-Stadt, Schweiz Roche Vollzeit

About the Role

We are seeking a highly experienced Biomarker Experimental Medicine Lead to join our Translational Medicine Group in the Ophthalmology department. As a key member of our team, you will be responsible for developing and implementing forward and reverse translational biomarker strategies during pre-clinical and clinical phases of individual drug development programs or research collaborations.

Key Responsibilities

  • Develop and implement biomarker-related activities for quantifying drug response and selecting patients for personalized healthcare.
  • Lead the BioX Expert Team as a Matrix Leader and collaborate with academic, industry, internal, and external experts in biomarker, experimental medicine, and natural history studies.
  • Provide scientific and strategic input into overall drug and clinical development plans and ensure that biomarker-related activities are fit-for-purpose and drive decision-making.

Requirements

  • PhD and/or MD degree with at least 8-10 years of prior relevant experience in research, industry, or clinical settings, supported by a strong publication record or equivalent contributions.
  • At least 5 years of exposure to translational and/or clinical development of biomarkers, including protein, metabolites, genetic, imaging, and functional biomarkers, in the context of pharmaceutical industry either in research or clinical settings.
  • Strong leadership skills, with the ability to lead cross-functional matrix teams, drive team decisions, and prioritize work to focus on individual goals and team deliverables.
  • Good understanding of methodological and bioanalytical approaches and the ability to generate, integrate, and interpret pre-clinical, clinical, and drug development data to enable proof of biology, dose selection, and safety across clinical programs.

Preferred Qualifications

  • Prior experience in Ophthalmology is a valuable asset.

About Roche

At Roche, we are committed to recognizing talent and aptitude. We prioritize encouraging and supporting our employees on their personal journeys by providing a safe, creative space to help them reflect, make decisions, and grow in their career. We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.



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