Scientist, Cell Line Engineering and Screening

Vor 4 Tagen


Basel, Schweiz Ridgeline Discovery GmbH Vollzeit

**RESPONSIBILITIES**
- Design and execution of cell-based screening using High-Throughput (HT) flow cytometry
- Generate robust mammalian cell lines for bioassays
- Perform all duties related to CLD conducted in the laboratory, including experimental study design, planning, execution, analysis, and writing of technical reports
- Responsible for problem-solving and the development of innovative and pragmatic solutions to scientific and technical challenges
- Conduct training and support of Research Associates and Interns
- Participate in multiple simultaneous projects
- Evaluate new equipment and lead the establishment of new SOPs (flow-based screening, liquid handling procedures, etc.)
- Support lab automation or single cell imaging efforts as required
- Present scientific data internally to team members, e.g., at project team meetings, and possibly to upper management

**QUALIFICATIONS**
- M.Sc. in Biotechnology, Biochemistry, or related discipline with 5+ years of practical experience in cellular screenings and cell line engineering or PhD degree
- Practical experience with Flow Cytometric Analysis is mandatory
- Hands-on experience with genome manipulation (CRISPR/Recombinase)
- Confident in vector design and sequence verification
- Experience in basic lab automation DNA sequence analysis is a strong plus
- Practical experience with mammalian cell line development including single cell cloning, HT screening techniques, surface-marker quantification or (adeno-)viral particle quantification are a strong asset
- Highly precise and organized working style with good scientific documentation and communication skills
- Proficiency in both written and spoken English
- Must be highly independent, able to work in a fast-growing and highly diverse international team and thrive in a “start-up” environment
- Good computer skills required (MS Office, Apple hardware)
- Experience with electronic lab notebook, molecular biology software, data analysis software, or other laboratory software a plus

**WHAT WE CURRENTLY OFFER**
- **Offices**: Our well-equipped laboratories and offices are located at the Technologiepark, a premier address for early-stage start-ups in Basel.
- **Commuter Benefits**:We support our employees tailored to their personal needs in commuting to work and offer parking facilities or a commuter contribution.
- Flexible Working: We support flexible working as appropriate.
- **Christmas Closure**:In addition to the 24 holidays per year, our offices/labs are closed between Christmas and New Year.
- **Birthday Retreat**: On top of that, your birthday is your personal holiday - our employees enjoy their birthday with a day off.
- **Food**:We like get-togethers during lunch time. Enjoy tasty, subsidised meals from our FELFEL food fridge.
- **Coffee**: Meet up with your colleagues and grab free coffee.
- **Development**:We support the individual development of our employees.
- **German Lessons**: For our international employees we support German lessons to speed up integration.
- **Creativity**:We offer an innovative and creative environment.
- **People**:We are an international and diverse team with talented and passionate people.
- **Fun**: From time-to-time we organise cool off-site summer and winter team events.



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