Snr Principal Scientist Translational

vor 1 Woche

Basel, Schweiz Novartis Vollzeit

**About the Role**: Location: Basel, Switzerland Full time, onsite, #LI-Onsite The Immunology Department (IMM-DA) at Novartis has a strong track record in discovery and development of novel therapies for the treatment of autoimmune and inflammatory diseases. We are looking for an experienced Immunologist for our Translational Research (TR) group. The TR group is an integrated group of scientists with strong expertise in in vivo Pharmacology, Molecular Pathology, disease-relevant in vitro models, and Data Science. The TR group conducts preclinical experiments and uses patient data and human biosamples to support the compound portfolio of IMM-DA end-to-end. **Responsibilities**: - Generate preclinical in vivo and translational data in support of key portfolio projects. - Address key translational research questions for novel drugs related to mechanisms of action, asset differentiation, in vivo PK/PD relationship and exploratory biomarkers from animal studies and/or patient samples. - Represent TR on program discovery and development teams. Lead a target discovery effort or drug discovery project from a translational perspective. Contribute to the overall department’s strategic direction with special focus on increasing the impact of translational research approaches in drug discovery and development. - Lead internal and external collaborations to increase team capabilities or address a strategic need. - Take initiative to identify, pilot and internalize emerging technical approaches that may drive increased value for portfolio execution. - Prepare and/or direct the preparation and review of Preclinical Pharmacology sections of IBs, INDs, abstracts, and manuscripts. **Diversity & Inclusion / EEO**: - We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve._ **Role Requirements**: What you will bring to the role: - Ph.D. or MD/PhD with PostDoc in Immunology, Pharmacology, or related discipline plus >5 years of professional experience in academia or industry. - Expert understanding of in vivo disease models and experience in performing mechanistic studies in rodent models of autoimmune and inflammatory diseases is required. - Immunology/autoimmune disease knowledge, including target and mechanism knowledge (e.g. SLE, arthritis, atopic dermatitis) and awareness of clinical standard of care. - Understanding of fundamentals and practice of the drug discovery process in pharma industry is of advantage. - Excellent written and oral communication skills. - Self-motivated and collaborative, with excellent time management and interpersonal skills. Why Novartis: Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our communities we serve. Accessibility and accommodation Division Biomedical Research Business Unit IMMUNOLOGY - NIBR Location Switzerland Site Basel Company / Legal Entity Novartis Pharma AG Functional Area Research & Development Job Type Full Time Employment Type Regular Shift Work No Access Job Account

  • Principal Scientist

    vor 1 Woche

    Basel, Schweiz Novartis Vollzeit

    384688BR **Principal Scientist - Drug Discovery Immunology (80-100%*)**: Switzerland **About the role** The Immunology Research Disease Area at Novartis Biomedical Research is investing in the discovery of novel and transformative therapies to improve the life of affected patients. To help deliver on this team effort, Immunology Research is seeking an...

  • Medical Director

    vor 1 Woche

    Basel, Schweiz Novartis Vollzeit

    **About the Role**: 350 million! That is the estimated number of patients worldwide suffering of atopic dermatitis or psoriasis. Join Novartis to help find the right drugs to transform and improve patient's lives all around the world. You will provide medical and scientific leadership and expertise in a role that significantly impacts the entire Novartis...

  • Scientist I/ii, Biomarkers

    vor 2 Wochen

    Basel, Schweiz Monte Rosa Therapeutics, Inc Vollzeit

    Overview: Monte Rosa Therapeutics is looking for an experienced, energetic, and self-motivated Scientist to join our Biomarker team in Basel. This Scientist will conduct well-designed and reliably executed experiments in the lab as well as monitoring of outsourced activities that are aimed at assessing preclinical, translational and clinical samples. The...

  • Data Scientist

    vor 2 Wochen

    Basel, Schweiz Universität Basel Vollzeit

    University Digestive Health Care Center - Clarunis, Basel, Switzerland is the joint competence centre of Claraspital and Basel University Hospital for all patients in need of abdominal treatment. Clarunis combines the specialist knowledge, research activities and number of patients treated of both hospitals to further increase and enhance the quality of...

  • Principal Scientist Formulation Development

    vor 2 Wochen

    Basel, Schweiz Coopers Group AG Vollzeit

    Principal Scientist Formulation Development Our international client in Basel is looking for a professional for a position with following **responsibilities**: - Support of drug product formulation development services for parenteral products - Design and execute formulation studies. - Plan and perform characterization studies for liquid and lyophilized...

  • Senior/ Principal Scientist

    Vor 6 Tagen

    Basel, Basel-Stadt, Schweiz Roche Vollzeit

    Bei Roche kannst du ganz du selbst sein und wirst für deine einzigartigen Qualitäten geschätzt. Unsere Kultur fördert persönlichen Ausdruck, offenen Dialog und echte Verbindungen. Hier wirst du für das, was du bist, wertgeschätzt, akzeptiert und respektiert. Dies schafft ein Umfeld, in dem du sowohl persönlich als auch beruflich wachsen kannst....

  • Research Associate, Cell Therapy Translational Research

    vor 1 Woche

    Basel, Schweiz myScience Vollzeit

    Research Associate, Cell Therapy Translational Research (100%) University of Basel Workplace Basel - North West Switzerland - Switzerland Category Health | Life Sciences Position Senior Scientist / Postdoc Published 20 January 2026 Research Associate, Cell Therapy Translational Research (100%) Ref.: IOB165 The Institute of Molecular and Clinical...

  • Translational Data Scientist

    vor 2 Wochen

    Basel, Schweiz Universität Basel Vollzeit

    The Swiss Tropical and Public Health Institute (Swiss TPH) is a world-leading institute in global health with a particular focus on low - and middle-income countries. Associated with the University of Basel, Swiss TPH combines research, education and services at local, national and international levels. 950 people from 95 nations work at Swiss TPH focusing...

  • In Vitro Adme Scientist

    vor 2 Wochen

    Basel, Schweiz Novartis Vollzeit

    As an ADME Scientist with NIBR's Pharmacokinetic Sciences (PKS) organization, you will facilitate the ADME optimization of small molecules across discovery phases. The characterization of the absorption, distribution, metabolism, and excretion (ADME) properties using in vitro assays such as metabolic stability and cellular permeability provides critical...

  • Lead Principal Data Scientist, R&d

    vor 2 Wochen

    Basel, Schweiz Lonza Vollzeit

    **Switzerland, Basel** **Location. Basel, Switzerland.** Today, Lonza is a global leader in life sciences operating across five continents. While we work in science, there’s no magic formula to how we do it. Our greatest scientific solution is talented people working together, devising ideas that help businesses to help people. In exchange, we let our...