Roche Postdoctoral Fellow in DNA Damage Response and Synthetic Lethality

vor 3 Wochen


Basel, Schweiz Roche Vollzeit

The Position

As a Postdoctoral Fellow in the Department of Cancer Cell Targeted Therapies (CCTT), you will focus on exploratory research projects on genome stability and DNA repair. We are looking for a highly motivated candidate to join our cross-functional team in order to strengthen and advance our efforts in the area of DNA Damage Response (DDR) and Synthetic Lethality for the treatment of various cancer types. 

In this position, you will:

Perform cutting edge science using molecular and cell biology assays, including fluorescence microscopy and CRISPR technologies. 

Design and execute experiments and perform data analysis.

Communicate scientific progress through internal meetings and publications.

You are a curious, science-driven and highly motivated researcher with the aspiration to influence your professional development and to be part of a dynamic and growing organization where you can continuously learn and innovate. 

You have very good interpersonal and communication skills, are able to build good working relationships, and are an outstanding teammate. Your experience and investigative attitude allow you to work independently, to design, perform, and interpret experiments, and to embark on new scientific methodologies.

You hold a PhD degree in a relevant field, and you graduated from your PhD programme no more than two years ago.

You also have experience and expertise in the following:

Extensive experience with DNA repair-related assays.

Strong background in vector design, genetic engineering, and molecular biology techniques.

Strong hands-on experience with a wide range of cellular and molecular biology techniques and cellular assays including cell culture, flow cytometry, fluorescence microscopy and CRISPR-mediated genome editing.

Ideally, you also have the following experience:

Experience in performing genetic screens

Basic programming skills Python, R)

This position is sponsored by the Roche Postdoctoral Fellowship (RPF) Programme. 

The RPF Programme has the ambition to build and maintain the Scientific Leadership of the future and to provide leading Roche scientists with the opportunity to collaborate with talented postdoctoral researchers, and leading academic research groups, from around the world. One of the key aims is to advance basic science and technologies that will be published in top-rated, peer-reviewed scientific journals, if necessary preceded by priority patent applications.

The duration of RPF project is initially set for two years , with the possibility of extension for a third year. You will be based at the Roche Innovation Center in Basel, Switzerland

When does it start?
The start date of this fellowship is based on availability. Please clearly indicate your preferred starting date on your motivation letter. All applications always need to include a CV, motivation letter, and a publication list.



  • Basel, Schweiz Roche Vollzeit

    The Position Due to internal progression, our Synthetic Molecules Technical Development department has an opportunity for a Section Head of Process Chemistry & Catalysis. As the Section Head Process Chemistry, you will be working in the department “Process Chemistry & Catalysis” within the department "Synthetic Molecules Technical Development”. ...


  • Basel, Schweiz Roche Vollzeit

    The Position In Roche´s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility...


  • Basel, Schweiz Roche Vollzeit

    The Position Accounting and External Reporting Specialist (80% - 100%) Job description We offer an exciting opportunity to an experienced and qualified finance professional who would like to gain more insights to Roche Group’s financial operations. You will be an integral member of the Group Accounting and External Reporting team at Roche’s...


  • Basel, Schweiz Universität Basel Vollzeit

    **Stereoselective catalysis** Ph.D. position in synthetic chemistry at the University of Basel, Department of Chemistry in catalyst and reaction development. We just published the first method for the stereoselective synthesis of ammonium ions with stereogenic nitrogen centers under catalyst control (doi.org/10.1021/acs.orglett.3c00195). We want to extend...


  • Basel, Schweiz Roche Vollzeit

    The Position In Roche’s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility...


  • Basel, Schweiz LifeMine Vollzeit

    Headquartered in Cambridge, Massachusetts, USA, LifeMine is opening its European Headquarters in Basel. Our 4,000 m2 facility is in Klybeck, Basel, right next to the beautiful Rhine River and the train station, also close to City Center. The Klybeck area is home to many top US and Swiss pharmaceutical and Biotech companies in Europe's biotechnology...


  • Basel, Schweiz Universität Basel Vollzeit

    The Center for Economic Psychology at the Faculty of Psychology of the University of Basel is searching for a postdoctoral researcher. The Center for Economic Psychology is directed by Prof. Dr. Jörg Rieskamp and is part of the growing Faculty of Psychology at the University of Basel, one of the leading research universities in Europe. **Your...


  • Basel, Schweiz Roche Vollzeit

    The Position In Roche’sPharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world’s toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicines. Together, we create a culture defined by curiosity, responsibility...


  • Basel, Schweiz Roche Vollzeit

    The Position In this role, you will be working in “Synthetic Molecules Technical Development” (PTDC). PTDC brings a broad range of experience across drug substance (DS), drug product (DP), analytical sciences as well as manufacturing science & technology, and collaborates closely with key partners in Research and Early Development as well as with...

  • Research Scientist

    Vor 3 Tagen


    Basel, Schweiz Novartis Vollzeit

    394946BR **Research Scientist (6mth contract) - Synthetic Organic/MedChem**: Switzerland **About the role** Novartis is an innovative medicines company. Every day, we work to reimagine medicine to improve and extend people’s lives so that patients, healthcare professionals and societies are empowered in the face of serious disease. Our medicines reach...


  • Basel, Schweiz Roche Vollzeit

    The Position Diagnostics Strategic Finance Champion Location: Basel; Switzerland Reporting to the Head of Dia (Diagnostics) Strategic Finance, the Strategic Finance Champion leads a team of strategic finance partners supporting senior stakeholders across our Roche Diagnostics Division (including Strategy and Partnering Office organization), and...


  • Basel, Basel-Stadt, Schweiz Roche Diagnostics International AG Vollzeit

    Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people's varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche,...


  • Basel, Basel-City, Schweiz Roche Diagnostics International AG Vollzeit

    Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people’s varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche,...

  • Research Associate

    vor 3 Wochen


    Basel, Schweiz Roche Vollzeit

    The Position At Roche Pharmaceutical Research and Early Development Organization (pRED), we believe that rapid advances in science and technology are our greatest opportunity to rethink the way we address some of the world’s most challenging unmet health needs and have an even more profound impact on patients and society.  We are looking for a...


  • Basel, Basel-Stadt, Schweiz F. Hoffmann-La Roche AG Vollzeit

    Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people's varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche,...


  • Basel, Basel-Stadt, Schweiz F. Hoffmann-La Roche AG Vollzeit

    Roche fosters diversity, equity and inclusion, representing the communities we serve. When dealing with healthcare on a global scale, diversity is an essential ingredient to success. We believe that inclusion is key to understanding people's varied healthcare needs. Together, we embrace individuality and share a passion for exceptional care. Join Roche,...

  • Associate Director

    Vor 7 Tagen


    Basel, Schweiz Skyhawk Therapeutics Europe GmbH Vollzeit

    Tasks - Act as a leading scientist on one or more discovery research projects with the ability to drive conclusive results - Leverage expertise in synthetic organic and medicinal chemistry to drive SAR optimization cycle to further pipeline goals. - Effectively manage work conducted at global CROs - Participation in scientific review and assessment of...


  • Basel, Schweiz Roche Vollzeit

    The Position Position Summary: This is a unique position, designed to drive ongoing development and performance in the P&OG Consulting AoP, specifically in the Change space. The Consulting Content Lead has the following responsibilities: Establish consistent best practices in the area of Change and the supporting infrastructure, tools,...


  • Basel, Schweiz Roche Vollzeit

    The Position Digital health technology is transforming the way we develop personalized medicines for patients. Roche is dedicated to creating community- and regulator-accepted digital endpoints and digital outcomes that redefine the way we measure disease progression in clinical drug trials, and make them accessible to Biopharma companies and the...


  • Basel, Schweiz Implementation Science in Health Care Vollzeit

    Implementation Science in Health Care_ **Postdoctoral Researcher in Biomedical Artificial Intelligence** **80-100 % **:The position is part of the StrOntEx project, an SNF- and DFG-funded collaboration between the Medical Knowledge and Decision Support group at the Institute for Implementation Science in Health Care of the Faculty of Medicine at the...