Computational Chemistry Expert
Vor 5 Tagen
Zenith Therapeutics is a pioneering force in drug discovery, redefining the approach to protein degradation through innovative computational methods. Our team has identified key ligases that govern the turnover of hard-to-drug transcription factors, converting these pairs into druggable protein-protein interfaces. With an initial focus on oncology and immune modulation, we are committed to advancing impactful precision medicines across multiple disease areas.
Headquartered in Switzerland, Zenith was created by Ridgeline Discovery, a Versant Ventures Discovery Engine, and is backed by leading investors in the biotech sector. We are seeking an experienced Computational Chemist to join our growing drug discovery team, driving cheminformatics and structure-based efforts across multiple programs – from library design to advanced optimization.
Key Responsibilities:
- Develop and implement the computational chemistry strategy in collaboration with internal stakeholders.
- Design and implement rational approaches for library creation, modeling of protein-protein interactions, and compound design.
- Analyze complex datasets to drive drug discovery decisions.
- Support drug discovery programs from hit identification to candidate selection.
Qualifications and Skills:
- Ph.D. in a relevant field and a strong background in computational chemistry.
- 5+ years of experience in the pharmaceutical or biotech industry focusing on small molecules.
- Deep understanding of drug discovery processes, medicinal chemistry, ADMET principles, and multiparameter compound optimization.
- Proven track record of impacting drug discovery projects in a biotech or pharmaceutical setting through creative computational chemistry approaches.
- Hands-on expertise in structure-based drug design approaches, tools, as well as cheminformatics and data analytics/visualization.
- Strong communication skills with the ability to build productive relationships and collaborations both internally and externally.
-
Advanced Computational Chemistry Position
Vor 4 Tagen
Basel, Basel-Stadt, Schweiz The Computational Chemistry List VollzeitJoin Our Team in Basel, SwitzerlandWe are seeking a highly qualified postdoctoral researcher to join our group at the Department of Chemistry, University of Basel, Switzerland. As a member of our team, you will contribute to cutting-edge research in theoretical and computational chemistry, working closely with our team to advance our understanding of complex...
-
Postdoctoral Researcher in Chemistry
Vor 4 Tagen
Basel, Basel-Stadt, Schweiz The Computational Chemistry List VollzeitWelcome to our job listing for a postdoctoral position in theoretical and computational chemistry! We are excited to offer this opportunity for a talented researcher to join our team at the Department of Chemistry, University of Basel, Switzerland.About Our Research:Our research group focuses on developing and applying advanced computational tools for...
-
Chemistry Department Job Opening
Vor 4 Tagen
Basel, Basel-Stadt, Schweiz The Computational Chemistry List VollzeitResearch Opportunities in Basel, SwitzerlandWe invite applications for a postdoctoral position in the Department of Chemistry at the University of Basel, Switzerland. Our research group focuses on theoretical and computational chemistry, with a particular emphasis on machine learning and molecular simulations.Your Role:You will work closely with our team to...
-
Theoretical Chemist Wanted
Vor 4 Tagen
Basel, Basel-Stadt, Schweiz The Computational Chemistry List VollzeitCCL Postdoctoral Position, Chemistry Department, Uni Basel, Switzerland (Group Meuwly)We are seeking a highly skilled postdoctoral researcher to join our group at the Department of Chemistry, University of Basel, Switzerland. The successful candidate will have a strong background in computational and theoretical chemistry.The main theme of our research is...
-
Basel, Basel-Stadt, Schweiz F. Hoffmann-La Roche AG VollzeitWe're looking for a highly experienced Library Enhancement, Data and Computational Chemistry Expert to join our team in Basel, Switzerland.In this role, you will leverage your expertise in cheminformatics, data science, and computational chemistry to develop and implement novel solutions to optimize small molecule screening activities and streamline data...
-
Computational Chemist
Vor 4 Tagen
Basel, Basel-Stadt, Schweiz FTS Food Technology Services AG VollzeitAt Zenith Therapeutics, we are redefining drug discovery through a cutting-edge approach to protein degradation. Our team has made significant breakthroughs in identifying key ligases that govern the turnover of hard-to-drug transcription factors, converting these pairs into druggable protein-protein interfaces.We are committed to advancing highly impactful...
-
Basel, Basel-Stadt, Schweiz Ridgeline Discovery GmbH VollzeitZenith Therapeutics is redefining drug discovery through a new approach to protein degradation. Our team has identified key ligases that govern the turnover of hard-to-drug transcription factors and convert these pairs into druggable protein-protein interfaces. With an initial focus on oncology and immune modulation, we are committed to advancing highly...
-
PhD Researcher in Medicinal Chemistry
vor 24 Stunden
Basel, Basel-Stadt, Schweiz Karlstad University VollzeitThe University of Basel, one of the world's top universities, is seeking a highly skilled PhD researcher to join its Department of Biomedicine and Department of Chemistry. The successful candidate will focus on developing novel modalities to target the PI3K-mTOR pathway in cancer research and immunobiology.Key ResponsibilitiesDesign, development, and...
-
Principal Scientist in Computational Approaches
Vor 5 Tagen
Basel, Basel-Stadt, Schweiz TN Switzerland VollzeitAt Zenith Therapeutics, we are committed to advancing impactful precision medicines across multiple disease areas. We are seeking a talented Principal Scientist to join our growing drug discovery team, contributing to the development of novel therapeutic approaches through cutting-edge computational methods.As a key member of our team, you will drive...
-
Computational Pharmacist
Vor 4 Tagen
Basel, Basel-Stadt, Schweiz Prime Life Sciences VollzeitJob OverviewWe are seeking a highly skilled researcher to join our team as a Postdoctoral Researcher in the field of computational drug discovery. This position offers an opportunity to work with state-of-the-art techniques and collaborate with a diverse group of researchers.About the Position:Develop and implement novel algorithms for drug design combining...
-
Basel, Basel-Stadt, Schweiz Karlstad University VollzeitAt Karlstad University, we are seeking a highly motivated and skilled Research Scientist to join our team in the Department of Biomedicine and Department of Chemistry. As a Research Scientist, you will play a key role in advancing our understanding of cancer biology and developing novel therapeutic strategies.Job DescriptionWe are looking for a talented...
-
Analytical Chemistry Expert
Vor 7 Tagen
Basel, Basel-Stadt, Schweiz TN Switzerland VollzeitAt TN Switzerland, we are committed to providing our clients with cutting-edge solutions in pharmaceutical forensics. Our team is dedicated to helping companies navigate complex regulatory landscapes and stay ahead of the competition. About the Position:We are seeking an experienced and highly motivated Analytical Chemistry Expert for a contract position in...
-
Molecular Glue Designer
Vor 4 Tagen
Basel, Basel-Stadt, Schweiz FTS Food Technology Services AG VollzeitWe are an international and diverse team at Zenith Therapeutics, passionate about advancing precision medicines across multiple disease areas. As a Computational Chemist, you will play a critical role in our mission, leveraging your expertise in computational chemistry to drive our cheminformatics efforts.Your responsibilities will include developing and...
-
Principle Chemist for Protein Degradation
Vor 5 Tagen
Basel, Basel-Stadt, Schweiz TN Switzerland VollzeitJoin our team at Zenith Therapeutics as a Principle Chemist for Protein Degradation! We are a dynamic and innovative company, pushing the boundaries of traditional drug discovery approaches through cutting-edge computational methods.As a key member of our team, you will contribute to the development of novel therapeutic approaches, leveraging your expertise...
-
Cheminformatics Specialist
Vor 4 Tagen
Basel, Basel-Stadt, Schweiz FTS Food Technology Services AG VollzeitWe are seeking an experienced Computational Chemist to join our growing team at Zenith Therapeutics. In this key role, you will lead our computational approaches for identifying and optimizing molecular glues.Our team has identified key ligases that govern the turnover of hard-to-drug transcription factors and convert these pairs into druggable...
-
Senior Scientist in Drug Discovery
Vor 5 Tagen
Basel, Basel-Stadt, Schweiz TN Switzerland VollzeitWe are seeking a highly skilled Senior Scientist to join our drug discovery team at Zenith Therapeutics. As a key member of our team, you will contribute to the development of novel therapeutic approaches, leveraging cutting-edge computational methods to drive innovation in protein degradation.Our company is headquartered in Switzerland and is backed by...
-
Global Regulatory Chemistry Specialist
vor 2 Wochen
Basel, Basel-Stadt, Schweiz myScience VollzeitGlobal Regulatory Chemistry SpecialistSyngentaPublished 27 February 2025Workplace Basel, North West Switzerland, SwitzerlandCategory Agronomy / Food ScienceChemistryPosition Regular Employment / Collaborator1. Location: Basel2. __vacancyopjusttionswidget.opt- Brand__ Syngenta Crop Protection3. Function Regulatory AffairsJob descriptionWe have an exciting...
-
Synthetic Chemist
vor 24 Stunden
Basel, Basel-Stadt, Schweiz Karlstad University VollzeitThe University of Basel's Department of Biomedicine and Department of Chemistry is seeking a talented synthetic chemist to join its PhD programme. As a PhD researcher, you will focus on developing novel chemical probes and degraders to dissect mechanisms of adverse effects in cancer and metabolism.Key ResponsibilitiesDesign and develop new chemical probes...
-
Global Regulatory Chemistry Specialist
Vor 6 Tagen
Basel, Basel-Stadt, Schweiz Syngenta Crop Protection VollzeitJob DescriptionWe have an exciting opportunity for a Global Regulatory Chemistry Specialist in our Regulatory team to enhance and align existing historical regulatory data, as well as contribute to qualitative and consistent value-extraction from Crop Protection product chemistry in support of our digital transformation and regulatory dossier...
-
Postdoctoral Fellowship in Process Chemistry
vor 2 Wochen
Basel, Basel-Stadt, Schweiz myScience VollzeitPostdoctoral Fellowship in Process ChemistrySyngentaPublished 28 February 2025Workplace Basel, North West Switzerland, SwitzerlandCategory ChemistryAgronomy / Food SciencePosition Senior Scientist / Postdoc1. Function Process Technology2. __vacancyopjusttionswidget.opt- Brand__ Syngenta Crop Protection3. Location: MuenchwilenJob descriptionPostdoctoral...