Snr Principal Scientist Translational
vor 1 Woche
**About the Role**: Location: Basel, Switzerland Full time, onsite, #LI-Onsite The Immunology Department (IMM-DA) at Novartis has a strong track record in discovery and development of novel therapies for the treatment of autoimmune and inflammatory diseases. We are looking for an experienced Immunologist for our Translational Research (TR) group. The TR group is an integrated group of scientists with strong expertise in in vivo Pharmacology, Molecular Pathology, disease-relevant in vitro models, and Data Science. The TR group conducts preclinical experiments and uses patient data and human biosamples to support the compound portfolio of IMM-DA end-to-end. **Responsibilities**: - Generate preclinical in vivo and translational data in support of key portfolio projects. - Address key translational research questions for novel drugs related to mechanisms of action, asset differentiation, in vivo PK/PD relationship and exploratory biomarkers from animal studies and/or patient samples. - Represent TR on program discovery and development teams. Lead a target discovery effort or drug discovery project from a translational perspective. Contribute to the overall department’s strategic direction with special focus on increasing the impact of translational research approaches in drug discovery and development. - Lead internal and external collaborations to increase team capabilities or address a strategic need. - Take initiative to identify, pilot and internalize emerging technical approaches that may drive increased value for portfolio execution. - Prepare and/or direct the preparation and review of Preclinical Pharmacology sections of IBs, INDs, abstracts, and manuscripts. **Diversity & Inclusion / EEO**: - We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve._ **Role Requirements**: What you will bring to the role: - Ph.D. or MD/PhD with PostDoc in Immunology, Pharmacology, or related discipline plus >5 years of professional experience in academia or industry. - Expert understanding of in vivo disease models and experience in performing mechanistic studies in rodent models of autoimmune and inflammatory diseases is required. - Immunology/autoimmune disease knowledge, including target and mechanism knowledge (e.g. SLE, arthritis, atopic dermatitis) and awareness of clinical standard of care. - Understanding of fundamentals and practice of the drug discovery process in pharma industry is of advantage. - Excellent written and oral communication skills. - Self-motivated and collaborative, with excellent time management and interpersonal skills. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our communities we serve. Accessibility and accommodation Division Biomedical Research Business Unit IMMUNOLOGY - NIBR Location Switzerland Site Basel Company / Legal Entity Novartis Pharma AG Functional Area Research & Development Job Type Full Time Employment Type Regular Shift Work No Access Job Account
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