Principal Medical Affairs

**Help us change lives**

At Exact Sciences, we’re helping change how the world prevents, detects and guides treatment for cancer. We give patients and clinicians the clarity needed to make confident decisions when they matter most. Join our team to find a purpose-driven career, an inclusive culture, and robust benefits to support your life while you’re working to help others.

**COMPANY OVERVIEW**

Exact Sciences is dedicated to delivering patient critical answers across the cancer journey from early detection to treatment decision making with a strong focus on people and an empathetic spirit, which fuels the company’s culture, driving them to create and deliver solutions rooted in the needs of patients, providers, and families. From earlier cancer detection to treatment guidance and monitoring, Exact Sciences are helping people get the answers they need to make more informed decisions across the cancer continuum. With a leading portfolio of products for earlier detection and treatment guidance, they help people face the most challenging decisions with confidence with a dedication to continuously innovate, combining scientific rigor with an open-minded approach to deliver the next big thing.

Exact Sciences is continuously expanding the pipeline with the aim of tackling a wider array of cancer tests through the following measures:

- Expanding the Oncotype IQ platform to include liquid and tissue-based tests, all with the goal of making cancer care smarter.
- Adapting biomarker-based technologies create a liquid biopsy capable of detecting cancers and precancers from a blood sample.
- Using their proven multi-marker approach to achieve analytical sensitivity needed to discriminate between normal and cancerous samples.
- Collaborating with world-class clinicians and scientists at Mayo Clinic to identify biomarkers associated with the 15 deadliest cancers.
- Building a cancer detection platform upon learnings from the development of Cologuard® (commercially available in the US only).

By 2020, Oncotype DX will have been used to guide treatment decisions for more than 1 million cancer patients worldwide in breast, prostate and colon cancer.

In July 2019 Exact Sciences acquired Genomic Health, a genetic cancer detection company based in Redwood City, California, for USD 2.8 billion, creating the leading global cancer diagnostics company.

In 2020 Exact Sciences acquired Thrive Earlier Detection Corp., a Massachusetts-based healthcare company, in a multi-billion-dollar deal, and Base Genomics, which has technology for DNA methylation analysis.

In February 2021 Exact Sciences announced the acquisition of Ashion Analytics, LLC (Ashion) from The Translational Genomics Research Institute (TGen), an affiliate of City of Hope. Ashion is a CLIA-certified and CAP-accredited sequencing lab based in Phoenix, Arizona with the genomics testing capabilities necessary to address the increasingly complex needs of clinical, academic, and biopharma customers focused on precision cancer treatments.

The company is based in the United States, with international headquarters in Zug, Switzerland.

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The International Medical Director, Screening Portfolio at Exact Sciences manages research and educational medical objectives, while supporting international commercial business and reimbursement objectives for novel assays which lead to improved treatment decisions. The position will be responsible for driving International medical & developmental strategy for new technologies in Screening. The International region includes Europe, Canada, Africa, Asia Pacific, Latin America.

Key responsibilities include creating clinical studies strategy, building international medical plans, engagement of selected key opinion leaders, planning of international advisory boards, developing international medical education programs, maintaining product/therapeutic area expertise, and delivering presentations and training internally.

**RESPONSIBILITIES / DUTIES**:

- Identify and engage international thought leaders in Screening (Colo-Rectal & Multi Cancer Early Detection) to conduct scientific discussions and gather insights related to screening and evidence generation.
- Assist in R&D and investigator-initiated studies as appropriate.
- Lead international Advisory Boards.
- Execute international medical education.
- Lead medical activities in international congress coordinating event planning and support slide developments.
- Developing medical slides, giving medical training presentations, and training in internal meetings and for partner distributors.
- Support international access & reimbursement with medical and scientific expertise.
- Assure compliance with relevant corporate policies and European regulatory requirements.

**Pivotal Experience & Expertise**
- Degree in Medicine/Medical Doctor is preferred. PhD, PharmD considered.
- 3 years + in therapeutic clinical research/affairs experience needed.
- 8 to 10 years of industry experience (w