(Proteomics/metabolomics-) Data Scientist

Vor 5 Tagen


Basel, Schweiz Idorsia Pharmaceuticals Ltd. Vollzeit

**About Idorsia Pharmaceuticals Ltd**

Idorsia Ltd is reaching out for more - We have more ideas, we see more opportunities and we want to help more patients.
In order to achieve this, we want to develop Idorsia into one of Europe’s leading biopharmaceutical companies, with a strong scientific core.
Headquartered in Switzerland - a European biotech hub - Idorsia is specialized in the discovery and development of small molecules, to transform the horizon of therapeutic options. Idorsia has a broad portfolio of innovative drugs in the pipeline, an experienced team, a fully-functional research center, and a strong balance sheet - the ideal constellation to bringing R&D efforts to business success.
Idorsia was listed on the SIX Swiss Exchange (ticker symbol: IDIA) in June 2017 and has over 1,000 highly qualified specialists dedicated to realizing our ambitious targets.

**Responsibilities**:
As a Data Scientist in the Translational Biomarker Group you will be responsible for analyzing and integrating complex data sets obtained through in-house experiments and/or retrieved from external sources with the goal to provide actionable conclusions for the drug development projects. For this position, we are looking for a person experienced in the analysis of various types of biomedical data with a particular focus on proteomic and metabolomic data analyses.

The Translational Biomarker Group scientifically and experimentally engages in discovery and early clinical development teams to solve project-related questions. As the representative of the Translational Biomarker Group, you will be working closely together with various stakeholders to perform analyses and discuss the results within interdisciplinary drug development project teams.

The Data Scientist will be responsible for:

- Drive the exploration and validation of novel drug targets, mechanisms and (disease) biomarkers
- Continuous improvement of analytical strategies, evaluation, validation and implementation of new tools and methodologies
- Drive the proteomic and metabolomic data science activities (in close collaboration with the LC-MS lab)
- Liaise with drug discovery teams on experimental design and strategies for preclinical and clinical studies
- Document, report and effectively communicate project context and results with team members in the Translational Biomarker group and therapeutic area groups
- Represent the Translational Biomarker group in multidisciplinary drug development project teams
- Publish, present, and discuss scientific results at international meetings; be a representative of the Biomarker strategy in Idorsia towards an international expert audience
- Develop and constantly innovate the Translational Biomarker strategy for Idorsia
- PhD in bioinformatics or any other relevant life sciences discipline with demonstrated experience in complex data analysis of omics data sets
- At least 3 years of experience in drug discovery and development, ideally in an industry setting
- Strong experience with the processing and biological interpretation of mass spectrometry-based untargeted proteomic and/or metabolomic data
- Knowledge on advantages and limitations of different mass spectrometry-based acquisition approaches (DDA, DIA, metabolic labeling, TMT)
- Demonstrated ability to test and/or develop new computational tools to draw relevant biological insight from omics data with respect to target validation, compound mode of action and translatable biomarkers
- Expert knowledge in omics information resources and more advanced pathway / biological network analysis as well as cross-omics integrative analyses
- Experience in one or more therapeutic areas of interest to Idorsia (CNS, Immunology, Oncology, and CV/fibrosis) would be an advantage
- Demonstrated experience of working in multicultural, multidisciplinary and matrix environments
- Result oriented, problem-solver with a good understanding of biology in multiple therapeutic areas preferably with experience in a medical setting
- Background in computational analysis, experienced in statistical analysis with good scripting and programming skills (e.g. shell, R, Python)
- Dynamic team player with excellent communication and networking skills, flexible mindset and scientifically curious
- Full professional proficiency in English
**What Idorsia offers**
- Exciting opportunities for development and professional growth within our dynamic organization
- A collaborative and solution-oriented environment where you can make a difference
- An innovative and open culture in a truly multicultural environment
- A competitive salary and generous social benefits
**Work Location**: Allschwil - Basel Area
**Country**: Switzerland
**Business Area**: Drug Discovery Biology - Translational Biomarkers
**Schedule**: Fulltime

**Job Type**:Permanent
**Job ID**:3247

**Job Types**: Full-time, Permanent


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