Postdoc position: In vivo single-cell CRISPR screening
Vor 5 Tagen
Job description We are looking for a highly motivated and collaborative researcher to join us in advancing these efforts. The candidate will work as part of a multidisciplinary team and be passionate about science, technology, collaboration, and communication. Profile The ideal candidate should have a PhD degree in Biological Engineering, Molecular Biotechnology, Molecular Medicine, (Quantitative) Biology or a related field. The successful candidate will have experience across several of the following areas: cloning, molecular biology techniques and synthetic biology virus production and/or evolution and delivery (AAV, LV) in vivo interrogation of mouse models, including histological techniques, imaging and quantification primary cell isolation, cell culture, and flow cytometry preparation of deep sequencing libraries for functional genomics experiments bioinformatics, statistics, and programming The candidate must have a strong motivation and interest in collaboration with multidisciplinary scientists. They must be able to communicate effectively in a highly interdisciplinary and international environment, which includes a mastery of oral and written English as well as scientific illustration. Workplace Workplace We offer The position is located in the Department of Biosystems Science and Engineering (D-BSSE) of the ETH Zurich in Basel, Switzerland. The D-BSSE is a highly interdisciplinary department – specializing in biological engineering, systems and synthetic biology, bioinformatics and data science, and engineering sciences related to microfluidics and microfabrication. The D-BSSE is centrally located within a biomedical research hub with close links to top academic institutions (e.g., Friedrich Miescher Institute (FMI), Biozentrum and University of Basel) as well as major biotechnology and pharmaceutical companies (e.g., Novartis, Roche, Bayer, and Lonza). The ETH Zurich is a global leader in science and technology and consistently ranks as one of the top universities in the world. Basel, Switzerland is an international city on the border with France and Germany – nested between the Swiss alps and the black forest. The city provides easy access to arts and culture, nature and adventure, and short commutes via train/plain/automobile to anywhere in Europe. chevron_right Working, teaching and research at ETH Zurich We value diversity In line with to find out how we ensure a fair and open environment that allows everyone to grow and flourish. Curious? So are we. We look forward to receiving your application including, as a single PDF: cover letter that mentions your scientific interests and why you are interested in the group CV diplomas and course transcripts contact details of two referees Please submit your applications online. Applications via email will not be considered. Further information can be found on our website. For questions about the position, please contact Prof. Platt () (no applications). Important dates Application submission deadline: 25th July . Zoom interview: 12/13th August (invitations sent by 26th July). In-person interview: 26/27th August (invitations sent by 13th August). Applicant informed of decision: 3rd September . Latest start date: 1st November . Please ensure you are available on the scheduled interview dates and confirm your earliest possible starting date in your application. About ETH Zürich
-
Postdoc in Discovery Sciences
vor 2 Wochen
Basel, Schweiz Novartis Vollzeit393276BR **Postdoc in Discovery Sciences**: Switzerland **About the role** We are seeking an independent and highly motivated researcher to join as a Postdoc Fellow in our dynamic and diverse research team at Novartis. This role presents an exceptional opportunity to engage in the development of translational cellular models and investigate the...
-
Phd Position in Cellular Therapies Against Brain Tumors
vor 5 Stunden
Basel, Schweiz Universität Basel Vollzeit**PhD position in Cellular Therapies against Brain Tumors** **100%, Start in February 2026** **Your position** - Design, develop, and test next-generation armored CAR (Chimeric Antigen Receptor) constructs. - Perform genetic modification of primary human immune cells (T cells and macrophages). - Conduct in vitro validations using advanced models,...
-
Basel, Schweiz Universität Basel VollzeitA position is available in the Brain Tumor Immunotherapy and Biology Lab at the Department of Biomedicine (DBM) in Basel, Switzerland. The successful candidate will work on developing cellular therapies against glioblastoma and brain metastasis. The project focus is on the genetic modification of T cells and macrophages with next-generation armored CARs. Lab...
-
Phd Position On Molecular Mechanisms of Drug
vor 5 Stunden
Basel, Schweiz Universität Basel VollzeitSelected publications of our lab include: 1- PIK3CAH1047R induces multipotency and multi-lineage mammary tumors. Koren S, et al., Nature 2015. 2- Hippo kinases LATS1/2 control human breast cell fate via crosstalk with ERα. Britschgi A, et al., Nature 2017. 3. Glucocorticoids promote breast cancer metastasis. Obradović MMS, et al. Nature 2019. 4. Hepatic...
-
Postdoctoral Researcher in Comparative Single-cell
vor 2 Wochen
Basel, Schweiz Universität Basel Vollzeit**Your position** The goal of this Swiss National Science Foundation (SNSF)-funded project is to investigate the gene regulatory logic of convergent cell fate specification in different parts of the developing vertebrate skeleton, compare it across different vertebrate species and investigate the role of the embryonic tissue environment and the species'...
-
Basel, Basel-Stadt, Schweiz Universität Basel Vollzeit100%, Start in February 2026 A position is available in the Brain Tumor Immunotherapy and Biology Lab at the Department of Biomedicine (DBM) in Basel, Switzerland. The successful candidate will work on developing cellular therapies against glioblastoma and brain metastasis. The project focus is on the genetic modification of T cells and macrophages...
-
Basel, Basel-Stadt, Schweiz Universität Basel VollzeitA position is available in the Brain Tumor Immunotherapy and Biology Lab at the Department of Biomedicine (DBM) in Basel, Switzerland.The successful candidate will work on developing cellular therapies against glioblastoma and brain metastasis. The project focus is on the genetic modification of T cells and macrophages with next-generation armored CARs. Lab...
-
Phd Position in Embryonic Gene Regulation, Tissue
vor 2 Wochen
Basel, Schweiz Universität Basel Vollzeit**Your position** The goal of this Swiss National Science Foundation (SNSF)-funded project is to study the molecular and tissue-scale dynamics during the embryonic formation of the vertebrate skeleton, compare it across different vertebrate species and investigate the role of the embryonic tissue environment and the species' habitats at large. You will be...
-
Basel, Basel-Stadt, Schweiz ETH Zurich VollzeitExperienced Researcher in Development and application of computational methods for functional genomics100%, Basel, fixed-termThe Laboratory for Biological Engineering (Prof. Randall J Platt) of the ETH Zurich in Basel, Switzerland develops genome engineering technologies and applies them to a range of fundamental and disease-focused areas. To advance these...
-
Basel, Schweiz Bio Engineering Laboratory & Novartis VollzeitJob description The postdoc will develop new cell-culture platforms and tisssue models intended to mimic the kidney microenvironment. He will use these platforms to culture stem-cell-derived renal cells to realize a renal tubular unit. The postdoc will then focus on the functional characterization of the tubular unit to confirm that the developed model...
