Aktuelle Jobs im Zusammenhang mit Postdoc position in the development of in vitro models of the BBB to investigate the efficacy of innovative biotherapeutics against CNS diseases - Basel, Basel-Stadt - Bio Engineering Laboratory & Novartis
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Basel, Basel-Stadt, Schweiz Bio Engineering Laboratory & Novartis VollzeitIn this project, we aim at exploring how in vitro models can be leveraged to improve preclinical drug selection, in particular for gene therapy development. Building on the group expertise in blood-brain-barrier platforms, the postdoc will develop new in vitro models of the human and mouse blood-brain-barrier and benchmark the in vitro models for preclinical...
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Basel, Basel-Stadt, Schweiz Institute of Human Biology VollzeitAbout the Institute of Human Biology's ResearchOur FocusWe are committed to advancing human model systems in drug discovery and development, and personalized medicine. Our research focuses on the development of novel biobanking and in vitro model development methods, which enable us to better understand human biology and disease mechanisms.Main...
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Basel, Basel-Stadt, Schweiz Bio Engineering Laboratory & Novartis VollzeitJob description The postdoc will develop new cell-culture platforms and tisssue models intended to mimic the kidney microenvironment. He will use these platforms to culture stem-cell-derived renal cells to realize a renal tubular unit. The postdoc will then focus on the functional characterization of the tubular unit to confirm that the developed model...
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Basel, Basel-Stadt, Schweiz Bio Engineering Laboratory & Novartis VollzeitExplore the potential of in vitro models to enhance preclinical drug selection, focusing on gene therapy development. Leverage the group's expertise in blood-brain-barrier platforms to design and validate new in vitro models of the human and mouse blood-brain barrier. Collaborate with researchers at Novartis AG to evaluate the developed models' ability to...
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Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitYour position The purpose of the scholarships is to support you during the starting phase of your doctorate. Within the first six months of your scholarship, you will prepare a compelling funding application, which you will submit to the relevant bodies in order to continue your dissertation with third-party funding. Your profile The scholarships...
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Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitYour position The grant is intended to support a young graduate during the starting phase of his/her PhD research project. It is expected that he/she will develop a funding proposal during the first six months for applying to the Swiss National Science Foundation or other funding institutions. Your profile The scholarship is addressed to students...
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Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitThe purpose of the scholarships is to support you during the starting phase of your doctorate. Within the first six months of your scholarship, you will prepare a compelling funding application, which you will submit to the relevant bodies in order to continue your dissertation with third-party funding.Your profileThe scholarships are intended for graduates...
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Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitYour position The scholarships are meant to support graduates in the early stages of their PhD, during which they will develop research proposals for submission to a funding body such as the Swiss National Science Foundation in order to acquire financial support for the remaining duration of their PhD-projects. The payment of the second installment of...
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Development of In Vitro Kidney Models Specialist
Vor 4 Tagen
Basel, Basel-Stadt, Schweiz Bio Engineering Laboratory & Novartis VollzeitRole SummaryWe are seeking a highly motivated Postdoctoral Researcher to join our team at the Bio Engineering Laboratory & Novartis. The successful candidate will contribute to the development of innovative in vitro kidney models, collaborating with engineers and biologists to advance preclinical testing and drug development.The postdoctoral researcher will...
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Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitYour position The one-year start-up grant (application deadline: November 17, 2024; start date: April 1, 2025) is intended to contribute to living expenses during the elaboration phase of a dissertation project in literary studies. The aim of the start-up grant is to prepare and submit a competitive application for follow-up funding or for project...
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Senior Scientist for BBB In Vitro Platform Development
vor 13 Stunden
Basel, Basel-Stadt, Schweiz Bio Engineering Laboratory & Novartis VollzeitThis position involves the development of innovative in vitro models of the blood-brain barrier to enhance preclinical drug selection, particularly for gene therapy development. As a postdoctoral researcher, you will contribute to the design and validation of new in vitro models of the human and mouse blood-brain barrier, working closely with researchers at...
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Research Historian of the Basel Graduate School
Vor 3 Tagen
Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitCompany OverviewThe Basel Graduate School of History is a prestigious institution dedicated to fostering excellence in research and academic rigor. Our mission is to provide exceptional support to our students, enabling them to excel in their pursuit of knowledge.We are committed to creating a dynamic and inclusive environment that encourages intellectual...
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Institute of Human Biology Researcher
Vor 4 Tagen
Basel, Basel-Stadt, Schweiz Institute of Human Biology VollzeitAbout the Institute of Human Biology's TeamWho We AreWe are a dynamic and inclusive team of researchers and professionals who share a passion for advancing human model systems in drug discovery and development. Our team consists of experts in stem cell biology, engineering, and data science.Main ResponsibilitiesCollaborate with multidisciplinary experts to...
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Basel, Basel-Stadt, Schweiz Matterhorn Biosciences AG VollzeitMatterhorn Biosciences AG is a dynamic biotechnology company committed to improving patient outcomes through cutting-edge research and clinical trials. As an In Vitro Pharmacology Lead, you will play a critical role in developing innovative therapies for obesity and cardiometabolic conditions. This position involves collaborating with internal teams and...
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Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitYour position Antimicrobial resistance (AMR) is a global health concern. In recent decades, pan-resistant bacteria have emerged, rendering commonly available antibiotics ineffective. Consequently, many pivotal advancements in modern medicine are now under threat. As the development of new antimicrobials stagnates, there is an urgent need for alternative...
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Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitAntimicrobial resistance (AMR) is a global health concern. In recent decades, pan-resistant bacteria have emerged, rendering commonly available antibiotics ineffective. Consequently, many pivotal advancements in modern medicine are now under threat. As the development of new antimicrobials stagnates, there is an urgent need for alternative strategies to...
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Blood-Brain Barrier In Vitro Model Development Specialist
vor 13 Stunden
Basel, Basel-Stadt, Schweiz Bio Engineering Laboratory & Novartis VollzeitPursue a career in biomedical engineering by developing innovative in vitro models of the blood-brain barrier. This project aims to improve preclinical drug selection, particularly for gene therapy development. You will contribute to the design and validation of new in vitro models of the human and mouse blood-brain barrier, working closely with researchers...
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Professor of Gynaecological Endocrinology
Vor 4 Tagen
Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitAbout the PositionWe are seeking a visionary Professor of Gynaecological Endocrinology to join our faculty at The Biozentrum, University of Basel. As a leader in reproductive medicine, you will head the Unit of Reproductive Medicine / Gynaecological Endocrinology, inspiring creative thinking and action among your team members.Your ProfileProfound interest in...
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Director of Reproductive Medicine Unit
Vor 4 Tagen
Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitReproductive Medicine Leader WantedThe Biozentrum, University of Basel invites applications for the position of Director of Reproductive Medicine Unit. The successful candidate will be responsible for leading the unit, overseeing its operations, and implementing new ideas and initiatives.Your Skills and QualificationsStrong leadership skills and ability to...
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Basel, Basel-Stadt, Schweiz The Biozentrum, University of Basel VollzeitYour position The project aims to develop cartilage and osteochondral using nasal chondrocytes (cells in clinical use for repairing cartilage defects) and Melt electrowriting (MEW, i.e., an approach that combines electrospinning with 3D printing). In particular, the effect of scaffold architecture on nasal chondrocyte differentiation will be assessed....
Postdoc position in the development of in vitro models of the BBB to investigate the efficacy of innovative biotherapeutics against CNS diseases
vor 1 Woche
Job description
In this project, we aim at exploring how in vitro models can be leveraged to improve preclinical drug selection, in particular for gene therapy development. Building on the group expertise in blood-brain-barrier platforms, the postdoc will develop new in vitro models of the human and mouse blood-brain-barrier and benchmark the in vitro models for preclinical and clinical investigations. After validation of the models, the postdoc will work in close collaboration with researchers at Novartis AG to test whether the developed models can be used to expedite the selection of candidate therapeutics, in particular for gene therapy.
Your profile
The successful candidateshould have a background in bioengineering and biotechnology or related fields, with a preference for experience with microfluidics and advanced in vitro models, transport across endothelial barriers, and viral vectors. Experience in optical microscopy is highly beneficial. Further, knowledge of standard molecular biology techniques and NGS technologies will be considered advantageous for this position. Good communication skills and a proactive work attitude are required for working in the interdisciplinary field of preclinical testing and drug development. The Postdoc must be able to fluently communicate in English (oral and written) and be willing to work in a highly interactive and collaborative international environment. The researcher will work at the intersection of academic and industrial research with access to resources and expertise from both institutions.
Academic excellence, a professional work attitude, and a self-driven nature are expected. The position is fully funded for initially 2 years, an extension to up to 4 years is possible. The starting date is flexible but must be before 10-.
