Project Toxicologist with large molecule experience

At Roche you can show up as yourself, embraced for the unique qualities you bring. Our culture encourages personal expression, open dialogue, and genuine connections, where you are valued, accepted and respected for who you are, allowing you to thrive both personally and professionally. This is how we aim to prevent, stop and cure diseases and ensure everyone has access to healthcare today and for generations to come. Join Roche, where every voice matters.The PositionIn Roche ́s Pharmaceutical Research and Early Development organisation (pRED), we make transformative medicines for patients in order to tackle some of the world's toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicine. Together, we create a culture defined by curiosity, responsibility and humility, where our talented people are empowered and inspired to bring forward extraordinary life-changing innovation at speed.pRED's Pharmaceutical Sciences (PS) group enables discovery and development of safe and effective therapeutics at optimal doses in relevant populations with a vision to power translation, continuously improve the accuracy of our predictions and accelerate the development of tomorrow's medicines. PS supports discovery and development across the whole value chain from target assessment to on-market and beyond.The position is within the Translational Safety Assessment Chapter in Pharmaceutical Sciences. We drive the non-clinical safety assessment of drug candidates from small molecules to complex biological products through all the discovery and development phases at Roche.The OpportunityWe are offering an outstanding opportunity for a Project Toxicologist to work with multidisciplinary teams in preclinical drug discovery and development with a focus on mechanistic, translational and regulatory aspects.Your main responsibilities in this position are:The development and execution of an integrated and scientifically sound nonclinical safety strategy from target assessment through clinical trial conduct to registrationRepresenting Pharmaceutical Sciences in Global project teams and acting as a key contributor to the selection and timely development of potential new medicines through close interactions with discovery therapeutic areas, and affiliated non-clinical, clinical development and regulatory functionsSteering non-clinical safety evaluations for potential in-licensing opportunities, as well as representing non-clinical safety on collaborations with external partnersGenerating concise safety assessments for internal decision-making, as well as regulatory submission documentation to facilitate health authority reviews and approval processes in all phases of pre-clinical and clinical drug developmentLead a team of experts at critical stages of the project; with your excellent interpersonal skills, your leadership capabilities and your collaborative attitude, you successfully master problems in a highly matrixed environmentWho you areYou have a PhD, DVM or equivalent with a minimum of 10 years of experience in large molecule development with a proven track record of interacting with global health authorities.You can manage scientific issues, providing strategic development direction, with a demonstrated ability to manage multiple projects across various development stages. Board certification, such as a DABT, is an advantage.You can effectively communicate to key stakeholders at the appropriate level of detail in representing the key nonclinical concerns.You are experienced working within a matrixed team environment as both a member and a leader with strong organizational and interpersonal skills.You can influence through effective and constructive communication, respectful challenge, and persuasion across the entire research and development organization.You are passionate about mentoring junior colleagues and sharing knowledge.Unwavering focus, collaborative teamwork and exceptional delivery are key behaviours that drive our mission of doing now what patients need next. Together, we can be transformative.If you are passionate about contributing to a committed team and have the dedication to partnership and innovation, Roche is the place for you Every role at Roche plays a part in making a difference in patients' lives.Apply now and join us in making an impactLocationBasel, Switzerland and Welwyn, UKWho we areA healthier future drives us to innovate. Together, more than 100'000 employees across the globe are dedicated to advance science, ensuring everyone has access to healthcare today and for generations to come. Our efforts result in more than 26 million people treated with our medicines and over 30 billion tests conducted using our Diagnostics products. We empower each other to explore new possibilities, foster creativity, and keep our ambitions high, so we can deliver life-changing healthcare solutions that make a global impact.Let's build a healthier future, together.Roche is an Equal Opportunity Employer.