Principal Scientist

Vor 3 Tagen


Basel, Schweiz Novartis Vollzeit

390562BR

**Principal Scientist - Drug Discovery Glomerulonephritis (80-100%*)**:
Switzerland

**About the role**

Location: Basel, Switzerland
Full time, onsite, #LI-Onsite
The Immunology (IMM) department is accommodated within the Biomedical Research department of Novartis and works in collaboration with colleagues from Novartis Research and Development on several therapeutic areas with high unmet need, including autoimmune and inflammatory kidney diseases. Using a diverse array of approaches and ground breaking technology, IMM strives to develop drugs that improve the lives of individuals suffering from autoimmune and inflammatory kidney diseases for which there is currently no cure. At Novartis we have a bold ambition to transform the lives of millions of people living with such diseases.
We are seeking an innovative, independent and dynamic Principal Scientist with broad expertise in nephrology and immunology to join a discovery biology team focused on developing innovative therapeutic agents in the area of glomerulonephritis.
Your responsibilities will include:

- Contribute to the Biomedical Research drug discovery process with the goal to discover and develop novel therapeutic treatment options for patients with glomerulonephritis.
- Lead drug discovery projects in the renal disease space, propose and champion new targets and novel approaches for disease treatment.
- Contribute to translational research activities and mechanism of action studies to support ongoing clinical development programs
- Design and execute in vitro and in vivo research plans to evaluate targets modulating glomerulonephritis indications.
- Collaborate with other scientists in a global matrixed dynamic environment fostering innovation and advance project activities. Develop and maintain external relationships/contacts.

**Commitment to Diversity & Inclusion**:

- We are committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve._

**Role Requirements**

What you will bring to the role:

- A PhD and/or MD degree with Postdoctoral experience and a minimum of three years of research in renal biology and/or immunology, preferably in the pharmaceutical / biotechnology industry or academia.
- In-depth knowledge of pathophysiology of autoimmune and inflammatory glomerular diseases, especially around the role of pathogenic autoantibodies in disease i.e. expert in B cell biology, immune complex mediated renal diseases, autoantibody mediated effector function and inflammatory pathways in renal diseases.
- A track record of leading drug discovery projects and working alongside disease areas specialists to bring mechanistic target biology and target validation understanding for renal diseases.
- A proven scientific impact on innovation through a solid publication track record and strong external scientific network with academic experts.
- Excellent oral and written English communication skills, with an ability to effectively interact with people in a dynamic matrix environment, both internally and externally
- Experience in leading and mentoring associates and cross-functional teams

Why Novartis:
Our purpose is to reimagine medicine to improve and extend people’s lives and our vision is to become the most valued and trusted medicines company in the world. How can we achieve this? With our people. It is our associates that drive us each day to reach our ambitions. Be a part of this mission and join us

We offer plentiful benefits, state-of-the art facilities
and helpful resources - all designed to help you

Accessibility and accommodation

**Division**

Biomedical Research

**Business Unit**

IMMUNOLOGY - NIBR

**Work Location**

Basel

**Company/Legal Entity**

Novartis Pharma AG

**Functional Area**

Research & Development

**Job Type**

Full Time

**Employment Type**

Regular

**Shift Work**

No

**Early Talent**

No


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