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Postgraduate in Aav Producer Cell Line Engineering

vor 3 Monaten


Basel, Schweiz Novartis Vollzeit

387985BR

**Postgraduate in AAV Producer cell line engineering**:
Switzerland

**About the role**

We are looking for a highly motivated intern who recently received a M.Sc. degree with a strong scientific drive and interest in cell culture technologies & gene therapy. The intern will advance our adeno-associated viral vectors (AAV) manufacturing platform using cell line engineering tools.
Preferred start date: February - March 2024
Duration: 10 months
Key responsibilities:

- Perform state-of-the-art HEK (stable) cell line engineering/generation activities to boost AAV titers by utilizing cutting-edge gene editing & RNAi technologies
- Evaluate and improve essential components for the production of AAVs
- Execute AAV productions and determine quality by ddPCR, Western Blot and ELISA
- Support cell & molecular biology characterization of engineered cell lines using appropriate methods such as flow cytometry, NGS & qPCR
- Document experiments using electronic lab book and according to line function requirements
- Analyze and collect experimental data & present scientific interpretation in internal meetings

**Commitment to Diversity & Inclusion**:

- We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve._

**Role Requirements**
- Recent Master graduate (up to 6 months) with a degree in Biotechnology, Biology, Bioengineering, Biochemistry or similar
- Proficient in English (written and spoken)
- Experience in cell culture, desirable HEK (suspension) cell culture
- Excellent team player

Desirable requirements:

- Good experience in the production of adeno-associated viruses (AAVs) is of advantage
- Experience in ddPCR, ELISA, gene editing techniques, RNAi and FACS is of advantage

Accessibility and accommodation

Novartis is committed to working with and providing reasonable accommodation to all

individuals. If, because of a medical condition or disability, you need a reasonable

accommodation for any part of the recruitment process, or in order to receive more detailed

contact information. Please include the job requisition number in your message

**Division**

Biomedical Research

**Business Unit**

BIOLOGICS NIBR

**Work Location**

Basel

**Company/Legal Entity**

Novartis Pharma AG

**Functional Area**

Interns/Students on Novartis Payroll

**Job Type**

Full Time

**Employment Type**

Internship

**Shift Work**

No

**Early Talent**

Yes