Aktuelle Jobs im Zusammenhang mit Ophthalmology Discovery Scientist - Basel, Basel-Stadt - Roche
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Ophthalmology Discovery Scientist
vor 2 Monaten
We are seeking a highly motivated and talented Discovery Scientist to join our Ophthalmology Discovery Group at the Roche pRED Center Basel, Switzerland.
Key Responsibilities- Develop, optimize, and validate advanced histology, immunohistochemistry, immunofluorescence, and cell biology assays for ocular and brain tissues.
- Perform microscopy image processing and analysis, including AI-based image segmentation and cell-type quantification, using tools like ImageJ, CellProfiler, and Imaris.
- Use in vitro and in vivo models of ocular disease to develop discovery platforms and identify and validate potential drug targets and therapy strategies.
- Independently plan and execute laboratory research, analyzing data using established or new workflows.
- Commit to proactive and strategic collaboration with a team of experts to advance exploratory and preclinical projects, documenting methods, results, and writing reports rigorously.
- Communicate scientific progress through internal meetings and publications in peer-reviewed journals, and contribute to project management, external collaborations, and supervising postdoctoral fellows.
- Hold a PhD in molecular biology, cell biology, biochemistry, bioengineering, biotechnology, synthetic biology, or a related relevant field, with postdoctoral experience preferred.
- Have hands-on experience with in vitro and in vivo ocular models, and experience with large animal models is a plus.
- Hold an LTK-1, FELASA B, or similar accreditation and have expertise in tissue processing and IHC, ICC/IF assays, and imaging processing and analysis, including AI-based processes.
- Have expertise in ocular AAV transduction (a plus) and be well-organized and committed to formal record-keeping.
- Be a team player who fosters a collaborative spirit with other scientists and colleagues, with excellent organization skills and proficiency in multi-tasking in a fast-paced environment.
- Be fluent in English with good presentation and communication skills, and demonstrate a track record of completing research projects and managing teams, with a strong publication record.
At Roche, more than 100,000 people across 100 countries are pushing back the frontiers of healthcare. Working together, we've become one of the world's leading research-focused healthcare groups. Our success is built on innovation, curiosity, and diversity.
Basel is the headquarters of the Roche Group and one of its most important centres of pharmaceutical research. Over 10,700 employees from over 100 countries come together at our Basel/Kaiseraugst site, which is one of Roche`s largest sites.
We believe in the power of diversity and inclusion, and strive to identify and create opportunities that enable all people to bring their unique selves to Roche.
Roche is an Equal Opportunity Employer.
