Chief Development Chemist for Synthetics
Vor 5 Tagen
Company Overview
Roches' Synthetic Molecules Technical Development department drives innovation and efficiency in the development of synthetic molecules.
We are seeking a highly experienced Chief Development Chemist to lead our Process Chemistry Section and contribute to the advancement of our synthetic molecule pipeline.
Job Summary
The Chief Development Chemist will oversee a team of scientists and associates responsible for end-to-end process chemistry, from design to commercial manufacturing processes. Key responsibilities include:
- Leading a Process Chemistry Section with approx. 15 co-workers according to Roche Leadership Commitments.
- Supporting and delivering a portfolio of projects with focus on oligonucleotides and peptides by assigning resources, setting priorities, and providing sound judgment for decision making and problem solving.
- Fostering the development of cost-efficient and robust processes and process understanding by using state-of-the-art science and methodologies to enable lean manufacturing.
- Providing scientific and technical input to project teams and further developing your section towards a lean and agile organization.
- Supporting Roche's regulatory submissions by applying principles of Quality by Design to drug substance development and corresponding documentation while ensuring compliance with quality and regulatory requirements.
- Actively supporting the departmental digitalization and M&S efforts as well as contributing to defining the department's future technical and regulatory strategies and concepts.
About You
We are looking for a highly experienced candidate with a PhD degree in organic chemistry and at least 10 years of experience in process chemistry for synthetic molecules, spanning the entire range from route design, process development, process characterization, and process transfer to commercial manufacturing.
A strong ability to act visionary and be the catalyst, mentor, and architect for teams and members is essential. Profound experience as a matrix leader of complex projects is required. Additionally, excellent knowledge in oligonucleotide and peptide chemistry, extensive experience in working with external collaboration partners in Europe, US, and Asia, and comprehensive understanding of sustainable process development are necessary.
The estimated annual salary for this role is between $180,000 - $220,000 based on industry standards and location.
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