Principal Scientist I

6000 This is the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on new technologies that have the potential to help produce therapeutic breakthroughs for patients. The Biotherapeutic Engineering and Gene Therapy (BEGT) group is a part of the NIBR Biologics Center (NBC). BEGT drives a diverse portfolio of modalities including therapeutic proteins, multi-specific antibodies, CAR-T, RNA therapeutics, AAV and lentiviral vectors.
- As a Principal Scientist, you will further strengthen our protein engineering team in Basel by bringing expertise in protein-based therapeutics. You will join a dynamic team working closely with Disease Areas to establish new strategies made possible by the design of next generation biotherapeutics.
- Your responsibilities include, but are not limited to:
- Protein engineering in general with focus on bi-/multispecific formats.
- Enhance our protein engineering platform and develop novel technologies to expand our discovery of bi-/multispecific biotherapeutics.
- Collaborate with Disease Areas to solve therapeutic challenges by design of the next generation of recombinant biotherapeutics.
- Collaborate within other units inside NBC to profile functional and biophysical properties of designed molecules.
- Present experimental designs, protocols, results and interpretations to a varied audience
- Maintain familiarity with current scientific literature and techniques in the field of bi/multi-specific formats.
- Demonstrate good organizational and communication skills. Expected to be accountable for effectiveness and timelines of completion of project goals.
- Ability to balance multiple projects under a demanding timeline.

**Commitment to Diversity & Inclusion**:

- Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve._

**Minimum requirements**
- Ph.D. Cell Biology, Molecular Biology, Biochemistry or related field with 2+ year of relevant experience or M.S. with 6+ years relevant experience.
- Experience mentoring bench scientists either directly or as a matrix team lead.
- Strong organizational, time management, communication, and interpersonal skills.
- Comfort in a fast-paced environment and ability to adjust workload based on changing priorities, coupled with a demonstrated eagerness to learn new things.
- A strong self-starter, independent thinker with strong attention to detail.

Desirable:
Hands on experience in expression, purification and characterization of recombinant proteins.
Hands-on experience in HTP-based binding assays and/or cell-based assay.
Hands-on experience in analytical methodologies for biophysical characterization.
Hands on experience in Phage or Yeast Display technology for optimization.
Experience in working in a BL-2 environment.
Why consider Novartis?
769 Million. That’s how many lives our products touched in 2020. And while we’re proud of that fact, in this world of digital and technological transformation, we must also ask ourselves this: how can we continue to improve and extend even more people’s lives?
We believe the answers are found when curious, courageous and collaborative people like you are brought together in an inspiring environment. Where you’re given opportunities to explore the power of digital and data. Where you’re empowered to risk failure by taking smart risks, and where you’re surrounded by people who share your determination to tackle the world’s toughest medical challenges.
Imagine what you could do at Novartis

**Division**
- NIBR

**Business Unit**
- BIOLOGICS NIBR

**Country**
- Switzerland

**Work Location**
- Basel

**Company/Legal Entity**
- Novartis Pharma AG

**Functional Area**
- Research & Development

**Job Type**
- Full Time

**Employment Type**
- Regular

**Shift Work**
- No

**Early Talent**
- No