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Organoid Researcher

vor 2 Wochen


Basel, Basel-Stadt, Schweiz Institute of Human Biology Vollzeit

Human Biology Research Associate

About the Role

We are seeking a highly skilled researcher to contribute to our mission of advancing more predictive human model systems. As a Senior Associate, you will be responsible for all aspects of our cell line and organoid biorepository and will contribute to further improving our capabilities for biobanking.

Our team in the Institute of Human Biology is dedicated to harnessing and advancing the use of human model systems in drug discovery and development, and personalized medicine. We bridge academic and pharmaceutical research, connecting biologists, engineers, and data scientists.

Key responsibilities include:

  1. Develop and Maintain Complex In Vitro Models: Establish and maintain master and working cell banks, as well as complex in vitro models, ensuring comprehensive documentation and tracking of model usage and storage conditions.
  2. Implement Quality Assurance Measures: Implement routine quality control measures, including contamination testing and cell line authentication, to maintain specimen integrity and advance QC processes to state-of-the-art levels for both cell lines and cIVMs.
  3. Ensure Regulatory Compliance: Ensure adherence to standard operating procedures, regulatory guidelines, and quality standards, while supporting ethical compliance in the use of embryonic stem cells, induced pluripotent stem cells, and cIVMs.
  4. Manage Specimen Lifecycles: Oversee the entire lifecycle of specimens, including cIVMs, from acquisition to distribution, ensuring efficient biosample fulfillment, customer communication, and inventory management.
  5. Develop Standard Operating Procedures: Conduct quality checks and handle tissue distribution, while developing standardized protocols for the isolation and culture of various cell types, such as endothelial cells and astrocytes, to support downstream applications and enhance cIVM capabilities.