Research Associate, Discovery Technologies
vor 2 Monaten
Overview:
If you have an interest in any of the following areas noted below, we will give you hands-on educational experience within a high paced Drug discovery environment.
**Responsibilities**:
- You will employ various technologies to identify and validate targets of molecular glue degraders within our Early Discovery workflow, a skillset with broad applicability in a range of drug discovery approaches.
- You will implement approaches for CRISPR/Cas9 KO/KI, flow cytometry/cell sorting, luminescence-based assays, immunoprecipitation/western blotting, and sequencing.
- You will play a role in the engineering of a degron tool in a target of interest via CRISPR editing of its endogenous locus, and use MGDs to elicit its degradation via the CRBN machinery.
- You will collaborate with different functions within the company and attend and present your data at team and project meetings.
Qualifications:
- Our preference is for a student currently in a master’s degree program in Cell Biology, Molecular Biology, or a life science field.
- Proficiency in English (written and spoken).
- Strong desire to learn the most advanced approaches in drug discovery and targeted protein degradation.
- Previous experience with mammalian cell culture, molecular biology / biochemical techniques (e.g. Western Blot, DNA extraction, PCR, CRISPR CAS9) and experience in working in a sterile environment (BSL2 standards) are required. Prior experience with handling of lentivirus and sequencing is desirable.
- You are a fast learner and enjoy working in a team-based environment.
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