Systems Pharmacology Internship Antibiotics

Vor 2 Tagen


Basel, Schweiz LYO-X GmbH Vollzeit

Simulation software for antibiotics effect prediction

**Project**:
Antibiotics resistance is a huge issue that is also getting more public awareness due to its criticality. An important part of addressing this problem is the correct usage of antibiotics. For this one has to know if an antibiotic is effective against a certain bacterial strain and how it should be dosed. We are implementing a software platform that allows users to predict the probability of successful treatment based on the bacterial strain and the type of drug and the dose and regimen. This software should be accessible via a web interface that is programmed in R and Shiny.

**Internship Goals**:

- Implement a mathematical model of antibiotics pharmacokinetics.
- Implement a mathematical model of antibiotics effect.
- Develop an interface in shiny for the mathematical models.
- Rigorous testing of the interface for usability.

**Requirements**:

- Rigorous, excellent analytical skills, pro-active.
- Entrepreneurial spirit.
- Good at communication of scientific topics.
- Proficient in oral and written English.
- Good mathematical and statistical skills.
- Expert in scientific programming using R and Shiny.
- User interface design.

**Languages**:
English (Advanced)

**Location**:
Basel. Remote work possible after evaluation of situation.

**Company**:
LYO-X is a Swiss company located in Basel providing global consulting and Systems Pharmacology modelling services dedicated to the preclinical and clinical development of biologics and cell-based therapies.

**Contact**:



  • Basel, Schweiz LYO-X GmbH Vollzeit

    Software for animal-to-human scaling of biotherapeutics **Project**: Animal-to-human scaling of novel biotherapeutics is an important step in drug development. We want to develop a software that integrates existing data on preclinical and clinical pharmacokinetics of different biotherapeutic formats with mathematical models. The software should be able to...


  • Basel, Schweiz LYO-X GmbH Vollzeit

    Modelling of Iron Metabolism **Project**: Iron is essential for life on Earth and critical for human health. It enables oxygen transport via haemoglobin, supports cellular energy production, and plays a role in enzyme function and detoxification. A lack of iron causes anaemia, leading to fatigue and weakness, while excess iron can result in organ...


  • Basel, Schweiz Hengrui Europe Therapeutics AG Vollzeit

    **Job Title**: Director, Clinical Pharmacology **Reports to (Title)**: Department Head of Clinical Pharmacology & Early Development **Location**: Basel Switzerland **Direct Reports**: TBD **Department**: Clinical Pharmacology & Early Development **About Hengrui**: The Hengrui ex-China organization drives the development and commercialization of the...


  • Basel, Schweiz LYO-X GmbH Vollzeit

    Quantitative Systems Pharmacology Modeler Are you a highly motivated data scientist and mathematical modeler with a Masters or PhD degree who wants to impact drug development today! If you have great computational skills and are excited to use them to tackle complex biology underlying diseases; then LYO-X is the right place for you! LYO-X is an established...


  • Basel, Schweiz Idorsia Pharmaceuticals Ltd. Vollzeit

    **About Idorsia Pharmaceuticals Ltd** Idorsia Ltd is reaching out for more - We have more ideas, we see more opportunities and we want to help more patients. In order to achieve this, we want to develop Idorsia into one of Europe’s leading biopharmaceutical companies, with a strong scientific core. Headquartered in Switzerland - a European biotech hub -...


  • Basel, Schweiz Novartis Vollzeit

    390829BR **Internship in Biologics Drug Product Development**: Switzerland **About the role** We’re looking for an enthusiastic and motivated recent postgraduate in a pharmaceutical sciences-related field of science (e.g., biology, chemistry, biotechnology) with experience in drug delivery systems. We offer a 6-8-month Internship in our Biologics Drug...


  • Basel, Schweiz Hengrui Europe Therapeutics AG Vollzeit

    **Job Title**: Associate Director or Director of Pharmacometrics **Reports to (Title)**: Head of Pharmacometrics **Location**: Basel Switzerland **Direct Reports**: No **Department**: Clinical Pharmacology & Early Development **About Hengrui**: The Hengrui ex-China organization drives the development and commercialization of the Hengrui innovative...


  • Basel, Schweiz Bayer Vollzeit

    **At Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where ,Health for all, Hunger for none’ is no longer a dream, but a real possibility. We’re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our...


  • Basel, Schweiz Hawker Pacific Vollzeit

    Summary: Since 1967, Jet Aviation has been crafting flight in its smoothest form. From one hangar in Basel, Switzerland, to some 4,000 employees, and some 50 locations worldwide. Aircraft Management, Aircraft Sales, Charter, Completions, Defence, FBO, Fixed and Rotary Wing Maintenance, and Staffing. Behind every seamless Jet Aviation experience, is a team of...


  • Basel, Schweiz Universität Basel Vollzeit

    The Swiss Tropical and Public Health Institute (Swiss TPH) is a world-leading institute in global health with a particular focus on low - and middle-income countries. Associated with the University of Basel, Swiss TPH combines research, education and services at local, national and international levels. 950 people from 80 nations work at Swiss TPH focusing...


  • Basel, Schweiz Jet Aviation AG Vollzeit

    Our Engineering Technical Documentation Team is looking for a strong writer to support us in delivering aircraft documentation (maintenance and operation manuals). Under supervision of the tutor and using templates and guidelines, you have the opportunity to gain professional experience in an interesting and exciting working environment. -...


  • Basel, Schweiz Universität Basel Vollzeit

    The Swiss Tropical and Public Health Institute (Swiss TPH) is a world-leading institute in global health with a particular focus on low - and middle-income countries. Associated with the University of Basel, Swiss TPH combines research, education and services at local, national and international levels. 950 people from 80 nations work at Swiss TPH focusing...


  • Basel, Schweiz Novartis Vollzeit

    392463BR **TM Academy Fellow in Preclinical Safety**: Switzerland **About the role** Through the TM Academy, you will gain valuable training and experience within an international multi-cultural Biomedical Research environment. In parallel to your Academy learning, your core focus will be to contribute to the Preclinical Safety group within Translational...

  • E-commerce Assistant

    vor 3 Monaten


    Basel, Schweiz Tally Weijl Vollzeit

    We're here to make you feel sexy, empowered & UNSTOPPABLE. Founded in 1984, Tally Weijl has been on a crazy journey to celebrate fashion, independence, fun, love, & community for close to 40 years. Today we’re present in 35 markets with over 700+ stores, online presence, and 3m+ fans across social channels. Show us how #UNSTOPPABLE you are! We are...


  • Basel, Schweiz Novartis Vollzeit

    Your responsibilities: - contribute to the generation of disease models in complex 3D cell culture systems using in vitro differentiation - present your results at internal meetings, discuss your progress and get an impression about ongoing projects in your immediate environment **Commitment to Diversity & Inclusion**: - Novartis is committed to building...


  • Basel, Schweiz Hawker Pacific Vollzeit

    Summary: Since 1967, Jet Aviation has been crafting flight in its smoothest form. From one hangar in Basel, Switzerland, to some 4,000 employees, and some 50 locations worldwide. Aircraft Management, Aircraft Sales, Charter, Completions, Defence, FBO, Fixed and Rotary Wing Maintenance, and Staffing. Behind every seamless Jet Aviation experience, is a team of...


  • Basel, Schweiz Jet Aviation AG Vollzeit

    Since 1967, Jet Aviation has been crafting flight in its smoothest form. From one hangar in Basel, Switzerland, to some 4,000 employees, and some 50 locations worldwide. Aircraft Management, Aircraft Sales, Charter, Completions, Defence, FBO, Fixed and Rotary Wing Maintenance, and Staffing. Behind every seamless Jet Aviation experience, is a team of...

  • Student / Intern

    vor 1 Woche


    Basel, Schweiz Oracle Vollzeit

    Student / Intern-220006SS **Applicants are required to read, write, and speak the following languages**: English **Preferred Qualifications** This is a six-month internship position at Oracle Labs Zurich. The position will work for research and early development projects related to systems and techniques for data processing, data analysis,...


  • Basel, Schweiz Hengrui Europe Therapeutics AG Vollzeit

    **Job Title**: Associate Director or Director of Bioanalytical Sciences **Reports to (Title)**: Head of Bioanalytical Sciences **Location**: Basel Switzerland **Direct Reports**: No **Department**: Clinical Pharmacology & Early Development **About Hengrui**: The Hengrui ex-China organization drives the development and commercialization of the Hengrui...


  • Basel, Schweiz Hengrui USA Vollzeit

    **Reports to (Title): Head of Global Pharmacovigilance** **Location: Global/USA/Europe** **Exempt/Non-Exempt: Exempt** **Direct Reports : None** **Department: Pharmacovigilance** The Hengrui ex-China organization drives the development and commercialization of the Hengrui innovative medicines portfolio for the US, Europe and Japan. Our ex-China team drives...