Molecular and Computational Safety Scientist

vor 1 Tag

Basel, Schweiz Novartis Vollzeit

6000 That’s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients.
- The Pre-Clinical Safety (PCS) group in NIBR provides world class preclinical safety profiling and assessment for optimal drug discovery, development and commercialization, with state-of-the-art regulatory compliance.
- As a molecular and computational safety scientist, you will be involved in a wide range of projects within the Genome Safety section at Novartis, Preclinical Safety (PCS) department. In this role you will collaborate with multi-disciplinary scientists to support the safety of LMW compounds and Cell & Gene Therapy products within the Novartis Research and Development portfolio.-
**Commitment to Diversity & Inclusion**:

- Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve._

**Minimum requirements**
- Required skills: 
- Master’s degree or equivalent with work experience in molecular and computational biology as well as experience working in genome editing or viral research projects within academic and/or drug discovery settings.
-  Hands-on experience with molecular biology and biochemistry techniques (nucleic acid extraction, PCR, ddPCR / qPCR, western blot, cloning, cell culture). Prior experience in cytogenetics, viral integration site analysis, CRISPR off-target, library prep for NGS, chromosome conformation capture (3C, 4C, HiC) and/or rapid amplification of cDNA ends (RACE) is a plus.
-  Confidence working in a UNIX environment. Experienced with next generation sequencing data analysis and biostatistics. Solid programming skills in R or Python and/or previous experience in viral integration site analysis or CRISPR off-target is a plus.
-  Collaborative, flexible, critical thinking and strong team player.
-  Excellent organization and communication skills, independent, organized, and accurate working style, committed to high quality. 
- Fluent English (written and spoken)
- This role can be based in either Basel, Switzerland or Cambridge Mass. US.
- Why Novartis?
- 766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.
- We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.
- We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying
- Imagine what you could do here at Novartis**Division**
- NIBR

**Business Unit**
- Translational Medicine

**Country**
- Switzerland

**Work Location**
- Basel

**Company/Legal Entity**
- Novartis Pharma AG

**Alternative Country 1**
- USA

**Functional Area**
- Research & Development

**Job Type**
- Full Time

**Employment Type**
- Regular

**Shift Work**
- No

**Early Talent**
- No

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