Senior Medicinal Chemistry Strategist

vor 1 Monat


Basel, Basel-Stadt, Schweiz Ridgeline Discovery GmbH Vollzeit

Ridgeline Discovery GmbH is a leading biotech company that creates and operates innovative companies in partnership with entrepreneurs, industry experts, and academics.

About the Role

We are seeking an experienced Senior Medicinal Chemistry Strategist to lead high-impact small molecule drug discovery projects. This role provides an exciting opportunity to shape medicinal chemistry strategy across novel therapeutic programs within a collaborative, multi-disciplinary environment.

Key Responsibilities
  • Collaborate with senior leadership to define and execute medicinal chemistry strategy across multiple early discovery and lead optimization programs.
  • Oversee medicinal chemistry efforts within Ridgeline's portfolio companies, advancing multiple projects from early discovery through clinical candidate nomination.
  • Apply advanced, multi-parameter optimization approaches to drive SAR, ADME, and efficacy in target molecules.
  • Define project goals, set key scientific milestones, and ensure that programs remain on track through critical decision-making.
Requirements
  • Ph.D. in Chemistry, Medicinal Chemistry, or a related field with 10+ years of experience in medicinal chemistry and drug discovery, preferably within the biotech or pharmaceutical industry.
  • Demonstrated expertise in synthetic and medicinal chemistry, with a proven track record of advancing drug discovery programs from target ID to clinical candidate stage.
  • Strong publication and/or patent record in the field of drug design, reflecting significant contributions to medicinal chemistry and hit-to-lead optimization.
  • Experience in leading external partnerships with CROs and managing multidisciplinary project teams.
What We Offer
  • A competitive salary range of CHF 120,000 - 180,000 per year, depending on experience.
  • An international and diverse team with talented and passionate people.
  • An innovative and creative environment.
  • The opportunity to develop your skills and career in a fast-paced and dynamic environment.


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