Laboratory Technician, in Vivo
vor 1 Woche
NBE Therapeutics is a subsidiary of the Boehringer Ingelheim group: a perfect symbiosis between a rapidly growing biotechnology company and an already well established big pharma. We are located in Basel, a Swiss city on the river Rhine, known for being an important center of chemical and pharmaceutical industries but also renowned for its versatile cultural aspects - a great place to live and work. Our Research Team is committed to the development of next generation antibody drug conjugates for the treatment of cancer. We are looking for a highly motivated:
**Laboratory Technician,**_in vivo (M/F/d, 100%)_**
**Your tasks**
- Perform _in vivo_ experimental models of cancer in mice, including:
- Delivery of drug compounds and cells using various routes of administration (IV, PO, SC, IV, IP)
- Assessment of animal health throughout the study (health checks, clinical observations)
- Periodic measurements of bodyweights and tumors
- Harvest and preparation of tumor samples
- _Ex vivo _processing of_ in vivo _material (e.g. with gentleMACS dissociator)
- Development and validation of new animal models, and _ex-vivo_ and _in-vitro_ assays according to the need of the department
- Skilled in basic _in vitro_ techniques such as FACS, ELISA, Western-Blot, cell culture assays
- Independent planning, execution documentation of experiments and interpretation of results
- Review relevant literature to optimize experimental methods, stimulate new ideas and develop new assays for experimental studies
- Presentation of results within a multidisciplinary team environment
- Contribute to the general lab infrastructure, including ordering of consumables, and coordinating with colleagues the workflow, organization, maintenance, and function of lab resource
**Your Profile**
- Work experience and knowledge of preclinical _in vivo_ models
- Officially recognized as animal experimenter (LTK1 or equivalent) by the Federal Veterinary Office
- Practical background in different _in vitro_ techniques (FACS, ELISA, primary cell culture handling, SDS-PAGE, Western blot)
- Flexible person and keen to learn new skills and techniques
- Ability to work independently, flexibility with regard to working-hours and ability to accommodate changing priorities, timelines or tasks
- Good oral and written communication skills in English; additional knowledge of German preferred
- Well trained in computer programs: Excel, Power Point, Word, GraphPad Prism, FlowJo
**What we offer**
- Exciting opportunities for development and professional growth within our dynamic organization
- An opportunity to make a difference on the way to safe peoples life
- An innovative and open culture in a diverse and young environment
**Who We Are and Our Culture**
NBE-Therapeutics is an equal opportunity employer who takes pride in maintaining a diverse and inclusive culture. We embrace diversity of perspectives and strive for an inclusive environment, which benefits our employees, patients and communities.
In January 2021, NBE-Therapeutics joined as a subsidiary specialized in ADCs, the Boehringer Ingelheim group, which focuses on innovative medicines for people and animals since more than 130 years. Boehringer Ingelheim is one of the pharmaceutical industry’s top 20 companies and to this day remains family-owned. Day by day, more than 53’000 employees create value through innovation for the three business areas human pharmaceuticals, animal health and biopharmaceutical contract manufacturing. In 2023, Boehringer Ingelheim achieved a total revenue of nearly 25.6 billion euros. R&D investments, exceeding 5.8 billion euros, corresponded to 22.5% of net sales.
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