Cheminformatics Specialist

We are seeking an experienced Computational Chemist to join our growing team at Zenith Therapeutics. In this key role, you will lead our computational approaches for identifying and optimizing molecular glues.

Our team has identified key ligases that govern the turnover of hard-to-drug transcription factors and convert these pairs into druggable protein-protein interfaces. With an initial focus on oncology and immune modulation, we are committed to advancing highly impactful precision medicines across multiple disease areas.

You will work closely with our team to develop and implement the computational chemistry strategy, driving our cheminformatics efforts across multiple programs. Your expertise will be critical in designing and implementing rational approaches for library design, modeling of protein-protein interactions, and compound design.

Qualifications

• Ph.D. in a relevant field with a strong background in computational chemistry.
• 5+ years of experience in the pharmaceutical or biotech industry focusing on small molecules.
• Deep understanding of drug discovery processes, medicinal chemistry, ADMET principles, and multiparameter compound optimization.
• Proven track record of impacting drug discovery projects in a biotech or pharmaceutical setting through creative computational chemistry approaches.
• Hands-on expertise in structure-based drug design, cheminformatics, and data analytics/visualization.