Molecular and Computational Safety Scientist

vor 11 Stunden


Basel, Schweiz Novartis Vollzeit

6000 That’s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to help produce therapeutic breakthroughs for patients.
- The Pre-Clinical Safety (PCS) group in NIBR provides world class preclinical safety profiling and assessment for optimal drug discovery, development and commercialization, with state-of-the-art regulatory compliance.
- As a molecular and computational safety scientist, you will be involved in a wide range of projects within the Genome Safety section at Novartis, Preclinical Safety (PCS) department. In this role you will collaborate with multi-disciplinary scientists to support the safety of LMW compounds and Cell & Gene Therapy products within the Novartis Research and Development portfolio.-
**Commitment to Diversity & Inclusion**:

- Novartis is committed to building an outstanding, inclusive work environment and diverse teams representative of the patients and communities we serve._

**Minimum requirements**
- Required skills: 
- Master’s degree or equivalent with work experience in molecular and computational biology as well as experience working in genome editing or viral research projects within academic and/or drug discovery settings.
-  Hands-on experience with molecular biology and biochemistry techniques (nucleic acid extraction, PCR, ddPCR / qPCR, western blot, cloning, cell culture). Prior experience in cytogenetics, viral integration site analysis, CRISPR off-target, library prep for NGS, chromosome conformation capture (3C, 4C, HiC) and/or rapid amplification of cDNA ends (RACE) is a plus.
-  Confidence working in a UNIX environment. Experienced with next generation sequencing data analysis and biostatistics. Solid programming skills in R or Python and/or previous experience in viral integration site analysis or CRISPR off-target is a plus.
-  Collaborative, flexible, critical thinking and strong team player.
-  Excellent organization and communication skills, independent, organized, and accurate working style, committed to high quality. 
- Fluent English (written and spoken)
- This role can be based in either Basel, Switzerland or Cambridge Mass. US.
- Why Novartis?
- 766 million lives were touched by Novartis medicines in 2021, and while we’re proud of this, we know there is so much more we could do to help improve and extend people’s lives.
- We believe new insights, perspectives and ground-breaking solutions can be found at the intersection of medical science and digital innovation. That a diverse, equitable and inclusive environment inspires new ways of working.
- We believe our potential can thrive and grow in an unbossed culture underpinned by integrity, curiosity and flexibility. And we can reinvent what's possible, when we collaborate with courage to aggressively and ambitiously tackle the world’s toughest medical challenges. Because the greatest risk in life, is the risk of never trying
- Imagine what you could do here at Novartis**Division**
- NIBR

**Business Unit**
- Translational Medicine

**Country**
- Switzerland

**Work Location**
- Basel

**Company/Legal Entity**
- Novartis Pharma AG

**Alternative Country 1**
- USA

**Functional Area**
- Research & Development

**Job Type**
- Full Time

**Employment Type**
- Regular

**Shift Work**
- No

**Early Talent**
- No



  • Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel Vollzeit

    The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated **Bioinformatician / Computational Biologist** to analyse single cell genomics data in support of IOB’s therapy development efforts. IOB is a research institute associated with the University of Basel which combines basic and clinical research. Its mission is...

  • Computational Biologist

    vor 7 Monaten


    Basel, Schweiz Novartis Vollzeit

    390850BR **Computational Biologist / Associate Data Scientist**: Switzerland **About the role** 250! The number of genomics research projects that are waiting for your data analysis expertise every year. Your work will be important towards faster discovery and development of next generation breakthrough therapies for unmet medical need. The Immunology...

  • Data Scientist

    Vor 2 Tagen


    Basel, Schweiz CSEM SA Vollzeit

    **Your mission** As a **Data Scientist / Computational Biologist**, you contribute to research and development projects by developing innovative algorithms and frameworks to solve our customers’ challenges. Through your creative ideas, you further support the definition of the technology roadmap. **Your responsibilities** - Application of...


  • Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel Vollzeit

    The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated **Postdoc **to join our multi-disciplinary team of scientists in the field of Molecular Biology and Molecular Genetics led by Professor Carlo Rivolta. IOB is a research institute associated with the University of Basel which combines basic and clinical research....


  • Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel Vollzeit

    IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for vision loss. It is a place where your expertise will be valued, your abilities challenged, and your knowledge expanded. We are seeking a dynamic and driven individual to join our team as...


  • Basel, Schweiz Friedrich Miescher Institute Vollzeit

    The Friedrich Miescher Institute for Biomedical Research (FMI) in Basel, Switzerland is a world-class research institute dedicated to investigating the molecular mechanisms of health and disease in the fields of neurobiology, genome regulation and multicellular systems. FMI research is supported by state-of-the-art core facilities, employing various...


  • Basel, Schweiz Friedrich Miescher Institute Vollzeit

    The Friedrich Miescher Institute for Biomedical Research (FMI) is a world-class research institute that investigates the molecular mechanisms of health and disease in the fields of neurobiology, genome regulation and multicellular systems. FMI research is supported by state-of-the-art core facilities, employing various cutting-edge technologies for imaging,...

  • Ai Research Scientist

    vor 7 Monaten


    Basel, Schweiz Panda International Vollzeit

    **AI Research Scientist**: **Location** - Basel, Switzerland **Business Sector** - AI **Job ref** - 22573 **Published** - about 14 hours ago **Key Responsibilities**: - Develop cutting-edge AI algorithms to analyze biological datasets and predict drug efficacy, safety, and pharmacokinetics. - Collaborate with a multidisciplinary team of scientists to...


  • Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel Vollzeit

    The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated **Research Assistant** to join the Human Retinal Circuits Group at IOB, led by Botond Roska. The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is a research institute combining basic and clinical research. Its mission is to drive innovations in...

  • Research Scientist

    vor 1 Woche


    Basel, Schweiz Novartis Vollzeit

    6500! That’s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential unveil therapeutic breakthroughs for patients. - Are you a curious, independent scientist eager to work on the development of the next generation...

  • Research Scientist

    vor 1 Woche


    Basel, Schweiz Novartis Vollzeit

    6500! That’s the number of associates in the Novartis Institutes for BioMedical Research (NIBR). This division is the innovation engine of Novartis, focusing on powerful new technologies that have the potential to unveil therapeutic breakthroughs for patients. - Are you a curious, independent scientist eager to work on the development of the next...

  • Research Assistant

    Vor 5 Tagen


    Basel, Schweiz Institute of Molecular and Clinical Ophthalmology Basel Vollzeit

    The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a motivated and skilled **Research Assistant / Lab Technician** to join the Ophthalmic Genetics Group. IOB is a research institute combining basic and clinical research. Its mission is to drive innovations in understanding vision and its diseases and develop new therapies for...


  • Basel, Schweiz Sobi Vollzeit

    **Company Description**: - Sobi offers the opportunity to work at an international pharmaceutical company focused on specialty pharmaceuticals meeting the high medical needs of rare disease patients and providing treatment and services to them. Our employees come from a variety of backgrounds within research, healthcare, industry and the academic...

  • Scientist, Molecular

    vor 2 Wochen


    Basel, Schweiz Ridgeline Discovery GmbH Vollzeit

    **Matterhorn Bioscience**s is looking for **a **Scientist, Molecular / Cellular Biology or Immunology**.** Matterhorn Biosciences is a preclinical stage biotechnology company pioneering the discovery and development of novel T cell therapy for cancer treatment. We are an exciting motivated group of scientists who are determined to make a difference for...


  • Basel, Schweiz Universität Basel Vollzeit

    The Institute of Molecular and Clinical Ophthalmology Basel (IOB) is seeking a highly motivated **Bioinformatician / Computational Biologist** to analyse single cell genomics data in support of IOB's therapy development efforts. IOB is a research institute associated with the University of Basel which combines basic and clinical research. Its mission is to...


  • Basel, Schweiz Proclinical Vollzeit

    Proclinical are recruiting Portfolio Safety Scientist for a global business. This is a contract role and is located in Basel, with the availability to work remotely from home. Our client is focused on detecting innovative remedies. **Responsibilities**: - Offer expert involvement to the development of the product safety method. - Expand and uphold a...

  • Safety Scientist

    vor 11 Stunden


    Basel, Schweiz SimplyVision GmbH Vollzeit

    For our customer located in Basel/Switzerland we are currently looking for a**:Safety Scientist **(M/F/d)** * To support internal team movements, we are looking for 3 Clinical Safety Scientist to join the group and hit the ground running. We need senior profile able to be independent, without extensive training. This is why we are looking for someone with a...


  • Basel, Schweiz Universität Basel Vollzeit

    The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need. With more than 70 research groups and 900 employees, the...


  • Basel, Schweiz Universität Basel Vollzeit

    The Department of Biomedicine is a joint effort between the University of Basel and the University Hospitals Basel. It unites basic and clinical scientists to advance our understanding of health and disease and to develop pioneering therapies benefiting the lives of patients in areas of unmet need. With more than 70 research groups and 900 employees, the...

  • Computational Biologist

    vor 7 Monaten


    Basel, Schweiz Bayer Vollzeit

    **At Bayer we’re visionaries, driven to solve the world’s toughest challenges and striving for a world where ,Health for all, Hunger for none’ is no longer a dream, but a real possibility. We’re doing it with energy, curiosity and sheer dedication, always learning from unique perspectives of those around us, expanding our thinking, growing our...