Phd Position in Normal Tissue Radiobiology of Spatially Fractionated Radiation Therapy

vor 3 Wochen


Bern, Schweiz Universität Bern Vollzeit

The Institute of Anatomy at the University of Bern is part of the Faculty of Medicine and plays a pivotal role in research and education. With responsibilities in the study programmes of Human Medicine, Dentistry, Pharmaceutical Sciences, Biomedical Engineering, and Veterinary Medicine, the institute hosts ten independent but highly collaborative research groups. These groups focus on biomedical research in diverse fields such as Developmental Biology and Regeneration, Immunobiology, Angiogenesis, Cancer, and Spatially Fractionated Radiation Therapy.

The MIRACLE project, funded by the Swiss National Science Foundation (grant number: 10002984), brings together leading experts in radiation oncology, biology, and medical physics. It aims to translate breakthroughs in microbeam and minibeam radiation therapy into clinically viable systems, leveraging immune activation and vascular modulation to enhance tumor control while protecting healthy tissues. Collaborating with international partners, the project integrates advanced technologies to transform clinical radiotherapy.

Tasks
- Conduct toxicity studies to establish safe valley and peak dose thresholds for various sub-mm SFRT configurations.
- Perform acute toxicity assessments in animal models, focusing on skin and vascular responses.
- Utilize fractionated Conv-RT techniques as a baseline to compare sub-mm SFRT outcomes and establish Biologically Effective Doses (BED).
- Investigate dose-response relationships by conducting systematic dose escalation studies for valley and peak doses.

**Requirements**:

- Master's degree in biomedical sciences, molecular biology, biology, biochemistry, immunology, radiation biology, genetics or related discipline.
- Experience working with in mice models is a must.
- Experience working with the Chick Chorioallantoic Membrane (CAM) model is desired.
- Experience working with radiation is highly desired.
- Experience with normal tissue radiotoxicity is highly desired.
- Experience studying vascular effects in general is desired.
- Proficiency in laboratory techniques including histopathological analysis, cytokine profiling, functional assays, immunohistochemistry, and imaging techniques for tissue damage assessment.
- Proficiency in English as it will be the main language of communication.
- Speaking German is an asset.

We offer
- An inspiring and supportive research environment with state-of-the-art facilities and opportunities for collaboration and continuous education.
- The chance to present your results at international conferences.
- Engagement in an interdisciplinary, international, and dynamic team comprising biologists, physicists, and medical doctors.
- A safe, inclusive, and supportive research environment that values diversity and welcomes minorities.
- Equal opportunities provided by the University of Bern, with a strong commitment to diversity and excellence.

Interested?

**Application Package**
1.** Curriculum Vitae**, including list of publications.
2.** Letter of Motivation**, detailing your suitability for this position. Focus on describing your previous research experience, including an overview of your techniques, methods that you have used in previous research work.
3. **Copy of master's degree Certificate**.
4. **Two reference letters**.
- Legal Notice



  • Bern, Schweiz Universität Bern Vollzeit

    The Institute of Anatomy at the University of Bern is part of the Faculty of Medicine and plays a pivotal role in research and education. With responsibilities in the study programmes of Human Medicine, Dentistry, Pharmaceutical Sciences, Biomedical Engineering, and Veterinary Medicine, the institute hosts ten independent but highly collaborative research...


  • Bern, Schweiz Universität Bern Universität Bern Vollzeit

    **Postdoctoral Position in Spatially Fractionated Radiation Therapy** **100%**: The Institute of Anatomy of the University of Bern is part of the Faculty of Medicine and has a teaching assignment in the study programmes of Human Medicine and Dentistry, as well as Pharmaceutical Sciences, Biomedical Engineering, and Veterinary Medicine. Eleven independent but...


  • Bern, Schweiz Universität Bern Universität Bern Vollzeit

    **Postdoctoral Position in Spatially Fractionated Radiation Therapy** **100%**: The Institute of Anatomy of the University of Bern is part of the Faculty of Medicine and has teaching responsibilities in the study programmes of Human Medicine, Dentistry, Pharmaceutical Sciences, Biomedical Engineering, and Veterinary Medicine. Ten independent but highly...


  • Bern, Schweiz Universität Bern Vollzeit

    The Institute of Anatomy of the University of Bern is part of the Faculty of Medicine and has a teaching assignment in the study programmes of Human Medicine and Dentistry, as well as Pharmaceutical Sciences, Biomedical Engineering, and Veterinary Medicine. Eleven independent but highly cooperative working groups conduct biomedical research in the fields of...


  • Bern, Schweiz Universität Bern Vollzeit

    The Institute of Anatomy of the University of Bern is part of the Faculty of Medicine and has teaching responsibilities in the study programmes of Human Medicine, Dentistry, Pharmaceutical Sciences, Biomedical Engineering, and Veterinary Medicine. Ten independent but highly collaborative working groups conduct biomedical research in the fields of Didactic...

  • Phd Position

    Vor 5 Tagen


    Bern, Schweiz Universität Bern Universität Bern Vollzeit

    **PhD position** **Interpretability-Guided Deep Learning for Medical Image Analysis: Applications to Medical Image Classification, Retrieval and Segmentation**: Your job: In this project supported by the Swiss National Science Foundation, your role is to research innovative ways to employ information stemming from interpretability methods used in deep...


  • Bern, Schweiz Universität Bern Universität Bern Vollzeit

    **PhD student position in Cell Biology** **100 %**: Laboratory of Oral Cell Biology at the Department of Oral Surgery and Stomatology, University of Bern, Switzerland starting date upon agreement The research of the Laboratory of Oral Cell Biology at the Department of Oral Surgery and Stomatology, University of Bern, Switzerland answers clinically oriented...


  • Bern, Schweiz Universität Bern Vollzeit

    Laboratory of Oral Cell Biology at the Department of Oral Surgery and Stomatology, University of Bern, Switzerland starting date upon agreement The research of the Laboratory of Oral Cell Biology at the Department of Oral Surgery and Stomatology, University of Bern, Switzerland answers clinically oriented mechanistic questions related to oral hard and soft...

  • Phd Position

    Vor 3 Tagen


    Bern, Schweiz Universität Bern Universität Bern Vollzeit

    **PhD Position**: Applications are invited for a PhD position available at the Department for BioMedical Research, Oncology - Thoracic Malignancies Research Program, (PD Dr. Thomas M. Marti Lab), University of Bern, Switzerland One PhD position is available to investigate how modulation of the lactate metabolism mechanisms affects the response of cancer...

  • Phd Position

    Vor 3 Tagen


    Bern, Schweiz Universität Bern Vollzeit

    Applications are invited for a PhD position available at the Department for BioMedical Research, Oncology - Thoracic Malignancies Research Program, (PD Dr. Thomas M. Marti Lab), University of Bern, Switzerland One PhD position is available to investigate how modulation of the lactate metabolism mechanisms affects the response of cancer cells to radio We...


  • Bern, Schweiz Universität Bern Universität Bern Vollzeit

    **PhD position geochemistry**: One PhD position is available in Isotope Geology at the Institute of Geological Sciences at the University of Bern. This PhD project will focus on sublithospheric diamonds and ultradeep xenoliths from the Jagersfontein kimberlite, South Africa. Through constraining the nature and variation of compositions of this material -...


  • Bern, Schweiz University of Bern Vollzeit

    The Artificial Intelligence in Medical Imaging (AIMI) lab at the University of Bern's ARTORG Center for Biomedical Engineering Research invites applications from excellent scientists and engineers with a strong background in machine learning and computer vision to work on innovative methods in the domains of medical image computing.We are looking for...


  • Bern, Schweiz Insel Gruppe Vollzeit

    **_Project background:_**: - Project/aims/to do's: Starting point of your PhD project is a group of patients suffering from ultra-rare inborn errors of metabolism (IEM) which cause a disruption of central energy-conserving pathways such as the tricarboxylic acid (TCA) cycle and the malate aspartate shuttle (MAS). Malate dehydrogenase 2 (MDH2) deficiency is...


  • Bern, Schweiz Universität Bern Vollzeit

    One PhD position is available in Isotope Geology at the Institute of Geological Sciences at the University of Bern. This PhD project will focus on sublithospheric diamonds and ultradeep xenoliths from the Jagersfontein kimberlite, South Africa. Through constraining the nature and variation of compositions of this material - combined with the timing of...

  • Phd Student

    vor 7 Monaten


    Bern, Schweiz Insel Gruppe Vollzeit

    **Medical division cancer** **Department of Medical Oncology**: *** **100 % | in Bern**: *** **Entry immediately or as agreed upon** **Limited for 3 years**: *** Our research group studies epigenetic regulators in blood and patient-derived cancer tissue, focusing on Lung and Head and Neck cancers. We have ongoing clinical trials in which we are...


  • Bern, Schweiz Insel Gruppe Vollzeit

    Project background and aims: MRI of peripheral nerves, MR neurography, is a complementary and non-invasive diagnostic tool for evaluating peripheral nerve diseases. It enables morphological investigation of proximal and deeply situated nerve segments but is limited by the MRN sequence characteristics, such as being 2-D with limited anatomical coverage due to...


  • Bern, Schweiz Universität Bern Universität Bern Vollzeit

    **PhD Position in Ultrafast Spectroscopy of Quantum Materials** **100%**: A PhD project is available in the Nonlinear Optics group at the Institute of Applied Science - University of Bern. The research activity of our group exploits ultra-short pulses of laser light to investigate and manipulate the properties of complex solids. Our focus is to explore the...

  • Phd Student Position

    vor 1 Woche


    Bern, Schweiz Universität Bern Universität Bern Vollzeit

    **PhD Student Position**: **Workplace**: Department of Ophthalmology, Inselspital, University of Bern **Project Title**: Organoid-based modelling of human retinal degeneration / regeneration The Department of Ophthalmology is offering a PhD student position in the field of neuroscience/cell biology. The group's research interest is focused on the...


  • Bern, Schweiz Universität Bern Universität Bern Vollzeit

    **PhD position at University of Bern: Laboratory Analogue for the Surface of Icy Moons**: The vast majority of celestial objects in our outer solar system are bodies with icy surfaces (ice moons, Trans-Neptunian Objects, and comets). The surface of these objects directly interacts with the space environment and thus is open to in-situ or remote sensing...


  • Bern, Schweiz Universität Bern Universität Bern Vollzeit

    **PhD student position in the fields of cell and structural biology**: **The project** **The Ph.D. Position** **Requirements**: - Master of Science or Master of Medicine degree - Interest in the cell biology of organelles, lipids, and membranes - Excellent skills in oral and written English - Ability to work independently and to plan and direct own work -...