Principal Scientist

Summary Location: Basel, Switzerland Full time, onsite, #LI-Onsite The Oncology Translational Research (OTR) group within Novartis Biomedical Research seeks a highly motivated lab head to drive the translational strategy for early clinical radioligand therapy (RLT) programs. The role involves collaborative work with various groups across the drug development spectrum, including drug discovery, data science, and early clinical development groups. The successful candidate will be responsible for leading a team and will be tasked with the design & execution of preclinical translational studies and clinical biomarker plans. About the Role About the role: The Oncology Translational Research (OTR) group within Novartis Biomedical Research seeks a highly motivated lab head to drive the translational strategy for early clinical radioligand therapy (RLT) programs. The role involves collaborative work with various groups across the drug development spectrum, including drug discovery, data science, and early clinical development groups. The successful candidate will be responsible for leading a team and will be tasked with the design & execution of preclinical translational studies and clinical biomarker plans. Key responsibilities: - Lead a research team and collaborate with groups across BR Oncology - Contribute to biomarker strategies and supervise translational experimental plans for various RLT drug discovery programs - Design and conduct translational studies, dissect the biological mechanisms driving response and resistance to RLT, and develop rational drug combinations. - Mentor and develop associates with various levels of experience Essential Requirements: - Ph.D. in molecular, cellular, cancer biology or related fields. - Minimum 2 years of Postdoctoral and/or industry experience in an Oncology/Cancer biology relevant field - Recognised academic publication record - Deep understanding of cancer cell biology, familiarity with innovative cell and molecular biology techniques. - Excellent creative thinking and problem-solving skills, scientific curiosity. - Proficiency in working collaboratively and flexibly on various projects - Strong communication skills, at ease with conveying complex scientific concepts Desirable Requirements: - Strong foundational knowledge and experience working on cell death mechanisms, experience in the field of DNA damage response and repair, radiobiology or RLT. - Expertise in prostate cancer biology - Proficiency with data mining and computational skills. - Track record in managing a research team and scientific projects Accessibility and accommodation Novartis is committed to working with and providing reasonable accommodation to all individuals. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the recruitment process, or in order to receive more detailed information about the essential functions of a position, please send an e-mail to E-Mail schreiben and let us know the nature of your request and your contact information. Please include the job requisition number in your message Why Novartis: Helping people with disease and their families takes more than innovative science. It takes a community of smart, passionate people like you. Collaborating, supporting and inspiring each other. Combining to achieve breakthroughs that change patients’ lives. Ready to create a brighter future together? https://www.novartis.com/about/strategy/people-and-culture Benefits and Rewards: Read our handbook to learn about all the ways we’ll help you thrive personally and professionally: https://www.novartis.com/careers/benefits-rewards