Global Science Lead Enzyme Therapeutics

vor 1 Tag

Lausanne, Schweiz Nestle Vollzeit

**Position Snapshot**:
Location: Vers-chez-les-Blancs, Switzerland
Company: Nestlé Health Science
Permanent contract, Full time
Average travel expectations: 20%/year approx.

This is a permanent opportunity and here at Nestlé many of our colleagues work flexibly and in many different ways, different core hours and remote working. Please talk to us during the recruitment process about what flexibility could look like for you.

This position can also be based in UK or US

**Position summary**:
Reporting to the Global Head of Strategic Research Collaborations, you will be responsible for research and preclinical/non-clinical studies conducted on behalf of NHSc with external partners and/or Contract Research Organizations (CROs).

**A day in the life of a Global Science Lead Allergy Therapeutics**:

- Design and oversee IND- and CTA- enabling preclinical programs: including target identification and validation, relevant disease models for preclinical proof-of concept, PK/PD and dose range finding studies, safety, and drug non-clinical developments, such as CMC to proceed to IND and enable phase 1 human studies
- Initiate advance key development programs, including preclinical study planning and budgeting, execution oversight and reporting to steering committee(s)
- Secure the differentiation of early & mid stage compounds including identification of new indications and successful generation of new IP
- Target identification and engagement markers
- Design proof of concept studies in relevant animal disease models
- Conduct scientific and technical review for nonclinical studies performed with external collaborators or CROs.
- Review and finalize nonclinical study reports (both non-GLP and GLP studies).
- Together pharmacology/toxicology and regulatory project lead engage with regulatory agencies to resolve nonclinical issues
- Implementation of scientific discoveries, breakthrough technology platforms, as well as early to mid-terms target assets in the allergy and immune-related gastro-intestinal (GI) therapeutics (aligned with NHSc Rx strategy and product portfolio)"
- Act as Preclinical Development representative on project teams and/or sub teams for clinical development of novel allergy/immunology therapeutics (Rx)

***What will make you successful**:

- Ph.D. or MD/Ph.D in Biochemistry or Pharmacology with specialization in Protein chemistry/Enzymology (enzyme expert)
- Experience in drug discovery and PK/PD assessment and modeling.
- Early drug development experience, with minimum 5 to 8 years working in biotech/pharma companies
- Experience in coordination, organization, analysis, and documentation of nonclinical studies
- Experience in gastro-intestinal and metabolism related diseases where dysfunctional enzymes play a key role in driving pathology
- Experience managing research programs involving external partners.
- Exposure to business development / acquisition a plus

Nestlé Health Science is a leader in the science of nutrition, offering an extensive portfolio of science-based consumer health, medical nutrition, pharmaceutical therapies, and vitamin and supplement brands. Headquartered in Switzerland, we have more than 11,000 employees around the world, with products available in more than 140 countries.

Aimmune Therapeutics is the pharmaceutical unit of Nestle Health Science (NHSc), with a focus on the advancement of treatments for food allergy, GI disorders, and other food-mediated diseases. We are continuing to build a world-class R&D organization with a strong development infrastructure to support programs in gastroenterology, food allergies and other metabolic & inflammatory diseases. The R&D function within Aimmune Therapeutics drives development activities related to the pharmaceutical pipeline.

  • Global Alliance Director

    vor 4 Monaten

    Lausanne, Schweiz HAYA Therapeutics SA Vollzeit

    Location: - This position will be at Haya Therapeutics' headquarters in Lausanne, Switzerland, or San Diego, CA. - Requests a full time presence on-site**Conditions of Employment**: Proof of Eligibility to work in Switzerland (Swiss work permit or Swiss / European citizenship) or United States of America (U.S. citizenship or work permit/authorization). The...

  • Global Customer Relationship Manager

    vor 1 Woche

    Lausanne, Schweiz Nestlé Health Science Vollzeit

    Position Snapshot Location: Flexible. Europe-preferred Company: Société des Produits Nestlé S.A. Act. Rate: Full-Time Act. Rate 100% Type of contact: Permanent contract Genuine opportunities for career and personal development Modern “smart office” locations providing agile & collaborative workspaces Dynamic international working...

  • Global Clinical Development Lead

    vor 7 Monaten

    Lausanne, Schweiz Nestle Operational Services Worldwide SA Vollzeit

    **Position Snapshot** Location: Nestlé Health Science Lausanne, Switzerland Company: Nestlé Health Science Act. Rate: Full-Time Act. Rate 100% Type of contract: Permanent contract **What we offer at Nestlé** Flexible work policies in terms of core hours and working from home. Please talk to us during the recruitment process about what flexibility could...

  • Global Market Access

    vor 7 Monaten

    Lausanne, Schweiz Nestle Operational Services Worldwide SA Vollzeit

    **Position Snapshot** Location: Nestlé Health Science Lausanne, Switzerland Company: Nestlé Health Science Act. Rate: Full-Time Type of contract: Permanent contract **What we offer at Nestlé** Flexible work policies in terms of core hours and working from home. Please talk to us during the recruitment process about what flexibility could look like for...

  • Global Data

    vor 1 Tag

    Lausanne, Schweiz Nestle Vollzeit

    **Position Snapshot** Location: Lausanne, Switzerland Company: Nestlé Health Science Act. Rate: Full Time Act. Rate 100% Type of contact: Permanent contract **What we offer at Nestlé** Flexible work policies in terms of core hours and working from home. Please talk to us during the recruitment process about what flexibility could look like for...

  • Vice President of Business Development

    vor 4 Monaten

    Lausanne, Schweiz HAYA Therapeutics SA Vollzeit

    Location: - This position will be at Haya Therapeutics' headquarters in Lausanne, Switzerland, or San Diego, CA. - Requests a full time presence on-site**Conditions of Employment**: Proof of Eligibility to work in Switzerland (Swiss work permit or Swiss / European citizenship) or United States of America (U.S. citizenship or work permit/authorization). The...

  • Global R&d Drug Project Leader

    vor 1 Woche

    Lausanne, Schweiz Nestle Vollzeit

    Nestlé Health Science is a globally recognized leader in the science of nutrition, with more than 11,000 employees around the world. With a portfolio of science-based consumer health, medical nutrition, vitamin and supplement brands, and pharmaceutical therapies, we are redefining the management of health. **Position Snapshot**: Location:...

  • Global Ecodesign

    vor 2 Wochen

    Lausanne, Schweiz Quantis Vollzeit

    **WHY YOU’LL LOVE QUANTIS** Quantis is a leading sustainability consultancy pioneering approaches to solve critical environmental challenges. For nearly two decades, our dynamic and visionary team has partnered with organizations across the globe to transform their industries and pave the way for a planetary economy that aligns business with nature. We...

  • Global Land

    vor 1 Woche

    Lausanne, Schweiz Quantis Vollzeit

    **WHY YOU’LL LOVE QUANTIS** Quantis is a leading sustainability consultancy pioneering approaches to solve critical environmental challenges. For nearly two decades, our dynamic and visionary team has partnered with organizations across the globe to transform their industries and pave the way for a planetary economy that aligns business with nature. We...

  • Global Medical Affairs Lead Metabolic Health

    Vor 4 Tagen

    Lausanne, Schweiz Nestle Vollzeit

    Nestlé Health Science was created in 2011 by Nestlé, the leading food and beverage company. We are a unique health science company focused on advancing the role nutrition plays in changing the course of health for consumers, patients and healthcare professionals. Focused on delivering quality-of-life benefits through nutritional solutions, we harness...

  • Global Stakeholder Engagement

    vor 2 Wochen

    Lausanne, Schweiz Quantis Vollzeit

    **WHY YOU’LL LOVE QUANTIS** Quantis is a leading sustainability consultancy pioneering approaches to solve critical environmental challenges. For nearly two decades, our dynamic and visionary team has partnered with organizations across the globe to transform their industries and pave the way for a planetary economy that aligns business with nature. We...

  • Global Marketing Lead/Director, Solgar

    vor 3 Wochen

    Lausanne, Schweiz Nestlé SA Vollzeit

    Location: Nestlé Health Science Barcelona & Europe (preferred) or US based (flexible)Company: Nestlé Health ScienceAct. Rate: Full-Time Act. Rate 100%Type of contract: Permanent contractWhat we offer at NestléFlexible combination of office-based and remote work. Please talk to us during the recruitment process about what flexibility could look like for...

  • Global Footprint

    vor 2 Wochen

    Lausanne, Schweiz Quantis Vollzeit

    **WHY YOU’LL LOVE QUANTIS** Quantis is a leading sustainability consultancy pioneering approaches to solve critical environmental challenges. For nearly two decades, our dynamic and visionary team has partnered with organizations across the globe to transform their industries and pave the way for a planetary economy that aligns business with nature. We...

  • Global Nature

    vor 7 Monaten

    Lausanne, Schweiz Quantis Vollzeit

    Quantis constantly strives to nurture and maintain the best expertise and quality of delivery. Consistent excellence in our work supports efficient delivery and client transformation. The Global Nature-Water Lead will ensure Quantis’ excellence in the field of Nature-Water and support our clients’ transformation towards sustainability. Working across...

  • Global Program Lead, Global Regulatory Affairs

    Vor 7 Tagen

    Lausanne, Schweiz Debiopharm Vollzeit

    Description Debiopharm is an independent biopharmaceutical company based in Switzerland with an ongoing commitment to research in oncology and bacterial infections in order to improving patient outcomes and quality of life. Our main activities include drug development, drug manufacturing and digital health investment. Debiopharm International SA aims to...

  • Global Strategic Insights, Goals

    vor 2 Wochen

    Lausanne, Schweiz Quantis Vollzeit

    **WHY YOU’LL LOVE QUANTIS** Quantis is a leading sustainability consultancy pioneering approaches to solve critical environmental challenges. For nearly two decades, our dynamic and visionary team has partnered with organizations across the globe to transform their industries and pave the way for a planetary economy that aligns business with nature. We...

  • Global Supply Chain Management

    vor 2 Wochen

    Lausanne, Schweiz Quantis Vollzeit

    **WHY YOU’LL LOVE QUANTIS** Quantis is a leading sustainability consultancy pioneering approaches to solve critical environmental challenges. For nearly two decades, our dynamic and visionary team has partnered with organizations across the globe to transform their industries and pave the way for a planetary economy that aligns business with nature. We...

  • Global New Operating Models

    vor 2 Wochen

    Lausanne, Schweiz Quantis Vollzeit

    **WHY YOU’LL LOVE QUANTIS** Quantis is a leading sustainability consultancy pioneering approaches to solve critical environmental challenges. For nearly two decades, our dynamic and visionary team has partnered with organizations across the globe to transform their industries and pave the way for a planetary economy that aligns business with nature. We...

  • Senior Software Engineer – Life Science

    vor 5 Monaten

    Lausanne, Schweiz Danaher - Global Vollzeit

    For over 170 years,Leica Microsystems has helped shape the future by developing groundbreaking optical and digital solutions. As a global leader, we’re driven by continuous improvement to excite our customers and to create the best work environment for our people. Customer focus, innovation, and teamwork are at the core of our culture and the foundation of...

  • Global Labelling Process Coordinator

    vor 2 Wochen

    Lausanne, Schweiz Nestle Vollzeit

    Nestlé Health Science is a globally recognized leader in the science of nutrition, with more than 11,000 employees around the world. With a portfolio of science-based consumer health, medical nutrition, vitamin and supplement brands, and pharmaceutical therapies, we are redefining the management of health **Position Snapshot**: Position Snapshot Location:...