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Molecular Biology Specialist

vor 1 Woche


Basel, Basel-Stadt, Schweiz F. Hoffmann-La Roche Gruppe Vollzeit

We foster diversity, equity, and inclusion at F. Hoffmann-La Roche Gruppe, representing the communities we serve. In healthcare, diversity is essential for success. We believe that good business means a better world.

The Position

We are looking for a talented postdoctoral fellow to investigate the molecular pathways driving human alveolar cell regeneration and function under disease conditions.

Key Responsibilities:

  • Cultivating human alveolar and airway organoids using high-throughput methods
  • Investigating disease-relevant conditions to identify those that mimic the disease molecular state
  • Characterizing phenotypes and molecules using techniques like immunofluorescence, flow cytometry, and scRNA-seq
  • Utilizing pharmacological modulators to understand pathways involved in alveolar cell regeneration and differentiation
  • Exploring how modulating identified signaling pathways impacts alveolar progenitor cells under disease conditions

Qualifications:

  • PhD in Molecular Biology, Cell Biology, Developmental Biology, Pharmacology, or a related field
  • Background in cell signaling, particularly Wnt pathways, and experience with organoid culture systems
  • Desirable proficiency in high-throughput screening techniques and data analysis
  • Desirable experience with genetic engineering and iPSC technology
  • Highly desirable proficiency in computational analysis and data interpretation
  • Excellent problem-solving skills and collaboration abilities

This position is sponsored by the F. Hoffmann-La Roche Gruppe Postdoctoral Fellowship Programme. Our aim is to build scientific leadership and collaborate with top researchers worldwide.