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Cell Line Specialist
vor 1 Woche
Unlocking the Power of Human Biology
The PositionIn Roche's Pharmaceutical Research and Early Development Organisation (pRED), we make transformative medicines for patients in order to tackle some of the world's toughest unmet healthcare needs. At pRED, we are united by our mission to transform science into medicine.
You will join Roche's Institute of Human Biology (IHB), an organization within pRED whose goal is to harness and advance the use of human model systems in drug discovery and development, and personalized medicine. Our interdisciplinary research bridges academic and pharmaceutical research, connecting biologists, engineers, and data scientists.
We are seeking a skilled professional to contribute to our mission of advancing more predictive human model systems. As a Senior Associate, you will be responsible for all aspects of our cell line and organoid biorepository and will contribute to further improving our capabilities for biobanking.
- Develop and Sustain Cell Banks: Establish and maintain master and working cell banks, as well as complex in vitro models, ensuring comprehensive documentation and tracking of model usage and storage conditions.
- Implement Quality Control Measures: Implement routine quality control measures, including contamination testing and cell line authentication, to maintain specimen integrity and advance QC processes to state-of-the-art levels for both cell lines and cIVMs.
- Evaluate Regulatory Guidelines: Ensure adherence to standard operating procedures, regulatory guidelines, and quality standards, while supporting ethical compliance in the use of embryonic stem cells, induced pluripotent stem cells, and cIVMs.
- Oversee Specimen Lifecycle: Oversee the entire lifecycle of specimens, including cIVMs, from acquisition to distribution, ensuring efficient biosample fulfillment, customer communication, and inventory management.
- Develop Standardized Protocols: Conduct quality checks and handle tissue distribution, while developing standardized protocols for the isolation and culture of various cell types, such as endothelial cells and astrocytes, to support downstream applications and enhance cIVM capabilities.