Research Associate, Discovery Technologies
Vor 4 Tagen
**Research associate, discovery technologies - 6 Month Internship**
Location: Basel, Switzerland
If you have an interest in any of the following areas noted below, we will give you hands-on educational experience within a high paced Drug discovery environment.
Discovery Technologies
Key responsibilities:
- You will employ various technologies to identify targets of molecular glue degraders - a skillset with broad applicability in a range of drug discovery approaches.
- You will implement and compare pooled and arrayed approaches for CRISPR/Cas9 KO screens utilizing techniques such as flow cytometry, luminescence-based assays, western blotting, and sequencing.
- You will establish complex immunoprecipitation assays as an orthogonal approach to CRISPR/Cas9 KO screening.
- You will collaborate with different functions within the company and attend and present your data at team and project meetings.
Qualifications:
Our preference is for a student currently in a master’s degree program in Cell Biology, Molecular Biology, or a life science field.
Proficiency in English (written and spoken).
- Strong desire to learn the most advanced approaches in drug discovery and targeted protein degradation.
- Previous experience with mammalian cell culture, molecular biology / biochemical techniques (e.g. Western Blot, DNA extraction, PCR) are required. Prior experience with generation of lentivirus (working under BSL2 standards) and sequencing is desirable.
- Is a fast learner and enjoys working in a team-based environment.
Monte Rosa Therapeutics rational approach in targeting disease-causing proteins for degradation will deliver pioneering therapies for cancer and other diseases. Delivering this new generation of treatments to the patients requires a conceptual change. Monte Rosa recognizes this urgent need and is missioned to develop innovative protein degraders as a solution. Combining deep knowledge, insight and leading-edge science, our integrated engine is built for that purpose.
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