Head of Toxicology

Vor 6 Tagen

Lausanne, Schweiz Galderma Vollzeit

With a unique legacy in dermatology as well as decades of cutting-edge innovation, Galderma is the leading company solely dedicated to skin and advancing the future of dermatology.

We look for people who focus on getting results, embrace learning and bring a positive energy. They must combine initiative with a sense of teamwork and collaboration. Above all, they must be passionate about doing something meaningful for consumers, patients and the healthcare professionals we serve every day. We aim to empower each employee and to promote their personal growth all the while ensuring business needs are met now and into the future. Across our company, we embrace diversity and respect the dignity, privacy and personal rights of every employee.

At Galderma, we actively give our teams reasons to believe in our ambition to become the leading dermatology company in the world. With us, you have the ultimate opportunity to gain new and challenging work experiences and create unparalleled, direct impact.

In an innovative and dynamic environment, you will be responsible for the strategy, conduct and interpretation of the global toxicology activities, required for the evaluation, selection and development of future systemic (oral and biological) and topical drug.

Location: Lausanne or Zug

**Responsibilities**
- Participates in the implementation of the Research and Early Development Strategy and implements the corresponding technological solutions
- Proposes the strategy in Toxicology in line with the global strategy of Global R&D and implements the corresponding technological solutions
- Contributes to the evaluation and prioritization of projects of the Global R&D portfolio
- Is a member of Research and Development project teams and interacts with external health authorities
- Defines the needs, selects and maintains a pool of CRO partners to conduct the toxicology activities needed to implement the R&D strategy
- Organizes and directs the safety evaluation activities (profiling, safety profile, therapeutic margin) necessary for the entry into human clinical evaluation of systemic and topical projects, including participation in Project Teams and interaction with Health Authorities
- Organizes and directs the toxicology evaluation activities in the Development phases necessary to guarantee a portfolio of innovative projects aligned with the strategy of global R&D. Participates in Project Teams and interacts with Health Authorities
- Contributes to Target Identification / Target Validation activities to maintain an innovative and competitive portfolio of Research projects
- Ensures the identification, selection and management of strategic collaborations of the Research and Early Development Department
- Provides scouting, evaluation, and recommends opportunities for licensing and / or internalization of molecules and / or projects in the different phases of Research and Development
- Contributes to the management of the global Research and Early Development budget

**Requirements**:

- PhD degree in life sciences plus registered as a Toxicologist (ERT or DABT)
- Training in the field of biotechnology in general and biological drugs in particular
- Training on Regulatory Aspects of Clinical Drug Evaluation
- Minimum 15 years of expertise in academic and industrial research in the field of pharmacology and toxicology associated with human health research, of which at least 5 years must be from working in the pharma/biotech industry
- Strong experience in regulatory toxicology, GLP regulations and ICH guidelines, including preparation of nonclinical CTD modules
- Experience with both small molecules and biologicals is a plus
- Strong project leadership skills required to own the safety assessment contribution to the portfolio of global safety projects
- Demonstrated experience in conducting collaborative research programs with external partners
- Excellent teaching and presentation skills, as well as an excellent leadership capacity with a multicultural and multidisciplinary team
- International recognition for your work (conferences, publications, patents)
- Fluent English

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